Antifungal treatment in sarcoidosis-A pilot intervention trial

Respiratory Medicine

Volumn 101, Issue 4, 2007, Pages 774-778

  Tercelj, Marjeta ^a   Rott, Tomaz ^b   Rylander, Ragnar ^c  

^a UNIVERSITY MEDICAL CENTRE LJUBLJANA   (Slovenia)

^b UNIVERSITY OF LJUBLJANA   (Slovenia)

^c BioFact Environmental Health Research Center   (Sweden)

Author keywords

(1 3) d glucan; Fungi; Hypersensitivity; Inflammation; Sarcoidosis

Indexed keywords

ANTIFUNGAL AGENT; CORTICOSTEROID; FLUCONAZOLE; ITRACONAZOLE; KETOCONAZOLE; PREDNISOLONE;

ADULT; AGED; ARTICLE; ASPERGILLOSIS; ASPERGILLUS; CANDIDA; CANDIDIASIS; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DRUG DOSE REDUCTION; DRUG EFFICACY; FEMALE; FOLLOW UP; HUMAN; LUNG BIOPSY; LUNG DIFFUSION CAPACITY; LUNG FUNCTION TEST; LUNG INFILTRATE; LUNG SARCOIDOSIS; MALE; MONOTHERAPY; MYCOSIS; PILOT STUDY; PRIORITY JOURNAL; SCORING SYSTEM; THORAX RADIOGRAPHY;

ADRENAL CORTEX HORMONES; ADULT; AGED; ANTIFUNGAL AGENTS; DRUG THERAPY, COMBINATION; FEMALE; FLUCONAZOLE; HUMANS; ITRACONAZOLE; KETOCONAZOLE; MALE; MIDDLE AGED; PILOT PROJECTS; SARCOIDOSIS; TREATMENT OUTCOME;

EID: 33847295812     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rmed.2006.08.005     Document Type: Article

References (17)

1. Martin II W.J., Iannuzzi M.C., Gail D.B., et al. Future directions in sarcoidosis research. Summary of an NHLBI working group. Am J Resp Crit Care Med 170 (2004) 567-571
2. Newman L.S., Maier L.A., and Rose C.S. Sarcoidosis. N Engl J Med 336 (1997) 1224-1234
3. duBois R.M., Goh N., McGrath D., et al. Is there a role for microorganisms in the pathogenesis of sarcoidosis?. J Int Med 253 (2003) 4-17
4. Ortiz C., Hodgson M., McNally D., et al. Sarcoidosis and exposure to occupational and environmental agents. In: Johanning E. (Ed). Bioaerosols, fungi and mycotoxins; health effects, assessment, prevention and control (1999), Eastern New York Occupational and Environmental Health Centre, Albany, New York, USA 476-481
5. Kucera G.P., Rybicki B.A., Kirkey K.L., et al. Occupational risk factors for sarcoidosis in African-American siblings. Chest 123 (2003) 1527-1535
6. Newman L.S., Rose C.S., Bresnitz E.A., et al. A case-control etiological study of sarcoidosis-environmental and occupational risk factors. Am J Respir Crit Care Med 170 (2004) 1324-1330
7. American Thoracic Society. Statement on sarcoidosis. Am J Respir Crit Care Med 160 (1999) 736-755
8. Ward G.W., Woodfolk J.A., Hayden M.L., et al. Treatment of late-onset asthma with fluconazole. J Allergy Clin Immunol 104 (1999) 146-151
9. Ho L.-P., Urban B.C., Thickett D.R., et al. Deficiency of a subset of T-cells with immunoregulatory properties in sarcoidosis. The Lancet 365 (2005) 1062-1072
10. Ota M., Amakawa R., Uehira K., et al. Involvement of dendritic cells in sarcoidosis. Thorax 59 (2004) 408-413
11. Rylander R. Role of endotoxin and glucan for the development of granulomatous disease in the lung. Sarcoidosis 6 (1989) 26-27
12. Rylander R. (1→3)-β-d-glucan in the environment: a risk assessment. In: Young S.-H., and Castranova V. (Eds). Toxicology of (1→3)-β-glucans: glucans as a marker for fungal exposure (1995), CRC Press, Boca Raton, FA 53-64
13. Johnson K.J., Glovsky M., and Schrier D. Pulmonary granulomatous vasculitis induced in rats by treatment with glucan. Am J Pathol 114 (1984) 515-516
14. Wan G.-H., Li C.-S., Guo S.-P., et al. An airborne mold-derived product, (1→3)-β-d-glucan, potentiates airway allergic responses. Eur J Immunol 9 (1999) 2491-2497
15. Ormstad H., Groeng E.C., Lovik M., et al. The fungal wall component beta.1, 3-glucan has an adjuvant effect on the allergic response to ovalbumin in mice. J Toxicol Environ Health 61 (2000) 55-67
16. American Thoracic Society, European Respiratory Society, World Association of Sarcoidosis and other granulomatous disease. Statement on sarcoidosis. Am J Resp Crit Care Med 160 (1990) 736-755
17. Curtis J.R., and Borson S. Examining the link between sarcoidosis and depression. Am J Resp Crit Care Med 163 (2001) 306-308