Bolevenine, a toxic protein from the Japanese toadstool Boletus venenatus

Phytochemistry

Volumn 68, Issue 6, 2007, Pages 893-898

  Matsuura, Masanori ^a   Yamada, Mina ^a   Saikawa, Yoko ^a   Miyairi, Kazuo ^b   Okuno, Toshikatsu ^b   Konno, Katsuhiro ^c   Uenishi, Jun'ichi ^d   Hashimoto, Kimiko ^d   Nakata, Masaya ^a  

^a KEIO UNIVERSITY   (Japan)

^b HIROSAKI UNIVERSITY   (Japan)

^c INSTITUTO BUTANTAN   (Brazil)

^d KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Boletaceae; Boletus venenatus; Bolevenine; Mushroom poisoning; Toxic protein; Trimeric protein

Indexed keywords

BOLESATINE PROTEIN, BOLETUS SATANAS; FUNGAL PROTEIN; MYCOTOXIN; UNCLASSIFIED DRUG;

AGARICALES; AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CHEMISTRY; FEMALE; GEL CHROMATOGRAPHY; ION EXCHANGE CHROMATOGRAPHY; ISOELECTRIC FOCUSING; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; MOUSE; PH; POLYACRYLAMIDE GEL ELECTROPHORESIS; TOXICITY TESTING;

AGARICALES; AMINO ACID SEQUENCE; ANIMALS; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, ION EXCHANGE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; FUNGAL PROTEINS; HYDROGEN-ION CONCENTRATION; ISOELECTRIC FOCUSING; MICE; MOLECULAR SEQUENCE DATA; MYCOTOXINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TOXICITY TESTS;

BASIDIOMYCOTA; BOLETACEAE; BOLETUS; BOLETUS SATANAS; MUS;

EID: 33847284515     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phytochem.2006.11.037     Document Type: Article

References (16)

1. Basset L., Badoc A., Deffieux G., Counord J., Andrieux M., and Creppy E.E. Effets de la bolesatine, toxine proteique extraite du bolet satan sur des cellules en culture. Bull. Soc. Pharm. Bordeaux 130 (1991) 39-45
2. Basset L., Ennamany R., Portail J.P., Kretz O., Deffieux G., Badoc A., Guillemain B., and Creppy E.E. Effects of bolesatine on a cell line from the SP2/O thymic lymphosarcoma. Toxicology 103 (1995) 121-125
3. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
4. 5dC variation in Vero cells related to inhibition of cell growth. Cell Biol. Toxicol. 11 (1995) 347-354
5. Ennamany R., Bingen A., Creppy E.E., Kretz O., Gut J.P., Dubuisson L., Balabaud C., Sage P.B., and Kirn A. Aspirin and heparin prevent hepatic blood stasis and thrombosis induced by the toxic glycoprotein bolesatine in mice. Hum. Exp. Toxicol. 17 (1998) 620-624
6. Gachet C., Ennamany R., Kretz O., Ohlmann P., Krause C., Creppy E.E., Dirheimer G., and Cazenave J.P. Bolesatine induces agglutination of rat platelets and human erythrocytes and platelets in vitro. Hum. Exp. Toxicol. 15 (1996) 26-29
7. Kretz O., Creppy E.E., Boulanger Y., and Dirheimer G. Purification and some properties of bolesatine, a protein inhibiting in vitro protein synthesis, from the mushroom Boletus satanas Lenz (Boletaceae). Arch. Toxicol. Suppl. 13 (1989) 422-427
8. Kretz O., Creppy E.E., and Dirheimer G. Disposition of the toxic protein, in rats: its resistance to proteolytic enzymes. Xenobiotica 21 (1991) 65-73
9. Kretz O., Creppy E.E., and Dirheimer G. Characterization of bolesatine, a toxic protein from the mushroom Boletus satanas Lenz and its effects on kidney cells. Toxicology 66 (1991) 213-224
10. Kretz O., Barbieri L., Creppy E.E., and Dirheimer G. Inhibition of protein synthesis in liver and kidney of mice by bolesatine: mechanistic approaches to the mode of action at the molecular level. Toxicology 73 (1992) 297-304
11. Kretz O., Reinbolt J., Creppy E.E., and Dirheimer G. Properties of bolesatine, a translational inhibitor from Boletus satanas Lenz. Amino-terminal sequence determination and inhibition of rat mitochondrial protein synthesis. Toxicol. Lett. 64/65 (1992) 763-766
12. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
13. Miyairi K., Ogasawara A., Tonouchi A., Hosokawa K., Kudou M., and Okuno T. Low-molecular-weight pectate lyase from Streptomyces thermocarboxydus. J. Appl. Glycosci. 51 (2004) 1-7
14. Nagasawa E. A new poisonous species of Boletus from Japan. Rep. Tottori Mycol. Inst. 33 (1995) 1-6
15. Razanamparany J.L., Creppy E.E., Perreau-Bertrand J., Boulanger Y., and Dirheimer G. Purification and characterization of bolaffinine, a toxic protein from Boletus affinis Peck (Boletaceae). Biochimie 68 (1986) 1217-1223
16. Watanabe R., Kita M., and Uemura D. A novel dipeptide, N-γ-glutamyl boletine, and a cyclic iminium toxin from the mushroom Tylopilus sp. (Boletaceae). Tetrahedron Lett. 43 (2002) 6501-6504