Interest of a 48 h systematic paralysis at the early phase, in patients presenting with ARDS. The ACURASYS study. Protocol presentation;Intérêt d'une curarisation systématique précoce de 48 heures sur le pronostic des patients présentant un syndrome de détresse respiratoire aiguë. Étude ACURASYS. Présentation du protocole

Reanimation

Volumn 16, Issue 1, 2007, Pages 88-95

  Papazian, L ^a   Forel, J M ^a   Morange, S ^a   Barrau, K ^b   Penot Ragon, C ^a  

^a HÔPITAL SAINTE MARGUERITE   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

Author keywords

Acute respiratory distress syndrome; Mechanical ventilation; Mortality; Neuromuscular blocking agent; Randomized controlled trial

Indexed keywords

CYTOKINE; NEUROMUSCULAR BLOCKING AGENT;

ADULT RESPIRATORY DISTRESS SYNDROME; ARTIFICIAL VENTILATION; CLINICAL FEATURE; CLINICAL PROTOCOL; DRUG INDICATION; HUMAN; INTENSIVE CARE UNIT; LUNG LAVAGE; MORTALITY; PARALYSIS; SHORT SURVEY;

EID: 33847251937     PISSN: 16240693     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reaurg.2007.01.001     Document Type: Short Survey

References (22)

1. Murray M.J., Cowen J., DeBlock H., Erstad B., Gray Jr. A.W., Tescher A.N., et al. Clinical practice guidelines for sustained neuromuscular blockade in the adult critically ill patient. Crit. Care Med. 30 (2002) 142-156
2. Dreyfuss D., Soler P., Basset G., and Saumon G. High inflation pressure pulmonary edema. Respective effects of high airway pressure, high tidal volume, and positive end-expiratory pressure. Am. Rev. Respir. Dis. 137 (1988) 1159-1164
3. Pinhu L., Whitehead T., Evans T., and Griffiths M. Ventilator-associated lung injury. Lancet 361 (2003) 332-340
4. Tremblay L., Valenza F., Ribeiro S.P., Li J., and Slutsky A.S. Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model. J. Clin. Invest. 99 (1997) 944-952
5. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N. Engl. J. Med. 342 (2000) 1301-1308
6. Hansen-Flaschen J.H., Brazinsky S., Basile C., and Lanken P.N. Use of sedating drugs and neuromuscular blocking agents in patients requiring mechanical ventilation for respiratory failure. A national survey. JAMA 266 (1991) 2870-2875
7. Hedenstierna G., Strandberg A., Brismar B., Lundquist H., Svensson L., and Tokics L. Functional residual capacity, thoracoabdominal dimensions, and central blood volume during general anesthesia with muscle paralysis and mechanical ventilation. Anesthesiology 62 (1985) 247-254
8. Rehder K., Sessler A.D., and Rodarte J.R. Regional intrapulmonary gas distribution in awake and anesthetized-paralyzed man. J. Appl. Physiol. 42 (1977) 391-402
9. Tokics L., Hedenstierna G., Svensson L., Brismar B., Cederlund T., Lundquist H., et al. V/Q distribution and correlation to atelectasis in anesthetized paralyzed humans. J. Appl. Physiol. 81 (1996) 1822-1833
10. Gainnier M., Roch A., Forel J.M., Thirion X., Arnal J.M., Donati S., et al. Effect of neuromuscular blocking agents on gas exchange in patients presenting with acute respiratory distress syndrome. Crit. Care Med. 32 (2004) 113-119
11. Coggeshall J.W., Marini J.J., and Newman J.H. Improved oxygenation after muscle relaxation in adult respiratory distress syndrome. Arch. Intern. Med. 145 (1985) 1718-1720
12. Westbrook P.R., Stubbs S.E., Sessler A.D., Rehder K., and Hyatt R.E. Effects of anesthesia and muscle paralysis on respiratory mechanics in normal man. J. Appl. Physiol. 34 (1973) 81-86
13. Conti G., Vilardi V., Rocco M., DeBlasi R.A., Lappa A., Bufi M., et al. Paralysis has no effect on chest wall and respiratory system mechanics of mechanically ventilated, sedated patients. Intensive Care Med. 21 (1995) 808-812
14. Bishop M.J. Arterial oxygenation after pancuronium paralysis. J. Pediatr. 99 (1981) 325-326
15. Dreyfuss D., and Saumon G. Role of tidal volume, FRC, and end-inspiratory volume in the development of pulmonary edema following mechanical ventilation. Am. Rev. Respir. Dis. 148 (1993) 1194-1203
16. Chiumello D., Pristine G., and Slutsky A.S. Mechanical ventilation affects local and systemic cytokines in an animal model of acute respiratory distress syndrome. Am. J. Respir. Crit. Care Med. 160 (1999) 109-116
17. Tutor J.D., Mason C.M., Dobard E., Beckerman R.C., Summer W.R., and Nelson S. Loss of compartmentalization of alveolar tumor necrosis factor after lung injury. Am. J. Respir. Crit. Care Med. 149 (1994) 1107-1111
18. Ranieri V.M., Suter P.M., Tortorella C., De Tullio R., Dayer J.M., Brienza A., et al. Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: a randomized controlled trial. JAMA 282 (1999) 54-61
19. Forel J.M., Roch A., Marin V., Michelet P., Demory D., Blache J.L., et al. Neuromuscular blocking agents decrease inflammatory response in patients presenting with acute respiratory distress syndrome. Crit. Care Med. 34 (2006) 2749-2757
20. Bernard G.R., Artigas A., Brigham K.L., Carlet J., Falke K., Hudson L., et al. Report of the American-European Consensus conference on acute respiratory distress syndrome: definitions, mechanisms, relevant outcomes, and clinical trial coordination. Consensus Committee. J. Crit. Care 9 (1994) 72-81
21. De Jonghe B., Sharshar T., Lefaucheur J.P., Authier F.J., Durand-Zaleski I., Boussarsar M., et al. Paresis acquired in the intensive care unit: a prospective multicenter study. JAMA 288 (2002) 2859-2867
22. Brun-Buisson C., Minelli C., Bertolini G., Brazzi L., Pimentel J., Lewandowski K., et al. Epidemiology and outcome of acute lung injury in European intensive care units. Results from the ALIVE study. Intensive Care Med. 30 (2004) 51-61