Total Mesorectal Excision and Pelvic Node Dissection for Rectal Cancer: An Appraisal

Surgical Oncology Clinics of North America

Volumn 16, Issue 1, 2007, Pages 177-197

  Mortenson, Melinda M ^a   Khatri, Vijay P ^a   Bennett, Joseph J ^b   Petrelli, Nicholas J ^b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HELEN F GRAHAM CANCER CENTER   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANASTOMOSIS LEAKAGE; BLADDER FUNCTION; CANCER ADJUVANT THERAPY; CANCER RECURRENCE; CANCER SURVIVAL; HUMAN; LAPAROSCOPIC SURGERY; LYMPH NODE DISSECTION; LYMPH NODE METASTASIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PELVIS LYMPH NODE; PREOPERATIVE EVALUATION; PREOPERATIVE RADIOTHERAPY; RECTUM CANCER; RECTUM RESECTION; REVIEW; SEXUAL FUNCTION; SURGICAL TECHNIQUE;

ANASTOMOSIS, SURGICAL; DIGESTIVE SYSTEM SURGICAL PROCEDURES; HUMANS; LAPAROSCOPY; LYMPH NODE EXCISION; LYMPHATIC METASTASIS; MAGNETIC RESONANCE IMAGING; NEOADJUVANT THERAPY; NEOPLASM RECURRENCE, LOCAL; PARASYMPATHETIC NERVOUS SYSTEM; PELVIS; RADIOTHERAPY, ADJUVANT; RECTAL NEOPLASMS; RECTUM; SURGICAL STAPLING; SURVIVAL ANALYSIS;

EID: 33847300150     PISSN: 10553207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.soc.2006.10.007     Document Type: Review

References (99)

1. Jemal A., Siegel R., Ward E., et al. Cancer statistics, 2006. CA Cancer J Clin 56 2 (2006) 106-130
2. Goldberg S., and Klas J.V. Total mesorectal excision in the treatment of rectal cancer: a view from the USA. Semin Surg Oncol 15 2 (1998) 87-90
3. Ridgway P.F., and Darzi A.W. The role of total mesorectal excision in the management of rectal cancer. Cancer Control 10 3 (2003) 205-211
4. Kapiteijn E., and van de Velde C.J. The role of total mesorectal excision in the management of rectal cancer. Surg Clin North Am 82 5 (2002) 995-1007
5. Heald R.J. A new approach to rectal cancer. Br J Hosp Med 22 3 (1979) 277-281
6. Enker W.E., Thaler H.T., Cranor M.L., et al. Total mesorectal excision in the operative treatment of carcinoma of the rectum. J Am Coll Surg 181 4 (1995) 335-346
7. Madoff R.D., and Dykes S.L. What's new in colon and rectal surgery. J Am Coll Surg 198 1 (2004) 91-104
8. Enker W.E. Total mesorectal excision-the new golden standard of surgery for rectal cancer. Ann Med 29 2 (1997) 127-133
9. Bruch H.P., Schwandner O., Schiedeck T.H., et al. Actual standards and controversies on operative technique and lymph-node dissection in colorectal cancer. Langenbecks Arch Surg 384 2 (1999) 167-175
10. Godlewski G., and Prudhomme M. Embryology and anatomy of the anorectum: basis of surgery. Surg Clin North Am 80 1 (2000) 319-343
11. Heald R.J., and Moran B.J. Embryology and anatomy of the rectum. Semin Surg Oncol 15 2 (1998) 66-71
12. Havenga K., Maas C.P., DeRuiter M.C., et al. Avoiding long-term disturbance to bladder and sexual function in pelvic surgery, particularly with rectal cancer. Semin Surg Oncol 18 3 (2000) 235-243
13. Townsend C.M. Sabiston textbook of surgery: the biological basis of modern surgical practice. 17th edition (2004), W B Saunders, St. Louis (MO)
14. Heald R.J. The 'Holy Plane' of rectal surgery. J R Soc Med 81 9 (1988) 503-508
15. Khatri V.P., and Asensio J.A. Operative surgery manual. 1st edition (2003), W.B. Saunders, St. Louis (MO)
16. Jones O.M., Smeulders N., Wiseman O., et al. Lateral ligaments of the rectum: an anatomical study. Br J Surg 86 4 (1999) 487-489
