Intra-Articular Morphine in Acute Pain Trials

Regional Anesthesia and Pain Medicine

Volumn 32, Issue 2, 2007, Pages 176-177

  Rosseland, Leiv Arne ^a   Solheim, Nina ^a   Stubhaug, Audun ^a,b  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

MORPHINE; PLACEBO; PROSTAGLANDIN E2;

ACUTE DISEASE; ANALGESIA; ANALGESIC ACTIVITY; CLINICAL TRIAL; DRUG EFFECT; DRUG USE; HUMAN; KNEE ARTHROSCOPY; LETTER; NOCICEPTION; OUTCOME ASSESSMENT; PAIN ASSESSMENT; POSTOPERATIVE PAIN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; SEX DIFFERENCE; STATISTICAL SIGNIFICANCE;

ANALGESICS, OPIOID; HUMANS; INJECTIONS, INTRA-ARTICULAR; MORPHINE; PAIN; PAIN MEASUREMENT; PATIENT SELECTION;

EID: 33847654697     PISSN: 10987339     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rapm.2006.12.004     Document Type: Letter

References (11)

1. Solheim N., Rosseland L.A., and Stubhaug A. Intraarticular morphine 5 mg after knee arthroscopy does not produce significant pain relief when administered to patients with moderate to severe pain via intraarticular catheter. Reg Anesth Pain Med 31 (2006) 506-513
2. Stein C. Intra-articular morphine for inflammatory pain. Reg Anesth Pain Med 31 (2006) 496-497
3. Lasagna L. The psychophysics of clinical pain. 22. Lancet 280 (1962) 572-575
4. Max M.B., and Laska E.M. Single-dose analgesic comparison. In: Max M.B., Portenoy R., and Laska E.M. (Eds). Advances in Pain Research and Therapy. (1991), Raven, New York, NY 281-304
5. Rosseland L.A., and Stubhaug A. Gender is a confounding factor in pain trials: Women report more pain than men after arthroscopic surgery. Pain 112 (2004) 248-253
6. Rosseland L.A. No evidence for analgesic effect of intra-articular morphine after knee arthroscopy: A qualitative systematic review. Reg Anesth Pain Med 30 (2005) 83-98
7. Breivik E.K., and Bjornsson G.A. Variation in surgical trauma and baseline pain intensity: Effects on assay sensitivity of an analgesic trial. Eur J Oral Sci 106 (1998) 844-852
8. Rosseland L.A., Stubhaug A., Sandberg L., and Breivik H. Intra-articular (IA) catheter administration of postoperative analgesics: A new trial design allows evaluation of baseline pain, demonstrates large variation in need of analgesics, and finds no analgesic effect of IA ketamine compared with IA saline. Pain 104 (2003) 25-34
9. Rosseland L.A., Stubhaug A., Grevbo F., Reikeras O., and Breivik H. Effective pain relief from IA saline with or without morphine 2 mg in patients with moderate-to-severe pain after knee arthroscopy: A randomized, double-blind controlled clinical study. Acta Anaesthesiol Scand 47 (2003) 732-738
10. 2 correlates with pain intensity after knee arthroscopic procedures. Anesth Analg 2007 (in press).
11. Rosseland LA. Pain after knee arthroscopy: Study methodology of intra-articular analgesic trials and clinical effects of intra-articular morphine, ketamine and saline. University of Oslo, Faculty of Medicine; 2005.