Synthesis and antimalarial activity of new isotebuquine analogues

Journal of Medicinal Chemistry

Volumn 50, Issue 4, 2007, Pages 889-896

  Miroshnikova, Olga V ^a   Hudson, Thomas H ^a   Gerena, Lucia ^a   Kyle, Dennis E ^a   Lin, Ai J ^a  

^a WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (TERT BUTYLAMINOMETHYL) 4' CHLORO 5 (7 CHLOROQUINOLIN 4 YLAMINO)BIPHENYL 3 OL; 4 AMINOPHENOL; 4 AMINOQUINOLINE DERIVATIVE; 6 (TERT BUTYLAMINOMETHYL) 4' CHLORO 5 (7 CHLOROQUINOLIN 4 YLAMINO)BIPHENYL 3 OL; 6 (TERT BUTYLAMINOMETHYL) 5 (7 CHLOROQUINOLIN 4 YLAMINO) 4' TRIFLUOROMETHYLBIPHENYL 3 OL; AMODIAQUINE; ANTIMALARIAL AGENT; MANNICH BASE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; QUINONE DERIVATIVE; TEBUQUINE; UNCLASSIFIED DRUG;

AGRANULOCYTOSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DRUG EFFECT; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; LIVER TOXICITY; MOUSE; NONHUMAN; PLASMODIUM FALCIPARUM;

ANIMALS; ANTIMALARIALS; BIPHENYL COMPOUNDS; DRUG RESISTANCE; MAGNETIC RESONANCE SPECTROSCOPY; MALARIA; MICE; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33847344577     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm061232x     Document Type: Article

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