Sugammadex reversal of rocuronium-induced neuromuscular blockade: A comparison with neostigmine-glycopyrrolate and edrophonium-atropine

Anesthesia and Analgesia

Volumn 104, Issue 3, 2007, Pages 569-574

  Sacan, Ozlem ^a   White, Paul F ^a   Tufanogullari, Burcu ^a   Klein, Kevin ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATROPINE; CHOLINESTERASE INHIBITOR; DESFLURANE; EDROPHONIUM; FENTANYL; GLYCOPYRRONIUM BROMIDE; MIDAZOLAM; NEOSTIGMINE; PROPOFOL; REMIFENTANIL; ROCURONIUM; SUGAMMADEX;

ADULT; AGED; ARTICLE; BLOOD PRESSURE MONITORING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEMOGRAPHY; DIZZINESS; DROWSINESS; DRUG EFFICACY; DRUG SAFETY; ELECTIVE SURGERY; FEMALE; HEART RATE; HOSPITAL DISCHARGE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; NAUSEA; NEUROMUSCULAR BLOCKING; PATIENT MONITORING; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STANDARD; VOMITING; XEROSTOMIA;

ADJUVANTS, ANESTHESIA; AGED; ANDROSTANOLS; ATROPINE; CHOLINESTERASE INHIBITORS; EDROPHONIUM; FEMALE; GAMMA-CYCLODEXTRINS; GLYCOPYRROLATE; HUMANS; MALE; MIDDLE AGED; NEOSTIGMINE; NEUROMUSCULAR BLOCKADE; NEUROMUSCULAR NONDEPOLARIZING AGENTS; PROSPECTIVE STUDIES; TIME FACTORS;

EID: 33847193874     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ane.0000248224.42707.48     Document Type: Article

References (15)

1. Kim KS, Lew SH, Cho HY, Cheong MA. Residual paralysis induced by either vecuronium or rocuronium after reversal with pyridostigmine. Anesth Analg 2002;95:1656-60.
2. Caldwell JE. Reversal or residual neuromuscular block with neostigmine at one to four hours after a single intubating dose of vecuronium. Anesth Analg 1995;80:1168-74.
3. Hunter JM, Flockton EA. The doughnut and the hole: a new pharmacological concept for anaesthetists. Br J Anaesth 2006;97:123-6.
4. Gijsenbergh F, Ramael S, Houwing N, van Iersel T. First human exposure of Org 25969, a novel agent to reverse the action of rocuronium bromide. Anesthesiology 2005;103:695-703.
5. Shields M, Giovannelli M, Mirakhur RK, et al. Org 25969 (sugammadex), a selective relaxant binding agent for antagonism of prolonged rocuronium-induced neuromuscular block. Br J Anaesth 2006;96:36-43.
6. Sorgenfrei IF, Norrild K, Larsen PB, et al. Reversal of rocuronium-induced neuromuscular block by the selective relaxant binding agent sugammadex. A dose-finding and safety study. Anesthesiology 2006;104:667-74.
7. Kopman AF, Zank LM, Ng J, Neuman GG. Antagonism of cisatracurium and rocuronium block at a tactile train-of-four count of 2: should quantitative assessment of neuromuscular function be mandatory? Anesth Analg 2004;98:102-6.
8. Tramer MR, Fuchs-Buder T. Omitting antagonism of neuromuscular block: effect on postoperative nausea and vomiting and risk of residual paralysis. A systematic review. Br J Anaesth 1999;82:379-86.
9. Lovstad RZ, Thagaard KS, Berner NS, Raeder JC. Neostigmine 50 μg/kg with glycopyrrolate increases postoperative nausea in women after laparoscopic gynaecological surgery. Acta Anaesthesiol Scand 2001;45:495-500.
10. Ding Y, Fredman B, White PF. Use of mivacurium during laparoscopic surgery: effect of reversal drugs on postoperative recovery. Anesth Analg 1994;78:450-4.
11. Lovstad RZ, Thagaard KS, Berner NS, Raeder J. Neostigmine 50 μg/kg with glycopyrrolate increases postoperative nausea in women after laparoscopic gynaecological surgery. Acta Anaesthesiol Scand 2001;45:495-500.
12. Naguib M, Abdulatif M, al-Ghamdi A. Dose-response relationships for edrophonium and neostigmine antagonism of rocuronium bromide (ORG 9426)-induced neuromuscular blockade. Anesthesiology 1993;79:739-45.
13. Epemolu O, Bom A, Hope F, Mason R. Reversal of neuromuscular blockade and simultaneous increase in plasma rocuronium concentration after the intravenous infusion of the novel reversal agent Org 25969. Anesthesiology 2003;99:632-7.
14. Kopman AF. Sugammadex: a revolutionary approach to neuromuscular antagonism. Anesthesiology 2006;104:631-3.
15. Song D, White PF. Remifentanil as an adjuvant during desflurane anesthesia facilitates early recovery after ambulatory surgery. J Clin Anesth 1999;11:364-7.