Understanding post-spaceflight orthostatic intolerance - A simulation study

Computers in Cardiology

Volumn 32, Issue , 2005, Pages 631-634

  Heldt, T ^a   Mark, R G ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; COMPUTATIONAL METHODS; COMPUTER SIMULATION; FEEDBACK; MATHEMATICAL MODELS; SPACE FLIGHT;

BLOOD PRESSURE; COMPUTATIONAL MODEL; HEMODYNAMIC RESPONSE; ORTHOSTATIC INTOLERANCE; ORTHOSTATIC STRESS;

CARDIOVASCULAR SYSTEM;

EID: 33847162840     PISSN: 02766574     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/CIC.2005.1588180     Document Type: Conference Paper

References (8)

1. Buckey J, Lane L, Levine J, Watenpaugh D, Wright S, Moore W, Gaffney F, Blomqvist C. Orthostatic intolerance after spaceflight. J Appl Physiol 1996;81(1):7-18.
2. Meek J, Reyes C, Perez S, Goldberger A, Ziegler M. Marked exacerbation of orthostatic intolerance after long- vs. shortduration spaceflight in veteran astronauts. Psychosom Med 2001;63(6):865-873.
3. Convertino V. Mechanisms of microgravity induced orthostatic intolerance: implications for effective countermeasures. J Gravit Physiol 2002;9(2):1-14.
4. Heldt T, Shim E, Kamm R, Mark R. Computational modeling of cardiovascular response to orthostatic stress. J Appl Physiol 2002;92(3):1239-1254.
5. Smith J, Hughes C, Ptacin M, Barney J, Tristani F, Ebert TJ. The effect of age on hemodynamic response to graded postural stress in normal men. Journal of Gerontology 1987; 42(4):406-411.
6. Waters W, Ziegler M, Meek J. Postspaceflight orthostatic hypotension occurs mostly in women and is predicted by low vascular resistance. J Appl Physiol 2002;2(92):596-594.
7. 1- adrenergic receptor responses before flight and central autonomic dysregulation post-flight. Am J Physiol 2004;286(4):H1486-H1495.
8. Platts S, Ziegler M, Waters W, Mitchell B, Meek J. Midodrine prescribed to improve recurrent post-spaceflight orthostatic hypotension. Aviat Space Enviro Med 2004; 75(6):554-556.