Safety of rapid intravenous loading of valproate

Epilepsia

Volumn 48, Issue 3, 2007, Pages 478-483

  Limdi, Nita A ^a,c   Knowlton, Robert K ^a   Cofield, Stacey S ^b   Ver Hoef, Lawrence W ^a   Paige, Alfred L ^a   Dutta, Sandeep ^b   Faught, Edward ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c The University of Alabama at Birmingham   (United States)

Author keywords

Intravenous; Loading doses; Pharmacokinetics; Safety; Valproate

Indexed keywords

VALPROIC ACID;

ADULT; AGED; ANALYSIS OF VARIANCE; ARTICLE; BREATHING RATE; BURNING SENSATION; CARDIOVASCULAR DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; CONSCIOUSNESS LEVEL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG SAFETY; DRUG TOLERABILITY; DRUG TOLERANCE; ELECTROCARDIOGRAM; EPILEPSY; FEMALE; HEART ARRHYTHMIA; HEART MUSCLE CONDUCTION DISTURBANCE; HEART RATE; HUMAN; INFUSION RATE; INJECTION SITE IRRITATION; INJECTION SITE PHLEBITIS; INJECTION SITE REACTION; LIVER DISEASE; LOADING DRUG DOSE; MALE; MEAN ARTERIAL PRESSURE; NAUSEA; NEUROLOGIC DISEASE; OXYGEN SATURATION; PAIN; PARESTHESIA; PRIORITY JOURNAL; SEDATION; SIDE EFFECT; SKIN REDNESS; VITAL SIGN;

ADULT; AGED; ANALYSIS OF VARIANCE; ANTICONVULSANTS; BLOOD PRESSURE; CONSCIOUSNESS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; ELECTROCARDIOGRAPHY; EPILEPSY; FEMALE; HEART RATE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; TIME FACTORS; VALPROIC ACID;

EID: 33847647654     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2007.00989.x     Document Type: Article

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