Tacrolimus in kidney transplantation. A clinical review

Nephron

Volumn 79, Issue 1, 1998, Pages 8-20

  Klient, Volker ^a   Brunkhorst, Reinhard ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; AZATHIOPRINE; CARBAMAZEPINE; CLARITHROMYCIN; CLOTRIMAZOLE; CORTICOSTEROID; CYCLOSPORIN A; DANAZOL; DILTIAZEM; ERYTHROMYCIN; FLUCONAZOLE; IMIPRAMINE; ISONIAZID; KETOCONAZOLE; LYMPHOCYTE ANTIBODY; METHYLPREDNISOLONE; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; OKT 3; OMEPRAZOLE; PREDNISOLONE; PREDNISONE; RIFAMPICIN; TACROLIMUS; THYMOCYTE ANTIBODY; VERAPAMIL;

ACNE; ADULT; ADVERSE DRUG REACTION; ARTICLE; CARDIOVASCULAR DISEASE; CASE REPORT; CLINICAL RESEARCH; DIABETES MELLITUS; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG MECHANISM; DRUG METABOLISM; DRUG MONITORING; DRUG STRUCTURE; DRUG TISSUE LEVEL; GASTROINTESTINAL DISEASE; GINGIVA HYPERPLASIA; GRAFT REJECTION; HIRSUTISM; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; IMMUNOSUPPRESSIVE TREATMENT; INFECTION; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY DISEASE; KIDNEY TRANSPLANTATION; LIVER DISEASE; LYMPHOPROLIFERATIVE DISEASE; MALE; NEUROLOGIC DISEASE; ORAL DRUG ADMINISTRATION; PANCREAS TRANSPLANTATION; PRIORITY JOURNAL;

CREATININE; CYCLOSPORINE; DIURESIS; GRAFT REJECTION; GRAFT SURVIVAL; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; MULTICENTER STUDIES; MUROMONAB-CD3; TACROLIMUS;

EID: 0031954013     PISSN: 00282766     EISSN: None     Source Type: Journal    
DOI: 10.1159/000044985     Document Type: Article

References (6)

1. Kino T, Hatanaka H, Hashimoto M, Nishiyama M, Goto T, Okuhara M, Kohsaka M, Aoki H, Imanaka H: FK-506, a novel immunosuppressant isolated from a Streptomyces. Antibiotics 1987;40:1249-1255.
2. Peters DH, Fitton A, Plosker GL, Faulds D: Tacrolimus. A review of its pharmacology, and therapeutic potential in hepatic and renal transplantation. Drugs 1993;46:746-794.
3. Mayer AD, Dmitrewski J, Squifflet J-P, Besse T, Grabensee B, Klein B, Eigler F, Heemann U, Pichlmayr R, Behrend M, Vanrenterghem Y, Donck J, van Hooff J, Christiaans M, Morales JM, Andres A, Johnson RWG, Short C, Buchholz B, Rehmert N, Land W, Schleibner S, Forsythe JLR, Talbot D, Neumayer H-H, Hauser I, Ericzon B-G, Brattström C, Claesson K, Mühlbacher F, Pohanka E: Multicenter randomized trial comparing tacrolimus (FK-506) and cyclosporine in the prevention of renal allograft rejection. Transplantation 1997;64: 436-443.
4. Schreiber SL: Chemistry and biology of the immunophilins and their immunosuppressive ligands. Science 1991;251:283-287.
5. Schreiber SL, Crabtree GR: The mechanism of action of cyclosporin A and FK-506. Immunol Today 1992;13:136-142.
6. Bierer BE, Somers PK, Wandless TJ, Burakoff SJ, Schreiber SL: Probing immunosuppressant action with a nonnatural immunophilin ligand. Science 1990;250:556-559.