메뉴 건너뛰기




Volumn 6, Issue 2, 2007, Pages 562-569

Target-specific cytotoxic activity of recombinant immunotoxin scFv(MUC1)-ETA on breast carcinoma cells and primary breast tumors

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; IMMUNOTOXIN; MUCIN 1; PSEUDOMONAS EXOTOXIN; PSEUDOMONAS EXOTOXIN A; RECOMBINANT ANTIBODY; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

EID: 33847372521     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-06-0604     Document Type: Article
Times cited : (33)

References (28)
  • 1
    • 0024353046 scopus 로고
    • A core protein epitope of the polymorphic epithelial mucin detected by the monoclonal antibody SM-3 is selectively exposed in a range of primary breast carcinoma
    • Girling A, Bartkova J, Burchell J, Gendler S, Gillett C, Taylor-Papadimitriou J. A core protein epitope of the polymorphic epithelial mucin detected by the monoclonal antibody SM-3 is selectively exposed in a range of primary breast carcinoma. Int J Cancer 1989;43:1072-6.
    • (1989) Int J Cancer , vol.43 , pp. 1072-1076
    • Girling, A.1    Bartkova, J.2    Burchell, J.3    Gendler, S.4    Gillett, C.5    Taylor-Papadimitriou, J.6
  • 2
    • 4143099166 scopus 로고    scopus 로고
    • MUC1 overexpression results in mammary gland tumorigenesis and prolonged alveolar differentiation
    • Schroeder JA, Masri AA, Adriance MC, et al. MUC1 overexpression results in mammary gland tumorigenesis and prolonged alveolar differentiation. Oncogene 2004;23:5739-47.
    • (2004) Oncogene , vol.23 , pp. 5739-5747
    • Schroeder, J.A.1    Masri, A.A.2    Adriance, M.C.3
  • 3
    • 10744220453 scopus 로고    scopus 로고
    • Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents
    • Ren J, Agata N, Chen D, et al. Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents. Cancer Cell 2004;5:163-75.
    • (2004) Cancer Cell , vol.5 , pp. 163-175
    • Ren, J.1    Agata, N.2    Chen, D.3
  • 4
    • 0023741252 scopus 로고
    • A highly immunogenic region of human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats
    • Gendler S, Taylor-Papadimitrou J, Duhig T, Rothbard J, Bruchell J. A highly immunogenic region of human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats. J Biol Chem 1988;263:12820-3.
    • (1988) J Biol Chem , vol.263 , pp. 12820-12823
    • Gendler, S.1    Taylor-Papadimitrou, J.2    Duhig, T.3    Rothbard, J.4    Bruchell, J.5
  • 5
    • 0035958851 scopus 로고    scopus 로고
    • Identification and topology of variant sequences within individual repeat domains of the human epithelial tumor mucin MUC1
    • Engelmann K, Baldus SE, Hanisch FG. Identification and topology of variant sequences within individual repeat domains of the human epithelial tumor mucin MUC1. J Biol Chem 2001;276:27764-9.
    • (2001) J Biol Chem , vol.276 , pp. 27764-27769
    • Engelmann, K.1    Baldus, S.E.2    Hanisch, F.G.3
  • 6
    • 0023617395 scopus 로고
    • Development and characterization of breast cancer reactive monoclonal antibodies directed to the core protein of the human milk mucin
    • Burchell J, Gendler S, Taylor-Papadimitrou J, et al. Development and characterization of breast cancer reactive monoclonal antibodies directed to the core protein of the human milk mucin. Cancer Res 1987;47:5476-82.
    • (1987) Cancer Res , vol.47 , pp. 5476-5482
    • Burchell, J.1    Gendler, S.2    Taylor-Papadimitrou, J.3
  • 8
    • 6844257550 scopus 로고    scopus 로고
    • Summary report on the ISOBM TD-4 Workshop: Analysis of 56 monoclonal antibodies against the MUC1 mucin
    • Price MR, Rye PD, Petrakou E, et al. Summary report on the ISOBM TD-4 Workshop: analysis of 56 monoclonal antibodies against the MUC1 mucin. Tumor Biol 1998;19:1-20.
    • (1998) Tumor Biol , vol.19 , pp. 1-20