17. DiDio L.J., Diaz-Franco C., Schemainda R., et al. Morphology of the middle rectal arteries: a study of 30 cadaveric dissections. Surg Radiol Anat 8 4 (1986) 229-236
18. Nano M., Levi A.C., Borghi F., et al. Observations on surgical anatomy for rectal cancer surgery. Hepatogastroenterology 45 21 (1998) 717-726
19. Jeong S.Y., Chessin D.B., and Guillem J.G. Surgical treatment of rectal cancer: radical resection. Surg Oncol Clin N Am 15 1 (2006) 95-107
20. Maurer C.A. Urinary and sexual function after total mesorectal excision. Recent Results Cancer Res 165 (2005) 196-204
21. Curti G., Maurer C.A., and Buchler M.W. Colorectal carcinoma: is lymphadenectomy useful?. Dig Surg 15 3 (1998) 193-208
22. Nelson H., Petrelli N., Carlin A., et al. Guidelines 2000 for colon and rectal cancer surgery. J Natl Cancer Inst 93 8 (2001) 583-596
23. Wang C., Zhou Z., Wang Z., et al. Patterns of neoplastic foci and lymph node micrometastasis within the mesorectum. Langenbecks Arch Surg 390 4 (2005) 312-318
24. Galandiuk S., Chaturvedi K., and Topor B. Rectal cancer: a compartmental disease. The mesorectum and mesorectal lymph nodes. Recent Results Cancer Res 165 (2005) 21-29
25. Topor B., Acland R., Kolodko V., et al. Mesorectal lymph nodes: their location and distribution within the mesorectum. Dis Colon Rectum 46 6 (2003) 779-785
26. Heald R.J., and Ryall R.D. Recurrence and survival after total mesorectal excision for rectal cancer. Lancet 1 8496 (1986) 1479-1482
27. Birbeck K.F., Macklin C.P., Tiffin N.J., et al. Rates of circumferential resection margin involvement vary between surgeons and predict outcomes in rectal cancer surgery. Ann Surg 235 4 (2002) 449-457
28. Heald R.J., Moran B.J., Ryall R.D., et al. Rectal cancer: the Basingstoke experience of total mesorectal excision, 1978-1997. Arch Surg 133 8 (1998) 894-899
29. Havenga K., Enker W.E., Norstein J., et al. Improved survival and local control after total mesorectal excision or D3 lymphadenectomy in the treatment of primary rectal cancer: an international analysis of 1411 patients. Eur J Surg Oncol 25 4 (1999) 368-374
30. Marr R., Birbeck K., Garvican J., et al. The modern abdominoperineal excision: the next challenge after total mesorectal excision. Ann Surg 242 1 (2005) 74-82
31. Bolognese A., Cardi M., Muttillo I.A., et al. Total mesorectal excision for surgical treatment of rectal cancer. J Surg Oncol 74 1 (2000) 21-23
32. Chessin D.B., and Guillem J.G. Abdominoperineal resection for rectal cancer: historic perspective and current issues. Surg Oncol Clin N Am 14 3 (2005) 569-586
33. Daniels I.R., Moran B.J., and Heald R.J. Surgery alone: is total mesorectal excision sufficient for rectal cancer?. Front Radiat Ther Oncol 38 (2004) 28-36
34. Wibe A., Rendedal P.R., Svensson E., et al. Prognostic significance of the circumferential resection margin following total mesorectal excision for rectal cancer. Br J Surg 89 3 (2002) 327-334
35. Improved survival with preoperative radiotherapy in resectable rectal cancer. Swedish Rectal Cancer Trial. N Engl J Med 336 14 (1997) 980-987
36. Kapiteijn E., Marijnen C.A., Nagtegaal I.D., et al. Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. N Engl J Med 345 9 (2001) 638-646
37. Kapiteijn E., Kranenbarg E.K., Steup W.H., et al. Total mesorectal excision (TME) with or without preoperative radiotherapy in the treatment of primary rectal cancer: prospective randomised trial with standard operative and histopathological techniques. Dutch ColoRectal Cancer Group. Eur J Surg 165 5 (1999) 410-420
