NMR and cDNA array analysis prior to heart failure reveals an increase of unsaturated lipids, a glutamine/glutamate ratio decrease and a specific transcriptome adaptation in obese rat heart

Journal of Molecular and Cellular Cardiology

Volumn 42, Issue 3, 2007, Pages 526-539

  Roncalli, J ^a   Smih, F ^a   Desmoulin, F ^b   Dumonteil, N ^a   Harmancey, R ^a   Hennig, S ^c   Perez, L ^a   Pathak, A ^a   Galinier, M ^a   Massabuau, P ^a   Malet Martino, M ^b   Senard, J M ^a   Rouet, P ^a  

^a INSERM   (France)

^b UPS)   (France)

^c German Genome Resource Center RZPD   (Germany)

Author keywords

Arrays; Heart failure; Metabolome; NMR; Obesity; Transcriptome

Indexed keywords

GLUTAMIC ACID; GLUTAMINE; OMEGA 3 FATTY ACID; TAURINE; TRANSCRIPTOME; UNSATURATED FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA MICROARRAY; GENE EXPRESSION; GENE MUTATION; HEART FAILURE; HEART LEFT VENTRICLE; HOMOZYGOSITY; MALE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SPONTANEOUSLY HYPERTENSIVE HEART FAILURE RAT;

ADAPTATION, BIOLOGICAL; AGING; ANIMALS; GENE EXPRESSION PROFILING; GLUTAMATES; GLUTAMINE; HEART FAILURE, CONGESTIVE; INTRACELLULAR MEMBRANES; LIPID METABOLISM; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MULTIGENE FAMILY; OBESITY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; RATS; TRANSCRIPTION, GENETIC;

ANIMALIA; RATTUS;

EID: 33847672377     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2006.11.007     Document Type: Article

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