A novel dipeptide, N-γ-glutamyl boletine, and a cyclic iminium toxin from the mushroom Tylopilus sp. (Boletaceae)

Tetrahedron Letters

Volumn 43, Issue 37, 2002, Pages 6501-6504

  Watanabe, Reiko ^a   Kita, Masaki ^a   Uemura, Daisuke ^a  

^a NAGOYA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 BUTYL 1 AZACYCLOHEXENEIMINIUM; AMINO ACID; ANTIINFECTIVE AGENT; DIPEPTIDE; IMINE; KETONE DERIVATIVE; N GAMMA GLUTAMYLBOLETINE; PIPERIDINE DERIVATIVE; TOXIN; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ARTICLE; BIOSYNTHESIS; CHEMICAL ANALYSIS; CONTROLLED STUDY; HYDROLYSIS; MOUSE; MOUSE STRAIN; MUSHROOM; NONHUMAN; PROTEIN ISOLATION; SPECTROSCOPY; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

BASIDIOMYCOTA; BOLETACEAE; TYLOPILUS;

EID: 0037048498     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(02)01495-8     Document Type: Article

References (13)

1. Lee S.-J., Yun B.-S., Cho D.-H., Yoo I.-D. J. Antibiot. 52:2000;998-1006.
2. Takaishi Y., Ohashi T., Tomimatsu T. Phytochemistry. 28:1989;945-947.
3. Wu S.-H., Luo X.-D., Ma Y.-B., Liu J.-K., Wu D.-G., Zhao B., Lu Y., Zheng Q.-T. J. Nat. Prod. 63:2000;534-536.
4. Liu J. Heterocycles. 57:2002;157-167.
5. 2O containing 0.1% NaCl; flow rate, 5.0 mL/min; detection at 215 nm. Desalting was achieved by the column chromatography (TSK G-3000S; eluent, 50% aqueous EtOH).
6. 4 (pH 2.0); flow rate, 0.4 mL/min; detection at 200 nm.
7. Tong G., Perich W., Johns R.B. Aust. J. Chem. 45:1992;1225-1240.
8. Mikolajczyk M., Mikina M. J. Org. Chem. 59:1994;6760-6765.
9. Vasil'ev A., Engman L. J. Org. Chem. 65:2000;2151-2162.
10. 30 -0.56° (c 0.33, MeOH).
11. Hoffman V.H., Buntain G.A. J. Org. Chem. 53:1988;3316-3321.
12. Leete E. Acc. Chem. Res. 4:1971;100-107.
13. Terashima T., Idaka E., Kishi Y., Goto T. J. Chem. Soc., Chem. Commun. 1973;75-76.