Co-administration of ketoconazole and tacrolimus therapy: A transplanted rat model

International Urology and Nephrology

Volumn 38, Issue 3-4, 2006, Pages 713-718

  Sabry, Alaa ^a   El Agroudy, Amgad ^a   Sheashaa, Hussein ^a   Hawas, Samia ^b   El Shahat, Fagr B ^b   Barakat, Nashwa ^a  

^a MANSOURA UNIVERSITY   (Egypt)

^b MANSOURA UNIVERSITY   (Egypt)

Author keywords

Experimental; FK506; Ketoconazole

Indexed keywords

CREATININE; KETOCONAZOLE; TACROLIMUS;

ADD ON THERAPY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG BLOOD LEVEL; DRUG DOSE REDUCTION; DRUG SAFETY; EXPERIMENTAL MODEL; KIDNEY TRANSPLANTATION; MALE; NONHUMAN; RAT; RAT STRAIN; WEIGHT REDUCTION;

ANIMALS; IMMUNOSUPPRESSIVE AGENTS; KETOCONAZOLE; MALE; RATS; RATS, SPRAGUE-DAWLEY; TACROLIMUS;

EID: 33847386694     PISSN: 03011623     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11255-006-0062-x     Document Type: Article

References (19)

1. Dubernared JM (1985) Transplantation of kidney in rats. In: Wagenkncht LV (ed) Microsurgery in urology. Thieme Inc., New York, pp 56-60
2. Tanaka H, Kuroda A, Marusawa H, Hashimoto M, Hatanaka H, Kino T, Goto T, Okuhara M (1987) Physicochemical properties of FK-506, a novel immunosuppressant isolated from Streptomyces tsukubaensis. Transplant Proc 19(5 Suppl 6):11-16
3. Yoshimura N, Oka T (1990) FK506, a new immunosuppressive agent. A Review J Immunol Immunopharmacol 10:32-36
4. Todo S, Murase N, Ueda Y, Podesta L, ChapChap P, Kahn D, Okuda K, Imventarza O, Casavilla A, Demetris J, et al (1988) Effect of FK506 in experimental organ transplantation. Transplant Proc 20(1 Suppl 1):215-219
5. Christians U, Braun F, Kosan N, et al (1991) High performance liquid chromatography/mass spectrometry of FK506 and its metabolites in blood, bile and urine of liver grafted patients. Transplantation Proc 23(6):2741-2744
6. Volker K, Reinhard B (1998) Tacrolimus in Kidney transplantation. a clinical review. Nephron 79:8-20
7. White DJG, Blatchford NR, Gauwenbergh G (1984) Cyclosporine and ketoconazole. Transplantation 37:214-215
8. Sobh M, Hamdy A, El-Agroudy A, El-Sayed K, El-Diasty T, Bakr A, Ghoniem M (2001) Co-administration of ketoconazole and cyclosporine for kidney transplantation: Long-term follow-up and study of metabolic consequences. Am J Kidney Disk 37(3):510-517
9. Zheng Z, Christopher S, John D, Calvin S, David G, Robert Z (1995) Improved techniques for kidney transplantation in mice. Microsurgery 16:103-109
10. Jakabowski HD (1985) Renal transplantation in the rat. In: Tiede A, Deltz E, Engemann R, Hamelmann H (eds) Microsurgical models in rats for Transplantation Research. Springer-Verlag, New York Heidelberg Berlin Tkyo, pp 47-50
11. Isai H, Painter DM, Sheil AG (1990): FK 506 and orthotopic liver transplantation in the rat. Transplant Proc 22(5):2125-2126
12. Yokoyama I, Uchida K, Fukao K, Ochiai T, Takahashi K, Endo T, Oshima S, Ishibashi M, Takahara S, Iwasaki Y, et al (1995) FK 506: Long-term study in kidney transplantation. Japanese FK 506 Study Group. Transplant Proc 27(1):818-821
13. Jiang H, Fujitsu T, Sakuma S, Ogawa T, Tamura K, Fujii Y, Akiyama Y, Izumi S, Takahara S, Ishibashi M, et al (1995) Immunosuppressive effects of FK 506 on rat renal allograft survival, in comparison with cyclosporine. Transplant Proc 27(1):367-369
14. Kino T, Hatanaka H, Miyata S, Inamura N, Nishiyama M, Yajima T, Goto T, Okuhara M, Kohsaka M, Aoki H, et al (1987) FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro. J Antibiot 40(9):1256-1265
15. Hayakawa K, Hata M, Nishiyama T, Ohashi M, Ishikawa M (1996) Maintenance of unresponsiveness by short-term pulse therapy with FK 506 in rat transplantation. Transplant Proc 28(3):1830-1831
16. Iwasaki K, Matsuda H, Nagase K, Shiraga T, Tokuma Y, Uchida K (1993) Effects of twenty-three drugs on the metabolism of FK506 by human liver microsomes. Res Commun Chem Pathol Pharmacol 82(2):209-216
17. Manez R, Martin M, Raman D, Silverman D, Jain A, Warty V, Gonzalez-Pinto I, Kusne S, Starzl TE (1994) Fluconazole therapy in transplant recipients receiving FK506. Transplantation 57(10):1521-1523
18. Newton DJ, Wang RW, Lu AY (1995) Cytochrome P450 inhibitors. Evaluation of specificities in the in vitro metabolism of therapeutic agents by human liver microsomes. Drug Metab Dispos 23(1):154-158
19. Mayer AD, Dmitrewski J, Squifflet JP, et al (1997) Multicenter randomized trial comparing tacrolimus (FK506) and cyclosporine in the prevention of renal allograft rejection: A report of the European Tacrolimus Multicenter Renal Study Group. Transplantation 64(3):436-443