38. Quirke P., Durdey P., Dixon M.F., et al. Local recurrence of rectal adenocarcinoma due to inadequate surgical resection: histopathological study of lateral tumour spread and surgical excision. Lancet 2 8514 (1986) 996-999
39. Brown G., Davies S., Williams G.T., et al. Effectiveness of preoperative staging in rectal cancer: digital rectal examination, endoluminal ultrasound or magnetic resonance imaging?. Br J Cancer 91 1 (2004) 23-29
40. Solomon M.J., and McLeod R.S. Endoluminal transrectal ultrasonography: accuracy, reliability, and validity. Dis Colon Rectum 36 2 (1993) 200-205
41. Kwok H., Bissett I.P., and Hill G.L. Preoperative staging of rectal cancer. Int J Colorectal Dis 15 1 (2000) 9-20
42. Beets-Tan R.G., and Beets G.L. Rectal cancer: review with emphasis on MR imaging. Radiology 232 2 (2004) 335-346
43. Garcia-Aguilar J., Pollack J., Lee S.H., et al. Accuracy of endorectal ultrasonography in preoperative staging of rectal tumors. Dis Colon Rectum 45 1 (2002) 10-15
44. Beets-Tan R.G., Beets G.L., Vliegen R.F., et al. Accuracy of magnetic resonance imaging in prediction of tumour-free resection margin in rectal cancer surgery. Lancet 357 9255 (2001) 497-504
45. Burton S., Brown G., Daniels I.R., et al. MRI directed multidisciplinary team preoperative treatment strategy: the way to eliminate positive circumferential margins?. Br J Cancer 94 3 (2006) 351-357
46. Janjan N.A., Khoo V.S., Abbruzzese J., et al. Tumor downstaging and sphincter preservation with preoperative chemoradiation in locally advanced rectal cancer: the M.D. Anderson Cancer Center experience. Int J Radiat Oncol Biol Phys 44 5 (1999) 1027-1038
47. Chen C.C., Lee R.C., Lin J.K., et al. How accurate is magnetic resonance imaging in restaging rectal cancer in patients receiving preoperative combined chemoradiotherapy?. Dis Colon Rectum 48 4 (2005) 722-728
48. Kim Y.H., Kim D.Y., Kim T.H., et al. Usefulness of magnetic resonance volumetric evaluation in predicting response to preoperative concurrent chemoradiotherapy in patients with resectable rectal cancer. Int J Radiat Oncol Biol Phys 62 3 (2005) 761-768
49. Maurer C.A., Z'Graggen K., Renzulli P., et al. Total mesorectal excision preserves male genital function compared with conventional rectal cancer surgery. Br J Surg 88 11 (2001) 1501-1505
50. Hojo K., Sawada T., and Moriya Y. An analysis of survival and voiding, sexual function after wide iliopelvic lymphadenectomy in patients with carcinoma of the rectum, compared with conventional lymphadenectomy. Dis Colon Rectum 32 2 (1989) 128-133
51. Kinn A.C., and Ohman U. Bladder and sexual function after surgery for rectal cancer. Dis Colon Rectum 29 1 (1986) 43-48
52. Koukouras D., Spiliotis J., Scopa C.D., et al. Radical consequence in the sexuality of male patients operated for colorectal carcinoma. Eur J Surg Oncol 17 3 (1991) 285-288
53. Pocard M., Zinzindohoue F., Haab F., et al. A prospective study of sexual and urinary function before and after total mesorectal excision with autonomic nerve preservation for rectal cancer. Surgery 131 4 (2002) 368-372
54. Kim N.K., Aahn T.W., Park J.K., et al. Assessment of sexual and voiding function after total mesorectal excision with pelvic autonomic nerve preservation in males with rectal cancer. Dis Colon Rectum 45 9 (2002) 1178-1185
