Hypertension: The kidney is the culprit even in the absence of kidney disease

Kidney International

Volumn 71, Issue 5, 2007, Pages 371-372

  Ritz, Eberhard ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II;

EDITORIAL; GLOMERULUS; HUMAN; HYPERTENSION; KIDNEY DISEASE; KIDNEY DONOR; KIDNEY FAILURE; KIDNEY GRAFT; KIDNEY TRANSPLANTATION; NEPHRON; ORGANOGENESIS; PRIORITY JOURNAL; PUBLIC HEALTH; SODIUM ABSORPTION; VASOCONSTRICTION;

BLOOD PRESSURE; HUMANS; HYPERTENSION; KIDNEY; KIDNEY DISEASES; PUBLIC HEALTH;

EID: 33847241207     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/sj.ki.5002142     Document Type: Editorial

References (22)

1. Kearney PM, Whelton M, Reynolds K et al. Global burden of hypertension: analysis of worldwide data. Lancet 2005; 365: 217-223.
2. Lopez AD, Mathers CD, Ezzati M et al. Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet 2006; 367: 1747-1757.
3. Chobanian AV, Bakris GL, Black HR et al. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA 2003; 289: 2560-2572.
4. Lewington S, Clarke R, Qizilbash N et al. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002; 360: 1903-1913.
5. Hsu CY. Does treatment of non-malignant hypertension reduce the incidence of renal dysfunction? A meta-analysis of 10 randomised, controlled trials. J Hum Hypertens 2001; 15: 99-106.
6. Bright R. Reports of Medical Cases with a View of Illustrating the Symptoms and Cure of Diseases. Longman: London, 1827.
7. Guyton AC. Renal function curve: a key to understanding the pathogenesis of hypertension. Hypertension 1987; 10: 1-6.
8. Curtis JJ, Luke RG, Dustan HP et al. Remission of essential hypertension after renal transplantation. N Engl J Med 1983; 309: 1009-1015.
9. Lifton RP. Genetic dissection of human blood pressure variation: common pathways from rare phenotypes. Harvey Lect 2004; 100: 71-101.
10. Oliver J. Nephrons and Kidney. Harper and Row: New York, 1968, pp 35-38.
11. Barker DJ, Osmond C, Golding J et al. Growth in utero, blood pressure in childhood and adult life, and mortality from cardiovascular disease. BMJ 1989; 298: 564-567.
12. Brenner BM, Garcia DL, Anderson S. Glomeruli and blood pressure. Less of one, more the other? Am J Hypertens 1988; 1: 335-347.
13. Keller G, Zimmer G, Mall G et al. Nephron number in patients with primary hypertension. N Engl J Med 2003; 348: 101-108.
14. Hoy WE, Hughson MD, Bertram JF et al. Nephron number, hypertension, renal disease, and renal failure. J Am Soc Nephrol 2005; 16: 2557-2564.
15. Hoy WE, Hughson MD, Singh GR et al. Reduced nephron number and glomerulomegaly in Australian Aborigines: a group at high risk for renal disease and hypertension. Kidney Int 2006; 70: 104-110.
16. Fehrman-Ekholm I, Duner F, Brink B et al. No evidence of accelerated loss of kidney function in living kidney donors: results from a cross-sectional follow-up. Transplantation 2001; 72: 444-449.
17. Woods LL, Weeks DA, Rasch R. Hypertension after neonatal uninephrectomy in rats precedes glomerular damage. Hypertension 2001; 38: 337-342.
18. Manning J, Beutler K, Knepper MA, Vehaskari VM. Upregulation of renal BSC1 and TSC in prenatally programmed hypertension. Am J Physiol Renal Physiol 2002; 283: F202-F206.
19. Vehaskari VM, Stewart T, Lafont D et al. Kidney angiotensin and angiotensin receptor expression in prenatally programmed hypertension. Am J Physiol Renal Physiol 2004; 287: F262-F267.
20. Houang M, Morineau G, le Bouc Y et al. The cortisolcortisone shuttle in children born with intrauterine growth retardation. Pediatr Res 1999; 46: 189-193.
21. Alexander BT, Hendon AE, Ferril G, Dwyer TM. Renal denervation abolishes hypertension in low-birth-weight offspring from pregnant rats with reduced uterine perfusion. Hypertension 2005; 45: 754-758.
22. Klahr S. The kidney in hypertension: villain and victim. N Engl J Med 1989; 320: 731-733.