Deinococcus radiodurans RNA ligase exemplifies a novel ligase clade with a distinctive N-terminal module that is important for 5′-PO4 nick sealing and ligase adenylylation but dispensable for phosphodiester formation at an adenylylated nick

Nucleic Acids Research

Volumn 35, Issue 3, 2007, Pages 839-849

  Raymond, Amy ^a   Shuman, Stewart ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE PHOSPHATE; ADENYLYLTRANSFERASE; ALANINE; ARGININE; ESTER; GLUTAMINE; GLYCINE; HISTIDINE; LYSINE; NUCLEOTIDYLTRANSFERASE; PHENYLALANINE; PHOSPHODIESTER; RNA LIGASE; SERINE; THREONINE; TRANSFERASE; UNCLASSIFIED DRUG;

ADENYLATION; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DEINOCOCCUS RADIODURANS; ENZYME ACTIVITY; MUTANT; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ALANINE; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; DEINOCOCCUS; EUKARYOTIC CELLS; EVOLUTION, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; RNA; RNA LIGASE (ATP); SEQUENCE HOMOLOGY; STRUCTURE-ACTIVITY RELATIONSHIP;

DEINOCOCCUS RADIODURANS; EUKARYOTA;

EID: 33847348459     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkl1090     Document Type: Article

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