Recruitment pharmacophore for interleukin 5 receptor α antagonism

Biopolymers - Peptide Science Section

Volumn 88, Issue 1, 2007, Pages 83-93

  Bhattacharya, Madhushree ^a   Pillalamari, Udaya ^a   Sarkhel, Sanjay ^a   Ishino, Tetsuya ^a   Urbina, Cecilia ^a   Jameson, Bradford ^a   Chaiken, Irwin ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Cyclic peptide inhibitor; Interleukin 5; Pharmacophore; Receptor antagonism

Indexed keywords

CYCLIC PEPTIDE INHIBITORS; HYPEREOSINOPHILIC DISEASES; INTERLEUKIN 5; RECEPTOR ANTAGONISM;

AMINO ACIDS; CELLS; DISEASES; ENZYME INHIBITION; HYDROGEN BONDS; HYDROPHOBICITY;

POLYPEPTIDES;

AF 17121; ARGININE; ARGININE 6; CYCLOPEPTIDE; CYCLOPEPTIDE INHIBITOR; INTERLEUKIN 5; INTERLEUKIN 5 RECEPTOR ALPHA; PEPTIDE LIBRARY; UNCLASSIFIED DRUG;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IC 50; MUTAGENESIS; PHARMACOPHORE; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; SPECTROSCOPY;

AMINO ACID SEQUENCE; ARGININE; BINDING SITES; BINDING, COMPETITIVE; CELL LINE; HUMANS; HYDROPHOBICITY; INTERLEUKIN-5 RECEPTOR ALPHA SUBUNIT; MODELS, MOLECULAR; PEPTIDES, CYCLIC; STRUCTURE-ACTIVITY RELATIONSHIP; SURFACE PLASMON RESONANCE; THERMODYNAMICS;

EID: 33847416579     PISSN: 00063525     EISSN: 10970282     Source Type: Journal    
DOI: 10.1002/bip.20612     Document Type: Article

References (38)

