Detection of HBsAg mutants in a population with a low prevalence of hepatitis B virus infection

Journal of Medical Virology

Volumn 79, Issue 4, 2007, Pages 351-355

  Gibb, Robert ^a   Nimmo, Graeme R ^a   O'Loughlin, Peter ^b   Lowe, Peter ^b   Drummond, David ^b  

^a ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^b QML Pathology   (Australia)

Author keywords

Abbott ARCHITECT; Bayer centaur assays; Escape mutation; HBV variants; Hepatitis B virus; Immunoassay

Indexed keywords

BIOLOGICAL MARKER; HEPATITIS B SURFACE ANTIGEN; VIRUS DNA;

ARTICLE; AUSTRALIA; CONTROLLED STUDY; DIAGNOSTIC PROCEDURE; DIAGNOSTIC VALUE; DNA SEQUENCE; EVALUATION; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; IMMUNOASSAY; MAJOR CLINICAL STUDY; NONHUMAN; PREVALENCE; SENSITIVITY AND SPECIFICITY; VIRAL GENETICS; VIRUS DETECTION; VIRUS MUTANT;

AUSTRALIA; HEPATITIS B; HEPATITIS B SURFACE ANTIGENS; HUMANS; IMMUNOASSAY; MUTATION; PREVALENCE; PROSPECTIVE STUDIES; RANDOM ALLOCATION; REAGENT KITS, DIAGNOSTIC; RETROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY;

HEPATITIS B VIRUS;

EID: 33847608754     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.20823     Document Type: Article

References (31)

