Neuroprotective peptides prevent some alcohol-induced alteration in γ-aminobutyric acid A-β3, which plays a role in cleft lip and palate and learning in fetal alcohol syndrome

American Journal of Obstetrics and Gynecology

Volumn 196, Issue 3, 2007, Pages 259.e1-259.e5

  Toso, Laura ^a   Roberson, Robin ^a   Abebe, Daniel ^a   Spong, Catherine Y ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

fetal alcohol syndrome; learning; mouse; N methyl D aspartate (NMDA); aminobutyric acid A (GABA)

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ALCOHOL; NEUROPEPTIDE; RECEPTOR SUBUNIT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CLEFT LIP; CLEFT LIP PALATE; CLEFT PALATE; CONTROLLED STUDY; CRANIOFACIAL MALFORMATION; EMBRYO; EMBRYO DEVELOPMENT; FETAL ALCOHOL SYNDROME; FETUS; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRENATAL EXPOSURE; PRIORITY JOURNAL;

EID: 33847379713     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2007.01.015     Document Type: Article

References (24)

1. Centers for Disease Control and Prevention (CDC). Behavioral risk factor surveillance system. Atlanta, GA: US Department of Health and Human Services, CDC. Last accessed: Dec 5, 2006. Available at: http://www.cdc.gov/brfss.
2. Sokol R.J., Delaney-Black V., and Nordstrom B. Fetal alcohol spectrum disorder. JAMA 290 (2003) 2996-2999
3. Sulik K. Genesis of alcohol-induced craniofacial dysmorphism: genesis of alcohol-induced craniofacial dysmorphism. Exp Biol Med (Maywood) 230 (2005) 366-375
4. Webster W.S., Walsh D.A., Lipson A.H., and McEwen S.E. Teratogenesis after acute alcohol exposure in inbred and outbred mice. Neurobehav Teratol 2 (1980) 227-234
5. Endres M., Toso L., Roberson R., et al. Prevention of alcohol-induced developmental delays and learning abnormalities in a model of fetal alcohol syndrome. Am J Obstet Gynecol 193 (2005) 1028-1034
6. Vink J., Auth J., Abebe D.T., Brenneman D.E., and Spong C.Y. Novel peptides prevent alcohol-induced spatial learning deficits and proinflammatory cytokine release in a mouse model of fetal alcohol syndrome. Am J Obstet Gynecol 193 (2005) 825-829
7. Spong C.Y., Abebe D.T., Gozes I., Brenneman D.E., and Hill J.M. Prevention of fetal demise and growth restriction in a mouse model of fetal alcohol syndrome. J Pharmacol Exp Ther 297 (2001) 774-779
8. Homanics G.E., DeLorey T.M., Firestone L.L., et al. Mice devoid of γ-aminobutyrate type A receptor β3 subunit have epilepsy, cleft palate, and hypersensitive behavior. Proc Natl Acad Sci 94 (1997) 4143-4148
9. Murray J.C., and Schutte B.C. Cleft palate: players, pathways, and pursuits. J Clin Invest 113 (2004) 1676-1678
10. Culiat C.T., Stubbs L.J., Woychik R.P., Russell L.B., Johnson D.K., and Rinchik E.M. Deficiency of the β3 subunit of the type A γ-aminobutyric acid receptor causes cleft palate in mice. Nature 11 (1995) 344-346
11. A-receptor β3 subunit gene as the Angelman's syndrome gene. Lancet 341 (1993) 122-123
12. A receptors. Brain Res 29 (1999) 196-217
13. A receptors and impairs spatial learning in the guinea pig. Behav Brain Res 150 (2004) 117-125
14. Boehm SL I.I., Ponomarev I., Jennings A.W., et al. γ-Aminobutyric acid A receptor subunit mutant mice: new perspectives on alcohol actions. Biochem Pharm 68 (2004) 1581-1602
15. Mitsuyama H., Little K.Y., Sieghart W., Deavud L., and Morrow A.L. GABA A receptor alpha1, alpha4, and beta3 subunit mRNA and protein expression in the frontal cortex of human alcoholics. Alcohol Clin Exp Res 22 (1998) 815-822
16. Chen S.Y., Charness M.E., Wilkemeyer M.F., and Sulik K.K. Peptide-mediated protection from ethanol-induced neural tube defects. Dev Neurosci 27 (2005) 13-19
17. Webster W.S., Walsh D.A., Lipson A.H., and McEwen S.E. Teratogenesis after acute alcohol exposure in inbred and out bred mice. Neurobehav Toxicol 2 (1980) 227-234
18. Kerrigan J.J., Mansell J.P., Sengupta A., Brown N., and Sandy J.R. Palatogenesis and potential mechanisms for clefting. J R Coll Surg Edinb 45 (2000) 351-358
19. Lotosh E.A. Development of palate in normal murine embryo and influence of various agents on the conditions of palatine plates at different stages of embryonic development. Acta Chir Plast 10 (1968) 1-6
20. Wang K.-Y., and Diewert V.M. A morphometric analysis of craniofacial growth in cleft lip and noncleft mice. J Craniofac Genet Dev Biol 12 (1992) 141-154
21. Hagiwara N., Katarova Z., Siracusa L.D., and Brilliant M.H. Nonneuronal expression of the GABAβ3 subunit gene is required for normal palate development in mice. Dev Biol 254 (2003) 93-101
22. Toso L., Poggi S.H., Roberson R., et al. Prevention of alcohol-induced learning deficits in fetal alcohol syndrome mediated through NMDA and GABA receptors. Am J Obstet Gynecol 194 (2006) 681-686
23. Toso L., Endres M., Vink J., Abebe D.T., Brenneman D.E., and Spong C.Y. Learning enhancement with neuropeptides. Am J Obstet Gynecol 194 (2006) 1153-1159
24. Jovanovic J.N., Thomas P., Kittler J.T., Smart T., and Moss S.J. Brain-derived neurotrophic factor modulates fast synaptic inhibition by regulating GABAA receptor phosphorylation, activity, and cell-surface stability. J Neurosci 24 (2004) 522-530