    • Price, M.R.1    Rye, P.D.2    Petrakou, E.3
  • 9
    • 0032189703 scopus 로고    scopus 로고
    • Human single-chain Fv antibodies to MUC1 core peptide selected from phage display libraries recognize unique epitopes and predominantly bind adenocarcinoma
    • Henderikx P, Kandilogiannaki M, Petrarca C, et al. Human single-chain Fv antibodies to MUC1 core peptide selected from phage display libraries recognize unique epitopes and predominantly bind adenocarcinoma. Cancer Res 1998;58:4324-32.
    • (1998) Cancer Res , vol.58 , pp. 4324-4332
    • Henderikx, P.1    Kandilogiannaki, M.2    Petrarca, C.3
  • 10
    • 0036174958 scopus 로고    scopus 로고
    • A mutated superantigen SEA D227A fusion diabody specific to MUC1 and D3 in targeted cancer immunotherapy in bile duct carcinoma
    • Takemura S, Kudo T, Asano R, et al. A mutated superantigen SEA D227A fusion diabody specific to MUC1 and D3 in targeted cancer immunotherapy in bile duct carcinoma. Cancer Immunol Immunother 2002;51:33-44.
    • (2002) Cancer Immunol Immunother , vol.51 , pp. 33-44
    • Takemura, S.1    Kudo, T.2    Asano, R.3
  • 11
    • 19944393861 scopus 로고    scopus 로고
    • Phase I trial of a murine antibody to MUC1 in patients with metastatic cancer: Evidence for the activation of humoral and cellular antitumor immunity
    • de Bono JS, Rha SY, Stephenson J, et al. Phase I trial of a murine antibody to MUC1 in patients with metastatic cancer: evidence for the activation of humoral and cellular antitumor immunity. Ann Oncol 2004; 15:1825-33.
    • (2004) Ann Oncol , vol.15 , pp. 1825-1833
    • de Bono, J.S.1    Rha, S.Y.2    Stephenson, J.3
  • 12
    • 0034063270 scopus 로고    scopus 로고
    • Clathrin-mediated endocytosis of MUC1 is modulated by its glycosylation state
    • Altschuler Y, Kinlough CL, Poland PA, et al. Clathrin-mediated endocytosis of MUC1 is modulated by its glycosylation state. Mol Biol Cell 2000;11:819-31.
    • (2000) Mol Biol Cell , vol.11 , pp. 819-831
    • Altschuler, Y.1    Kinlough, C.L.2    Poland, P.A.3
  • 17
    • 1542297653 scopus 로고    scopus 로고
    • Recombinant immunotoxins and retargeted killer cells: Employing engineered antibody fragments for tumor-specific targeting of cytotoxin effectors
    • Weis W, Biburger M, Muller T, et al. Recombinant immunotoxins and retargeted killer cells: employing engineered antibody fragments for tumor-specific targeting of cytotoxin effectors. Cancer Immunol Immunother 2004;53:217-26.
    • (2004) Cancer Immunol Immunother , vol.53 , pp. 217-226
    • Weis, W.1    Biburger, M.2    Muller, T.3
  • 18
    • 0042674300 scopus 로고    scopus 로고
    • Design, expression, purification, and characterization, in vitro and in vivo, of an antimelanoma single-chain Fv antibody fused to the toxin gelonin
    • Rosenblum MG, Cheung LH, Liu Y, Marks JW III. Design, expression, purification, and characterization, in vitro and in vivo, of an antimelanoma single-chain Fv antibody fused to the toxin gelonin. Cancer Res 2003;63: 3995-4002.
    • (2003) Cancer Res , vol.63 , pp. 3995-4002
    • Rosenblum, M.G.1    Cheung, L.H.2    Liu, Y.3    Marks III, J.W.4
  • 19
    • 27144451436 scopus 로고    scopus 로고
    • Diphtheria toxin fused to variant human interleukin-3 induces cytotoxicity of blasts from patients with acute myeloid leukemia according to the level of interleukin-3 receptor expression
    • Testa U, Riccioni R, Biffoni M, et al. Diphtheria toxin fused to variant human interleukin-3 induces cytotoxicity of blasts from patients with acute myeloid leukemia according to the level of interleukin-3 receptor expression. Blood 2005;106:2527-9.
    • (2005) Blood , vol.106 , pp. 2527-2529
    • Testa, U.1    Riccioni, R.2    Biffoni, M.3
  • 20
