Aplyronine A, a potent antitumor macrolide of marine origin, and the congeners aplyronines B and C: isolation, structures, and bioactivities

Tetrahedron

Volumn 63, Issue 15, 2007, Pages 3138-3167

  Ojika, Makoto ^a   Kigoshi, Hideo ^b   Yoshida, Yoshifumi ^a   Ishigaki, Takeshi ^a   Nisiwaki, Masanori ^a   Tsukada, Itaru ^a   Arakawa, Masayuki ^c   Ekimoto, Hisao ^c   Yamada, Kiyoyuki ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

^c NIPPON KAYAKU CO LTD   (Japan)

Author keywords

Absolute stereostructure; Antitumor activity; Aplyronines; Cytotoxicity; Isolation; Marine natural products; Sea hare

Indexed keywords

ANTINEOPLASTIC AGENT; APLYRONINE A; APLYRONINE B; APLYRONINE C; APLYRONINE DERIVATIVE; MACROLIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; COLON CARCINOMA; CONTROLLED STUDY; CYTOTOXICITY; DEGRADATION; DRUG ACTIVITY; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; EHRLICH ASCITES TUMOR; ENANTIOSELECTIVITY; FEMALE; LEUKEMIA P 388; LEWIS CARCINOMA; MALE; MARINE SPECIES; MELANOMA B16; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL;

ANASPIDEA; APLYSIA KURODAI;

EID: 33847681881     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2007.02.011     Document Type: Article

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