55. Junginger T., Kneist W., and Heintz A. Influence of identification and preservation of pelvic autonomic nerves in rectal cancer surgery on bladder dysfunction after total mesorectal excision. Dis Colon Rectum 46 5 (2003) 621-628
56. Peeters K.C., Tollenaar R.A., Marijnen C.A., et al. Risk factors for anastomotic failure after total mesorectal excision of rectal cancer. Br J Surg 92 2 (2005) 211-216
57. Moran B.J., and Heald R.J. Risk factors for and management of anastomotic leakage in rectal surgery. Colorectal Dis 3 2 (2001) 135-137
58. Vignali A., Fazio V.W., Lavery I.C., et al. Factors associated with the occurrence of leaks in stapled rectal anastomoses: a review of 1014 patients. J Am Coll Surg 185 2 (1997) 105-113
59. Rullier E., Laurent C., Garrelon J.L., et al. Risk factors for anastomotic leakage after resection of rectal cancer. Br J Surg 85 3 (1998) 355-358
60. Eriksen M.T., Wibe A., Norstein J., et al. Anastomotic leakage following routine mesorectal excision for rectal cancer in a national cohort of patients. Colorectal Dis 7 1 (2005) 51-57
61. Zaheer S., Pemberton J.H., Farouk R., et al. Surgical treatment of adenocarcinoma of the rectum. Ann Surg 227 6 (1998) 800-811
62. Karanjia N.D., Corder A.P., Bearn P., et al. Leakage from stapled low anastomosis after total mesorectal excision for carcinoma of the rectum. Br J Surg 81 8 (1994) 1224-1226
63. Petersen S., Freitag M., Hellmich G., et al. Anastomotic leakage: impact on local recurrence and survival in surgery of colorectal cancer. Int J Colorectal Dis 13 4 (1998) 160-163
64. Bell S.W., Walker K.G., Rickard M.J., et al. Anastomotic leakage after curative anterior resection results in a higher prevalence of local recurrence. Br J Surg 90 10 (2003) 1261-1266
65. Walker K.G., Bell S.W., Rickard M.J., et al. Anastomotic leakage is predictive of diminished survival after potentially curative resection for colorectal cancer. Ann Surg 240 2 (2004) 255-259
66. Moran B., and Heald R. Anastomotic leakage after colorectal anastomosis. Semin Surg Oncol 18 3 (2000) 244-248
67. Dehni N., Schlegel R.D., Cunningham C., et al. Influence of a defunctioning stoma on leakage rates after low colorectal anastomosis and colonic J pouch-anal anastomosis. Br J Surg 85 8 (1998) 1114-1117
68. Gastinger I., Marusch F., Steinert R., et al. Protective defunctioning stoma in low anterior resection for rectal carcinoma. Br J Surg 92 9 (2005) 1137-1142
69. Hallbook O., Matthiessen P., Leinskold T., et al. Safety of the temporary loop ileostomy. Colorectal Dis 4 5 (2002) 361-364
70. Lacy A.M., Garcia-Valdecasas J.C., Delgado S., et al. Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial. Lancet 359 9325 (2002) 2224-2229
71. Morino M., and Giraudo G. Laparoscopic total mesorectal excision-the Turin experience. Recent Results Cancer Res 165 (2005) 167-179
72. Aziz O., Constantinides V., Tekkis P.P., et al. Laparoscopic versus open surgery for rectal cancer: a meta-analysis. Ann Surg Oncol 13 3 (2006) 413-424
73. Jayne D.G., Brown J.M., Thorpe H., et al. Bladder and sexual function following resection for rectal cancer in a randomized clinical trial of laparoscopic versus open technique. Br J Surg 92 9 (2005) 1124-1132
74. Quah H.M., Jayne D.G., Eu K.W., et al. Bladder and sexual dysfunction following laparoscopically assisted and conventional open mesorectal resection for cancer. Br J Surg 89 12 (2002) 1551-1556
