Pharmacokinetics of a novel amoxicillin paste formulation in cats

Journal of Veterinary Pharmacology and Therapeutics

Volumn 30, Issue 2, 2007, Pages 172-174

  Chicoine, A L ^a   Cox, W R ^b   Weich, E I ^c   Huang, L ^d   Wong, J ^d   Dowling, P M ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b Canadian Animal Health Management Services   (Canada)

^c Southwest Bio Labs   (United States)

^d JR Laboratories Inc   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; UNCLASSIFIED DRUG; VETOMOXIN;

ANIMAL EXPERIMENT; ARTICLE; CAT; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DETERMINATION; DRUG ELIMINATION; DRUG FORMULATION; DRUG HALF LIFE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PASTE; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

ADMINISTRATION, ORAL; AMOXICILLIN; ANIMALS; ANTI-BACTERIAL AGENTS; AREA UNDER CURVE; CATS; CHEMISTRY, PHARMACEUTICAL; MALE;

EID: 33847661881     PISSN: 01407783     EISSN: 13652885     Source Type: Journal    
DOI: 10.1111/j.1365-2885.2007.00829.x     Document Type: Article

References (14)

1. Aucoin, D. (2000) Wounds/abscess infection. In The Antimicrobial Reference Guide to Effective Treatment, 2nd edn. Ed. Aucoin, D., p. 35. North American Compendiums Inc., Port Huron, MI.
2. Boothe, D.M. (2001) Drug dosage tables. In Small Animal Clinical Pharmacology and Therapeutics. Ed. Boothe, D.M., p. 734. W.B. Saunders Company, Philadelphia, PA.
3. Gunderson, B.W., Ross, G.H., Ibrahim, K.H. & Rotschafer, J.C. (2001) What do we really know about antibiotic pharmacodynamics? Pharmacotherapy, 21, 302S-318S.
4. Hoshuyama, S., Kanoe, M. & Amimoto, A. (1996) Isolation of obligate and facultative anaerobic bacteria for feline subcutaneous abscesses. Journal of Veterinary Medical Science, 58, 273-274.
5. Jang, S.S., Breher, J.E., Dabaco, L.A. & Hirsh, D.C. (1997) Organisms isolated from dogs and cats with anaerobic infections and susceptibility to selected antimicrobial agents. Journal of the American Veterinary Medical Association, 210, 1610-1614.
6. Keefe, T.J. (1978) Results of a clinical study to determine frequency of dosage for amoxicillin trihydrate in cats. Veterinary Medicine Small Animal Clinician, 73, 447-450.
7. McKellar, Q.A., Sanchez Bruni, S.F. & Jones, D.G. (2004) Pharmacokinetic/ pharmacodynamic relationships of antimicrobial drugs used in veterinary medicine. Journal of Veterinary Pharmacology and Therapeutics, 27, 503-514.
8. Pires de Abreu, L.R., Ortiz, R.M., de Castro, S.C. & Pedrazzoli, J.J. (2003) HPLC determination of amoxicillin comparative bioavailability of healthy volunteers after a single dose administration. Journal of Pharmacy and Pharmaceutical Sciences, 6, 223-230.
9. Plumb, D.C. (2002) Amoxicillin. In Veterinary Drug Handbook, 4th edn, pp. 42-45. Iowa State Press, Ames, IA.
10. Roy, J., Messier, S., Labrecque, O. & Cox, W.R. (in press) Clinical and in vitro efficacy of amoxicillin against bacteria associated with feline skin wounds and abscesses. Canadian Veterinary Journal.
11. Senior, D.F., Gaskin, J.M., Buergelt, C.D., Franks, P.P. & Keefe, T.J. (1985) Amoxycillin and clavulanic acid combination in the treatment of experimentally induced bacterial cystitis in cats. Research in Veternary Science, 39, 42-46.
12. Toutain, P.L. & Lees, P. (2004) Integration and modelling of pharmacokinetic and pharmacodynamic data to optimize dosage regimens in veterinary medicine. Journal of Veterinary Pharmacology and Therapeutics, 27, 467-477.
13. Vree, T.B., Dammers, E. & van Duuren, E. (2002) Variable absorption of clavulanic acid after an oral dose of 25 mg/kg of clavubactin and synulox in healthy cats. Scientific World Journal, 2, 1369-1378.
14. Watson, A.D.J. & Rosin, E. (2000) Antimicrobial drug use in dogs and cats. In Antimicrobial Therapy in Veterinary Medicine, 3rd edn. Eds Prescott, J.F., Baggot, J.D. & Walker, R.D., pp. 537-575. Ames, IA.