    • 25844517682 scopus 로고    scopus 로고
    • Phase I clinical study of the recombinant antibody toxin scFv(FRP5)-ETA specific for the ErbB2/HER2 receptor in patients with advanced solid malignomas
    • von Minckwitz G, Harder S, Hovelmann S, et al. Phase I clinical study of the recombinant antibody toxin scFv(FRP5)-ETA specific for the ErbB2/ HER2 receptor in patients with advanced solid malignomas. Breast Cancer Res 2005;7:R617-26.
    • (2005) Breast Cancer Res , vol.7
    • von Minckwitz, G.1    Harder, S.2    Hovelmann, S.3
  • 22
    • 0028985881 scopus 로고
    • EGF receptor and p185erbB-2-specific single-chain antibody toxins differ in their cell-killing activity on tumour cells expressing both receptor proteins
    • Weis W, Beerli R, Hellmann P, et al. EGF receptor and p185erbB-2-specific single-chain antibody toxins differ in their cell-killing activity on tumour cells expressing both receptor proteins. Int J Cancer 1995;60: 137-44.
    • (1995) Int J Cancer , vol.60 , pp. 137-144
    • Weis, W.1    Beerli, R.2    Hellmann, P.3
  • 23
    • 0029737778 scopus 로고    scopus 로고
    • Targeted inhibition of tumour cell growth bispecific single-chain toxin containing an antibody domain and TGFα
    • Schmidt M, Weis W. Targeted inhibition of tumour cell growth bispecific single-chain toxin containing an antibody domain and TGFα. Br J Cancer 1996;74:853-62.
    • (1996) Br J Cancer , vol.74 , pp. 853-862
    • Schmidt, M.1    Weis, W.2
  • 24
    • 0026486446 scopus 로고
    • Selective inhibition of tumour cell growth by recombinant single chain antibody toxin specific for the erbB2 receptor
    • Weis W, Harwerth IM, Mueller M, Groner B, Hynes NE. Selective inhibition of tumour cell growth by recombinant single chain antibody toxin specific for the erbB2 receptor. Cancer Res 1992;52: 6310-7.
    • (1992) Cancer Res , vol.52 , pp. 6310-6317
    • Weis, W.1    Harwerth, I.M.2    Mueller, M.3    Groner, B.4    Hynes, N.E.5
  • 25
    • 0344305415 scopus 로고    scopus 로고
    • Premalignant lesions as targets for cancer vaccines
    • Finn OJ. Premalignant lesions as targets for cancer vaccines. J Exp Med 2003;198:1623-6.
    • (2003) J Exp Med , vol.198 , pp. 1623-1626
    • Finn, O.J.1
  • 26
    • 0028908860 scopus 로고
    • Cytotoxic activity of chimeric toxins containing the epidermal growth factor-like domain of heregulins fused to PE38KDEL, a truncated recombinant form of Pseudomonas exotoxin
    • Kihare A, Pastan I. Cytotoxic activity of chimeric toxins containing the epidermal growth factor-like domain of heregulins fused to PE38KDEL, a truncated recombinant form of Pseudomonas exotoxin. Cancer Res 1995;55:72-7.
    • (1995) Cancer Res , vol.55 , pp. 72-77
    • Kihare, A.1    Pastan, I.2
  • 27
    • 0034087465 scopus 로고    scopus 로고
    • Recombinant antibody toxins specific for erbB-2 and EGF receptor inhibit the in vitro growth of human head and neck cancer cells and cause rapid tumour regression in vivo
    • Azemar M, Schmidt M, Artl F, et al. Recombinant antibody toxins specific for erbB-2 and EGF receptor inhibit the in vitro growth of human head and neck cancer cells and cause rapid tumour regression in vivo. Int J Cancer 2000;86:269-75.
    • (2000) Int J Cancer , vol.86 , pp. 269-275
    • Azemar, M.1    Schmidt, M.2    Artl, F.3
  • 28
    • 0027369480 scopus 로고
    • Mechanism of action of Pseudomonas exotoxin. Identification of rate-limiting step
    • Zdanovsky AG, Chiron M, Pastan I, FitzGerald DJ. Mechanism of action of Pseudomonas exotoxin. Identification of rate-limiting step. J Biol Chem 1993;268:21791-9.
    • (1993) J Biol Chem , vol.268 , pp. 21791-21799
    • Zdanovsky, A.G.1    Chiron, M.2    Pastan, I.3    FitzGerald, D.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.