75. Maurer CA. Colon cancer: resection standards. Tech Coloproctol 2004;8(Suppl 1):s29-32.
76. Barlehner E., Benhidjeb T., Anders S., et al. Laparoscopic resection for rectal cancer: outcomes in 194 patients and review of the literature. Surg Endosc 19 6 (2005) 757-766
77. Tsang W.W., Chung C.C., Kwok S.Y., et al. Laparoscopic sphincter-preserving total mesorectal excision with colonic J-pouch reconstruction: five-year results. Ann Surg 243 3 (2006) 353-358
78. Koch M., Kienle P., Antolovic D., et al. Is the lateral lymph node compartment relevant?. Recent Results Cancer Res 165 (2005) 40-45
79. Fujita S., Yamamoto S., Akasu T., et al. Lateral pelvic lymph node dissection for advanced lower rectal cancer. Br J Surg 90 12 (2003) 1580-1585
80. Ueno H., Mochizuki H., Hashiguchi Y., et al. Prognostic determinants of patients with lateral nodal involvement by rectal cancer. Ann Surg 234 2 (2001) 190-197
81. Takahashi T., Ueno M., Azekura K., et al. Lateral node dissection and total mesorectal excision for rectal cancer. Dis Colon Rectum 43 10 Suppl (2000) S59-S68
82. Hida J., Yasutomi M., Fujimoto K., et al. Does lateral lymph node dissection improve survival in rectal carcinoma? Examination of node metastases by the clearing method. J Am Coll Surg 184 5 (1997) 475-480
83. Koda K., Saito N., Oda K., et al. Evaluation of lateral lymph node dissection with preoperative chemo-radiotherapy for the treatment of advanced middle to lower rectal cancers. Int J Colorectal Dis 19 3 (2004) 188-194
84. Moriya Y., Sugihara K., Akasu T., et al. Importance of extended lymphadenectomy with lateral node dissection for advanced lower rectal cancer. World J Surg 21 7 (1997) 728-732
85. Moriya Y., Sugihara K., Akasu T., et al. Nerve-sparing surgery with lateral node dissection for advanced lower rectal cancer. Eur J Cancer 31A 7-8 (1995) 1229-1232
86. Mori T., Takahashi K., and Yasuno M. Radical resection with autonomic nerve preservation and lymph node dissection techniques in lower rectal cancer surgery and its results: the impact of lateral lymph node dissection. Langenbecks Arch Surg 383 6 (1998) 409-415
87. Watanabe T., Tsurita G., Muto T., et al. Extended lymphadenectomy and preoperative radiotherapy for lower rectal cancers. Surgery 132 1 (2002) 27-33
88. Moriya Y., Hojo K., Sawada T., et al. Significance of lateral node dissection for advanced rectal carcinoma at or below the peritoneal reflection. Dis Colon Rectum 32 4 (1989) 307-315
89. Moreira L.F., Hizuta A., Iwagaki H., et al. Lateral lymph node dissection for rectal carcinoma below the peritoneal reflection. Br J Surg 81 2 (1994) 293-296
90. Shimoyama M., Yamazaki T., Suda T., et al. Prognostic significance of lateral lymph node micrometastases in lower rectal cancer: an immunohistochemical study with CAM5.2. Dis Colon Rectum 46 3 (2003) 333-339
91. Ueno M., Oya M., Azekura K., et al. Incidence and prognostic significance of lateral lymph node metastasis in patients with advanced low rectal cancer. Br J Surg 92 6 (2005) 756-763
92. Maeda K., Maruta M., Utsumi T., et al. Bladder and male sexual functions after autonomic nerve-sparing TME with or without lateral node dissection for rectal cancer. Tech Coloproctol 7 1 (2003) 29-33
93. Sugihara K., Moriya Y., Akasu T., et al. Pelvic autonomic nerve preservation for patients with rectal carcinoma: oncologic and functional outcome. Cancer 78 9 (1996) 1871-1880
94. Nagawa H., Muto T., Sunouchi K., et al. Randomized, controlled trial of lateral node dissection vs. nerve-preserving resection in patients with rectal cancer after preoperative radiotherapy. Dis Colon Rectum 44 9 (2001) 1274-1280
95. Martling A.L., Holm T., Rutqvist L.E., et al. Effect of a surgical training programme on outcome of rectal cancer in the County of Stockholm: Stockholm Colorectal Cancer Study Group, Basingstoke Bowel Cancer Research Project. Lancet 356 9224 (2000) 93-96
96. Bulow S., Christensen I.J., Harling H., et al. Danish TME Study Group; RANX05 Colorectal Cancer Study Group. Recurrence and survival after mesorectal excision for rectal cancer. Br J Surg 90 8 (2003) 974-980
97. Law W.L., and Chu K.W. Anterior resection for rectal cancer with mesorectal excision: a prospective evaluation of 622 patients. Ann Surg 240 2 (2004) 260-268
98. Chiappa A., Biffi R., Zbar A.P., et al. Results of treatment of distal rectal carcinoma since the introduction of total mesorectal excision: a single unit experience, 1994-2003. Int J Colorectal Dis 20 3 (2005) 221-230
99. Piso P., Dahlke M.H., Mirena P., et al. Total mesorectal excision for middle and lower rectal cancer: a single institution experience with 337 consecutive patients. J Surg Oncol 86 3 (2004) 115-121