1. Avellon A, Echevarria JM. 2006. Frequency of hepatitis B virus 'a' determinant variants in unselected Spanish chronic carriers. J Med Virol 78:24-36.
2. Ayers A, Locarnini S, Bartholomeusz A. 2004. HBV genotyping and analysis for unique mutations. Methods Mol Med 95:125-149.
3. Bartholomeusz A, Locarnini S, Ayres A, Thompson G, Sozzi V, Angus P, Sievert W, Sasadeusz J, Chalmers D, Cooper M. 2004. Molecular modeling of hepatitis B virus polymerase and adefovir resistance identifies three clusters of mutations. Hepatology 40:246A.
4. Basuni AA, Carman WF. 2004. HBV vaccine-escape variants. Methods Mol Med 95:115-124.
5. Basuni AA, Butterworth L, Cooksley G, Locarnini S, Carman WF. 2004. Prevalence of HBsAg mutants and impact of hepatitis B infant immunisation in four Pacific Island countries. Vaccine 22:2791-2799.
6. Blum HE. 1995. Variants of hepatitis B, C and D viruses: Molecular biology and clinical significance. Digestion 56:85-95.
7. Carman WF, Zanetti AR, Karayiannis P, Waters J, Manzillo G, Tanzi E, Zuckerman AJ, Thomas HC. 1990. Vaccine-induced escape mutant of hepatitis B virus. Lancet 336:325-329.
8. Cooreman MP, van Roosmalen MH, te Morsche R, Sunnen CM, de Ven EM, Jansen JB, Tytgat GN, de Wit PL, Paulij WP. 1999. Characterization of the reactivity pattern of murine monoclonal antibodies against wild-type hepatitis B surface antigen to G145R and other naturally occurring "a" loop escape mutations. Hepatology 30:1287-1292.
9. Cooreman MP, Leroux-Roels G, Paulij WP. 2001. Vaccine- and hepatitis B immune globulin-induced escape mutations of hepatitis B virus surface antigen. J Biomed Sci 8:237-247.
10. Fattovich G. 2003. Natural history and prognosis of hepatitis B. Semin Liver Dis 23:47-58.
11. Fischer L, Sterneck M, Muller-Ruchholtz C, Gish R, Will H. 1999. Hepatitis B virus variants associated with clinically severe recurrence after liver transplantation. Transplant Proc 31:492-493.
12. Fujii H, Moriyama K, Sakamoto N, Kondo T, Yasuda K, Hiraizumi Y, Yamazaki YM, Sakaki Y, Okochi K, Nakajima E. 1992. Gly145 to Arg substitution in HBs antigen of immune escape mutant of hepatitis B virus. Biochem Biophys Res Commun 184:1152-1157.
13. Gan RB, Chu MJ, Shen LP, Qian SW, Li ZP. 1987. The complete nucleotide sequence of the cloned DNA of hepatitis B virus subtype adr in pADR-1. Sci. Sin B 1987 30:507-521.
14. Harrison TJ, Hopes EA, Oon CJ, Zanetti AR, Zuckerman AJ. 1991. Independent emergence of a vaccine-induced escape mutant of hepatitis B virus. J Hepatol 13:8105-107.
15. Hou J, Karayiannis P, Waters J, Luo K, Liang C, Thomas HC. 1995. A unique insertion in the S gene of surface antigen-negative hepatitis B virus Chinese carriers. Hepatology 21:273-278.
16. Howard CR, Brown SE, Hogben DN, Zuckerman AJ, Murray-Lyon IN, Steward MW. 1984. Analysis of antibody responses to hepatitis B surface antigen. In: Vyas GN, Dienstag JL, Hoofnagle JH, editors. Viral Hepatitis and Liver Disease. Florida: Grune & Stratton. p 571-572.
17. Huang X, Lu D, Ji G, Sun Y, Ma L, Chen Z, Zhang L, Huang J, Yu L. 2004. Hepatitis B virus (HBV) vaccine-induced escape mutants of HBV S gene among children from Qidong area, China. Virus Res 99:63-68.
18. Ijaz S, Ferns RB, Tedder RS. 2003. A 'first loop' linear epitope accessible on native hepatitis B surface antigen that persists in the face of 'second loop' immune escape. J Gen Virol 84:269-275.
19. Jilg W. 1998. Novel hepatitis B vaccines. Vaccine 16:865-8.
20. Karthigesu VD, Allison LM, Fortuin M, Mendy M, Whittle HC, Howard CR. 1994. A novel hepatitis B virus variant in the sera of immunized children. J Gen Virol 75:443-448.
21. Lee WM. 1997. Hepatitis B virus infection. N Engl J Med 337:1733-1745.
22. Liu Z, Luo K, He H, Hou J. 2005. Hot-spot mutations in hepatitis B virus core gene: Eliciting or evading immune clearance? J Viral Hepat 12:146-153.
23. Locarnini S, McMillan J, Bartholomeusz A. 2003. The hepatitis B virus and common mutants. Semin Liver Dis 23:5-20.
24. Okamoto H, Imai M, Kametani M, Nakamura T, Mayumi M. 1987. Genomic heterogeneity of hepatitis B virus in a 54-year-old woman who contracted the infection through materno-fetal transmission. Jpn J Exp Med 57:231-236.
25. Pramoolsinsup C. 2002. Management of viral hepatitis B. J Gastroenterol Hepatol 17:8125-145.
26. Protzer-Knolle U, Naumann U, Bartenschlager R, Berg T, Hopf U, Meyer zum Buschenfelde KH, Neuhaus P, Gerken G. 1998. Hepatitis B virus with antigenically altered hepatitis B surface antigen is selected by high-dose hepatitis B immune globulin after liver transplantation. Hepatology 27:254-263.
27. Rehermann B, Nascimbeni M. 2005. Immunology of hepatitis B virus and hepatitis C virus infection. Nat Rev Immunol 5:215-229.
28. Scheiblauer H, Soboll H, Nick S. 2006. Evaluation of 17 CE-marked HbsAg assays with respect to clinical sensitivity, analytical sensitivity, and hepatitis B virus mutant detection. J Med Virol 78:S66-S70.
29. Tillmann HL, Trautwein C, Bock T, Boker KH, Jackel E, Glowienka MK, Oldhafer MK, Bruns I, Gauthier J, Condreay LD, Raab HR, Manns MP. 1999. Mutational pattern of hepatitis B virus on sequential therapy with famciclovir and lamivudine in patients with hepatitis B virus reinfection occurring under HBIg immunoglobulin after liver transplantation. Hepatology 30:244-256.
30. Torresi J. 2002. The virological and clinical significance of mutations in the overlapping envelope and polymerase genes of hepatitis B virus. J Clin Virol 25:97-106.
31. Yamamoto K, Horikita M, Tsuda F, Itoh K, Akahane Y, Yotsumoto S, Okamoto H, Miyakawa Y, Mayumi M. 1994. Naturally occurring escape mutants of hepatitis B virus with various mutations in the S gene in carriers seropositive for antibody to hepatitis B surface antigen. J Virol 68:2671-2676.