1. Barnes, P. J. Annu Rev Pharmacol Toxicol 2002, 42, 81-98.
2. Nicola, N. Guidebook to Cytokines and Their Receptors; Oxford University Press: New York, 1994; pp 171-177.
3. Katz, B. A. Annu Rev Biophys Biomol Struct 1997, 26, 27-45.
4. Sidhu, S. S.; Fairbrother, W. J.; Deshayes, K. Chembiochem 2003, 4, 14-25.
5. Uchiyama, F.; Tanaka, Y.; Minari, Y.; Tokui, N. J Biosci Bioeng 2005, 99, 448-456.
6. Hruby, V. J. Nat Rev Drug Discov 2002, 1, 847-858.
7. Sidhu, S. S. Drug Discov Today 2001, 6, 936.
8. Plaetinck, G.; Van der Heyden, J.; Tavernier, J.; Fache, I.; Tuypens, T.; Fischkoff, S.; Fiers, W.; Devos, R. J Exp Med 1990, 172, 683-691.
9. Tavernier, J.; Devos, R.; Cornelis, S.; Tuypens, T.; Van der Heyden, J.; Fiers, W.; Plaetinck, G. Cell 1991, 66, 1175-1184.
10. Lopez, A. F.; Vadas, M. A.; Woodcock, J. M.; Milton, S. E.; Lewis, A.; Elliott, M. J.; Gillis, D.; Ireland, R.; Olwell, E.; Park, L. S. J Biol Chem 1991, 266, 24741-24747.
11. Kitamura, T.; Sato, N.; Arai, K.; Miyajima, A. Cell 1991, 66, 1165-1174.
12. Foster, P. S.; Hogan, S. P.; Yang, M.; Mattes, J.; Young, I. G.; Matthaei, K. I.; Kumar, R. K.; Mahalingam, S.; Webb, D. C. Trends Mol Med 2002, 8, 162-167.
13. Ishino, T.; Robertson, N.; Chaiken, I. Vitam Horm 2005, 71, 321-344.
14. McKinnon, M.; Banks, M.; Solari, R.; Robertson, G. Marcel Dekker: New York, 1999.
15. England, B. P.; Balasubramanian, P.; Uings, I.; Bethell, S.; Chen, M. J.; Schatz, P. J.; Yin, Q.; Chen, Y. F.; Whitehorn, E. A.; Tsavaler, A.; Martens, C. L.; Barrett, R. W.; McKinnon, M. Proc Natl Acad Sci USA 2000, 97, 6862-6867.
16. Ruchala, P.; Varadi, G.; Ishino, T.; Scibek, J.; Bhattacharya, M.; Urbina, C.; Ryk, D. V.; Uings, I.; Chaiken, I. Biopolymers 2004, 73, 556-568.
17. Graber, P.; Proudfoot, A. E.; Talabot, F.; Bernard, A.; McKinnon, M.; Banks, M.; Fattah, D.; Solari, R.; Peitsch, M. C.; Wells, T. N. J Biol Chem 1995, 270, 15762-15769.
18. Wu, S. J.; Li, J.; Tsui, P.; Cook, R.; Zhang, W.; Hu, Y.; Canziani, G.; Chaiken, I. J Biol Chem 1999, 274, 20479-20488.
19. Tavernier, J.; Tuypens, T.; Plaetinck, G.; Verhee, A.; Fiers, W.; Devos, R. Proc Natl Acad Sci USA 1992, 89, 7041-7045.
20. Anthony, A.; Nangia, A.; Desiraju, G. R.; Jaskolski, M. Chem Commun 1998, 22, 2537-2538.
21. Sarkhel, S.; Desiraju, G. R. Proteins 2004, 54, 247-259.
22. Desiraju, G. R. The Weak Hydrogen Bond in Structural Chemistry and Biology; Oxford University Press: New York, 1999.
23. Sidhu, S. S. Curr Opin Biotechnol 2000, 11, 610-616.
24. Gibbs, A. C.; Bjorndahl, T. C.; Hodges, R. S.; Wishart, D. S. J Am Chem Soc 2002, 124, 1203-1213.
25. Athanassiou, Z.; Dias, R. L.; Moehle, K.; Dobson, N.; Varani, G.; Robinson, J. A. J Am Chem Soc 2004, 126, 6906-6913.
26. Burley, S. K.; Petsko, G. A. FEBS Lett 1986, 203, 139-143.
27. Gallivan, J. P.; Dougherty, D. A. Proc Natl Acad Sci USA 1999, 96, 9459-9464.
28. Meyer, E. A.; Castellano, R. K.; Diederich, F. Angew Chem Int Ed Engl 2003, 42, 1210-1250.
29. Crowley, P. B.; Golovin, A. Proteins 2005, 59, 231-239.
30. Ishino, T.; Urbina, C.; Bhattacharya, M.; Panarello, D.; Chaiken, I. J Biol Chem 2005, 280, 22951-22961.
31. Ishino, T.; Pasut, G.; Scibek, J.; Chaiken, I. J Biol Chem 2004, 279, 9547-9556.
32. Scibek, J. J.; Evergren, E.; Zahn, S.; Canziani, G. A.; Van Ryk, D.; Chaiken, I. M. Anal Biochem 2002, 307, 258-265.
33. Pace, C. N.; Vajdos, F.; Fee, L.; Grimsley, G.; Gray, T. Protein Sci 1995, 4, 2411-2423.
34. Li, J.; Cook, R.; Dede, K.; Chaiken, I. J Biol Chem 1996, 271, 1817-1820.
35. van Gunsteren, W.; Billster, S.; Eising, A.; Hunenberger, P.; Kruger, P.; Mark, A.; Scott, W.; Tironi, I. Biomolecular Simulation: The GROMOS96 Manual and User Guide; Hochschulverlag AG an der ETH: Zurich, Switzerland, 1996.
36. Berendsen, H.; Postma, J.; van Gunsteren, W.; Hermans, J. Reidel: Dordrecht, Netherlands, 1981.
37. Ryckaert, J.; Ciocitti, G.; Berendsen, H. J Comput Phys 1977, 23.
38. Laskowski, R.; MacArthur, M.; Moss, D.; Thorton, J. J Appl Crystallogr 1993, 26, 283-291.