Intra-Articular Morphine 5 mg After Knee Arthroscopy Does Not Produce Significant Pain Relief When Administered to Patients With Moderate to Severe Pain via an Intra-Articular Catheter

Regional Anesthesia and Pain Medicine

Volumn 31, Issue 6, 2006, Pages 506-513

  Solheim, Nina ^a   Rosseland, Leiv Arne ^b   Stubhaug, Audun ^b,c  

^a LOVISENBERG DIAKONALE HOSPITAL   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c UNIVERSITY OF OSLO   (Norway)

Author keywords

Catheter; Intra Articular; Knee joint; Morphine; Pain; Randomized clinical trial

Indexed keywords

IBUPROFEN; IBUX; MORPHINE; NONSTEROID ANTIINFLAMMATORY AGENT; PARACET; PARACETAMOL; SODIUM CHLORIDE;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; FATIGUE; FEMALE; GENERAL ANESTHESIA; HUMAN; KNEE ARTHROSCOPY; MALE; NAUSEA; PAIN ASSESSMENT; PAIN THRESHOLD; PATIENT SELECTION; POSTOPERATIVE ANALGESIA; POSTOPERATIVE PAIN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE; SURGICAL PATIENT;

ADULT; ANALGESICS, OPIOID; ARTHROSCOPY; CATHETERS, INDWELLING; DEVICE REMOVAL; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; HUMANS; INJECTIONS, INTRA-ARTICULAR; KNEE JOINT; MALE; MIDDLE AGED; MORPHINE; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TREATMENT OUTCOME;

EID: 33751319698     PISSN: 10987339     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rapm.2006.06.206     Document Type: Article

References (35)

