Randomization of the receptor α chain recruitment epitope reveals a functional interleukin-5 with charge depletion in the CD loop

Journal of Biological Chemistry

Volumn 274, Issue 29, 1999, Pages 20479-20488

  Wu, Sheng Jiun ^a   Li, Jun ^b,c   Tsui, Ping ^b   Cook, Richard ^b   Zhang, Wentao ^a   Hu, Yin ^a   Canziani, Gabriela ^a   Chaiken, Irwin ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b GLAXOSMITHKLINE   (United Kingdom)

^c BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 5; INTERLEUKIN 5 RECEPTOR;

ALPHA CHAIN; ARTICLE; HUMAN; HUMAN CELL; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING;

EID: 0033575276     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.29.20479     Document Type: Article

References (35)

1. Sanderson, C. J. (1992) Adv. Pharmacol. 23, 163-177
2. Milburn, M. V., Hassell, A. M., Lambert, M. H., Jordan, S. R., Proudfoot, A. E. I., Graber, P., and Wells, T. N. C. (1993) Nature 363, 172-176
3. Murata, Y., Takaki, S., Migita, M., Kikuchi, Y., Tominaga, A., and Takatsu, K. (1992) J. Exp. Med. 175, 341-351
4. Tavernier, J., Tuypens, A. V., Plaetinck, R. D., Heyden, J. V., Cuisez, Y., and Oefner, C. (1995) Proc . Natl. Acad. Sci. U. S. A. 92, 5194-5198
5. Graber, P., Proudfoot, A. E., Talabot, F., Bernard, A., McKinnon, M., Banks, M., Fattah, D., Solari, R., Peitsch, M. C., and Wells, T. N. (1995) J . Biol. Chem. 270, 15762-15769
6. Morton, T., Li, J., Cook, R., and Chaiken, I. (1995) Proc . Natl. Acad. Sci. U. S. A. 92, 10879-10883
7. Clackson, T., and Wells, J. A. (1994) Trends Biotechnol. 12, 173-184
8. Lowman, H. B., Cunningham, B. C., and Wells, J. A. (1991) J. Biol. Chem. 266, 10982-10988
9. Baca, M., Presta, L. G., O'Connor, S. J., and Wells, J. A. (1997) J. Biol. Chem. 272, 10678-10684
10. Muller, Y. A., Li, B., Christinger, H. W., Wells, J. A., Cunningham, B. C., and de Vos, A. M. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 7192-7197
11. Proudfoot, A. E. I., Fattah, D., Kawashima, E. H., Bernard, A., and Wingfield, P. T. (1990) Biochem. J. 270, 357-361
12. Li, J., Cook, R., Dede, K., and Chaiken, I. (1996) J. Biol. Chem. 271, 1817-1820
13. Tsui, P., Tornetta, M. A., Ames, R. S., Bankosky, B. C., Greigo, S., Silverman, C., Porter, T., Moore, G., and Sweet, R. W. (1996) J. Immunol. 157, 772-780
14. Zhong, G., and Smith, G. P. (1994) BioTechnigues 16, 838-839
15. Li, J., Cook, R., Hensley, P., Doyle, M., McNulty, D., and Chaiken, I. (1997) Proc . Natl. Acad. Sci. U. S. A. 94, 6694-6699
16. Jones, J. T., Ballinger, M. D., Pisacane, P. I., Lofgren, J. A., Fitzpatrick, V. D., Fairbrother, W. J., Wells, J. A., and Sliwkowski, M. X. (1998) J. Biol. Chem. 273, 11667-11674
17. Kay, B. K., Adey, N. B., He, Y.-S., Manfredi, J. P., Mataragnon, A. H., and Fowlkes, D. M. (1993) Gene (Amst.) 128, 59-65
18. Lowman, H. B., and Wells, J. A. (1993) J. Mol . Biol. 234, 564-578
19. Toniatti, C., Cabibbo, A., Sporeno, E., Salvati, A. L. Cerretani, M., Serafini, S., Lahm, A., Cortese, R., and Ciliberto, G. (1996) EMBO J. 15, 2726-2737
20. Ames, R. S., Tornetta, M. A., McMillan, L. J., Kaiser, K. F., Holmes, S. D., Appelbaum, E., Cusimano, D. M., Theisen, T. W., Gross, M. S., Jones, C. S., Silverman, C., Porter, T. G., Cook, R. M., Bennet, D. and Chaiken, I. M. (1995) J. Immunol. 154, 6355-6364
21. Laemmli, U. K. (1970) Nature 227, 680-685
22. Monfardini, C., Ramamoorthy, M., Rosenbaum, H., Fang, Q., Godillot, P. A., Canziani, G., Chaiken, I. M., and Williams, W. V. (1998) J. Biol. Chem. 273, 7657-7667
23. Morton, T., Bennett, D. B., Appelbaum, E. R., Cusimano, D. M., Johanson, K. O., Matico, R. E., Young, P. R., Doyle, M., and Chaiken, I. M. (1994) J. Mol. Recognit. 7, 47-55
24. Li, J., Cook, R., and Chaiken, I. (1996) J. Biol. Chem. 271, 31729-31734
25. Burton, D. R., and Barbas, C. F., III (1993) Immunomethods 3, 155-163
26. Bass, S., Greene, R., and Wells, J. A. (1990) Proteins 8, 309-314
27. Reidhaar-olson, J. F., and Sauer, R. T. (1988) Science 241, 53-57
28. Cabibbo, A., Sporeno, E., Toniatti, C., Altamura, S., Savino, R., Paonessa, G. and Ciliberto, G. (1995) Gene (Amst.) 167, 41-47
29. Saggio, I., Gloaguen, I., Poiana, G., and Laufer, R. (1995) EMBO J. 14, 3045-3054
30. Buckli, P. J., Wu, Z., and Ciardelli, T. L. (1997) Arch. Biochem. Biophys. 339, 79-84
31. Dickason, R. R., and Huston, D. P. (1996) Nature 379, 652-655
32. Edgerton, M. D., Graber, P., Willard, D., Consler, T., McKinnon, M., Uings, I., Arod, C. Y., Borlat, F., Fish, R., Peitsch, M., Wells, T. N. C., and Proudfoot, A. E. I. (1997) J. Biol. Chem. 272, 20611-20618
33. Chaiken, I. M., and Proudfoot, A. (1999) in IL 5: From Molecule to Drug Target for Asthma (Sanderson, C. J., ed) Marcel Dekker Inc., New York, pp. 167-188
34. Bagley, C. J., Woodcock, J. M., Stomski, F. C., and Lopes, A. F. (1999) in IL 5: From Molecule to Drug Target for Asthma (Sanderson, C. J., ed) Marcel Dekker Inc., New York, pp. 189-203
35. Chong, L. T., Dempster, S. E., Hendsch, Z. S., Lee, L.-P., and Tidor, B. (1998) Protein Sci. 7, 206-210