Inhibition of chitin synthase by a series of 7-deoxycasuarine stereoisomers designed as constrained analogues of the potent inhibitor 6-deoxyhomoDMDP

Natural Product Research

Volumn 21, Issue 1, 2007, Pages 76-82

  Behr, J B ^a   Gainvors Claisse, A ^b   Belarbi, A ^b  

^a UNIVERSITÉ DE REIMS CHAMPAGNE ARDENNE   (France)

^b UNIVERSITÉ DE REIMS CHAMPAGNE ARDENNE   (France)

Author keywords

Chitin synthase; Iminosugars; Inhibition; Pyrrolizidines

Indexed keywords

6 DEOXYHOMOL 2,5 DIDEOXY2,5 IMINO DEXTRO MANNITOL DERIVATIVE; 7 DEOXYCASUARINE DERIVATIVE; CHITIN SYNTHASE; GLYCOSYLTRANSFERASE INHIBITOR; IMINOSUGAR; PYRROLIZIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENZYME INHIBITION; STEREOISOMERISM;

ALKALOIDS; CHITIN SYNTHASE; ENZYME INHIBITORS; GLYCOSIDE HYDROLASES; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; PYRROLES; PYRROLIZIDINE ALKALOIDS; SACCHAROMYCES CEREVISIAE; STEREOISOMERISM;

EID: 33847327320     PISSN: 14786419     EISSN: 14786427     Source Type: Journal    
DOI: 10.1080/14786410601035993     Document Type: Article

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