1. Stein C., Comisel K., Haimerl E., Yassouridis A., Lehrberger K., Herz A., and Peter K. Analgesic effect of intraarticular morphine after arthroscopic knee surgery. N Engl J Med 325 (1991) 1123-1126
2. Joshi G.P., McCarroll S.M., O'Brien T.M., and Lenane P. Intraarticular analgesia following knee arthroscopy. Anesth Analg 76 (1993) 333-336
3. Dalsgaard J., Felsby S., Juelsgaard P., and Froekjaer J. Low-dose intra-articular morphine analgesia in day case knee arthroscopy: A randomized double-blinded prospective study. Pain 56 (1994) 151-154
4. Ruwe P.A., Klein I., and Shields C.L. The effect of intraarticular injection of morphine and bupivacaine on postarthroscopic pain control. Am J Sports Med 23 (1995) 59-64
5. Aasbo V., Raeder J.C., Grogaard B., and Roise O. No additional analgesic effect of intra-articular morphine or bupivacaine compared with placebo after elective knee arthroscopy. Acta Anaesthesiol Scand 40 (1996) 585-588
6. Soderlund A., Westman L., Ersmark H., Eriksson E., Valentin A., and Ekblom A. Analgesia following arthroscopy-A comparison of intra-articular morphine, pethidine and fentanyl. Acta Anaesthesiol Scand 41 (1997) 6-11
7. Gupta A, Axelsson K, Allvin R, Liszka-Hackzell J, Rawal N, Althoff B, Augustini BG. Postoperative pain following knee arthroscopy: The effects of intra-articular ketorolac and/or morphine. Reg Anesth Pain Med 1999;24:225-230.
8. Stubhaug A, Breivik H. Postoperative analgesic trials: Some important issues. In: Breivik H, ed. Clinical Anaesthesiology. London: Baillière Tindall; 1995:555-584.
9. Rosseland L.A., Stubhaug A., Sandberg L., and Breivik H. Intra-articular (IA) catheter administration of postoperative analgesics. A new trial design allows evaluation of baseline pain, demonstrates large variation in need of analgesics, and finds no analgesic effect of IA ketamine compared with IA saline. Pain 104 (2003) 25-34
10. Rosseland L.A., Stubhaug A., Grevbo F., Reikeras O., and Breivik H. Effective pain relief from IA saline with or without morphine 2 mg in patients with moderate-to-severe pain after knee arthroscopy. A randomized, double-blind controlled clinical study. Acta Anaesthesiol Scand 47 (2003) 732-738
11. Rosseland L.A., Helgesen K.G., Breivik H., and Stubhaug A. Moderate-to-severe pain after knee arthroscopy is relieved by intraarticular saline: A randomized controlled trial. Anesth Analg 98 (2004) 1546-1551
12. Kalso E., Smith L., McQuay H., and Moore A. No pain, no gain: Clinical excellence and scientific rigour-Lessons learned from IA morphine. Pain 98 (2002) 269-275
13. Heard S.O., Edwards W.T., Ferrari D., Hanna D., Wong P.D., Liland A., and Willock M.M. Analgesic effect of intraarticular bupivacaine or morphine after arthroscopic knee surgery: A randomized, prospective, double-blind study. Anesth Analg 74 (1992) 822-826
14. McSwiney M.M., Joshi G.P., Kenny P., and McCarroll S.M. Analgesia following arthroscopic knee surgery. A controlled study of intra-articular morphine, bupivacaine or both combined. Anaesth Intensive Care 21 (1993) 201-203
15. Joshi G.P., McCarroll S.M., Cooney C.M., Blunnie W.P., O'Brien T.M., and Lawrence A.J. Intra-articular morphine for pain relief after knee arthroscopy. J Bone Joint Surg Br 74 (1992) 749-751
16. Bjornsson A., Gupta A., Vegfors M., Lennmarken C., and Sjoberg F. Intraarticular morphine for postoperative analgesia following knee arthroscopy. Reg Anesth 19 (1994) 104-108
17. Lyons B., Lohan D., Flynn C.G., Joshi G.P., O'Brien T.M., and McCarroll M. Intra-articular analgesia for arthroscopic meniscectomy. Br J Anaesth 75 (1995) 552-555
18. Cepeda M.S., Uribe C., Betancourt J., Rugeles J., and Carr D.B. Pain relief after knee arthroscopy: Intra-articular morphine, intra-articular bupivacaine, or subcutaneous morphine?. Reg Anesth 22 (1997) 233-238
19. Kanbak M., Akpolat N., Ocal T., Doral M.N., Ercan M., and Erdem K. Intraarticular morphine administration provides pain relief after knee arthroscopy. Eur J Anaesthesiol 14 (1997) 153-156
20. Denti M., Randelli P., Bigoni M., Vitale G., Marino M.R., and Fraschini N. Pre- and postoperative intra-articular analgesia for arthroscopic surgery of the knee and arthroscopy-assisted anterior cruciate ligament reconstruction. A double-blind randomized, prospective study. Knee Surg Sports Traumatol Arthrosc 5 (1997) 206-212
21. Alvarez-Cabo J.M., Lopez-Rouco M., and Gonzalez-Paleo J.R. Analgesic effect of intra-articular morphine after arthroscopic knee surgery. Ambul Surg 6 (1998) 179-182
22. Brandsson S., Karlson J., Morberg P., Rydgren B., Eriksson B.I., and Hedner T. Intraarticular morphine after arthroscopic ACL reconstruction: A double-blind placebo-controlled study of 40 patients. Acta Orthop Scand 71 (2000) 280-285
23. Follak N., and Ganzer D. Postoperative analgesic value of the intra-articular instillation of bupivacaine and morphine after arthroscopic knee surgery. Arch Orthop Trauma Surg 121 (2001) 278-281
24. Moher D., Schulz K.F., and Altman D.G. The CONSORT statement: Revised recommendations for improving the quality of reports of parallel group randomized trials. BMC Med Res Methodol 1 (2001) 2
25. Rosseland L.A., and Stubhaug A. Gender is a confounding factor in pain trials: Women report more pain than men after arthroscopic surgery. Pain 112 (2004) 248-253
26. Hoenig J.M., and Heisey D.M. The abuse of power: The pervasive fallacy of power calculations for data analysis. Am Stat 55 (2001) 19-24
27. Breivik E.K., Haanaes H.R., and Barkvoll P. Upside assay sensitivity in a dental pain model. Eur J Pain 2 (1998) 179-186
28. Richardson M.D., Bjorksten A.R., Hart J.A., and McCullough K. The efficacy of intra-articular morphine for postoperative knee arthroscopy analgesia. Arthroscopy 13 (1997) 584-589
29. Rosseland L.A. No evidence for analgesic effect of intra-articular morphine after knee arthroscopy: A qualitative systematic review. Reg Anesth Pain Med 30 (2005) 83-98
30. Highgenboten C.L., Jackson A.W., and Meske N.B. Arthroscopy of the knee. Ten-day pain profiles and corticosteroids. Am J Sports Med 21 (1993) 503-506
31. Rautoma P., Santanen U., Avela R., Luurila H., Perhoniemi V., and Erkola O. Diclofenac premedication but not intra-articular ropivacaine alleviates pain following day-case knee arthroscopy. Can J Anesth 47 (2000) 220-224
32. Ferreira S.H., and Nakamura M. II-Prostaglandin hyperalgesia: The peripheral analgesic activity of morphine, enkephalins and opioid antagonists. Prostaglandins 18 (1979) 191-200
33. Joris J.L., Dubner R., and Hargreaves K.M. Opioid analgesia at peripheral sites: A target for opioids released during stress and inflammation?. Anesth Analg 66 (1987) 1277-1281
34. Likar R., Sittl R., Gragger K., Pipam W., Blatnig H., Breschan C., Schalk H.V., Stein C., and Schafer M. Peripheral morphine analgesia in dental surgery. Pain 76 (1998) 145-150
35. Stein A., Yassouridis A., Szopko C., Helmke K., and Stein C. Intraarticular morphine versus dexamethasone in chronic arthritis. Pain 83 (1999) 525-532