Mechanism of Ad5 vaccine immunity and toxicity: Fiber shaft targeting of dendritic cells

PLoS Pathogens

Volumn 3, Issue 2, 2007, Pages 0239-0245

  Cheng, Cheng ^a   Gall, Jason G D ^b   Kong, Wing Pui ^a   Sheets, Rebecca L ^a   Gomez, Phillip L ^a   King, C Richter ^b   Nabel, Gary J ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b GENVEC INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; INTEGRIN RECEPTOR; VIRUS RECEPTOR; VIRUS VACCINE; ADENOVIRUS RECEPTOR; ARGINYL GLYCYL ASPARTIC ACID DIRECTED CELL ADHESION RECEPTOR; ARGINYL-GLYCYL-ASPARTIC ACID DIRECTED CELL ADHESION RECEPTOR; IMMUNOGLOBULIN RECEPTOR; RECEPTOR; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; COXSACKIE VIRUS; DENDRITIC CELL; EPITHELIUM CELL; FEMALE; FEVER; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNITY; IMMUNOCOMPETENT CELL; IMMUNOGENICITY; MONONUCLEAR CELL; MOUSE; MUTATION; NONHUMAN; SAFETY; VIRUS REPLICATION; ADENOVIRUS; ANIMAL; BAGG ALBINO MOUSE; DOSE RESPONSE; GENE VECTOR; GENETIC TRANSDUCTION; GENETICS; IMMUNOLOGY; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; RABBIT; VIROLOGY; VIRUS INFECTION;

ADENOVIRIDAE; COXSACKIEVIRUS; EBOLA VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; MUS;

ADENOVIRIDAE; ADENOVIRIDAE INFECTIONS; ANIMALS; DENDRITIC CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENETIC VECTORS; HUMANS; MICE; MICE, INBRED BALB C; MUTATION; RABBITS; RECEPTORS, IMMUNOLOGIC; RECEPTORS, PEPTIDE; RECEPTORS, VIRUS; TRANSDUCTION, GENETIC; VIRAL PROTEINS; VIRAL VACCINES; VIRUS REPLICATION;

EID: 33847264371     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.0030025     Document Type: Article

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