Relation of body mass and sex steroid hormone levels to hot flushes in a sample of mid-life women

Climacteric

Volumn 10, Issue 1, 2007, Pages 27-37

  Schilling, C ^a   Gallicchio, L ^b   Miller, S R ^c   Langenberg, P ^a   Zacur, H ^c   Flaws, J A ^a,d  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b MERCY MEDICAL CENTER   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Androgen; Body mass index; Estrogen; Hot flushes; Menopause

Indexed keywords

ANDROSTENEDIONE; ESTRADIOL; ESTRONE; PRASTERONE SULFATE; PROGESTERONE; SEX HORMONE; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE;

ADULT; AGE DISTRIBUTION; ANDROGEN BLOOD LEVEL; ARTICLE; BLOOD SAMPLING; BODY MASS; BODY WEIGHT; CONTROLLED STUDY; ESTROGEN BLOOD LEVEL; FEMALE; HORMONE DETERMINATION; HOT FLUSH; HUMAN; MAJOR CLINICAL STUDY; MENSTRUAL CYCLE; OBESITY; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; PROTEIN BLOOD LEVEL; QUESTIONNAIRE; RACE DIFFERENCE; SMOKING;

BODY MASS INDEX; FEMALE; GONADAL STEROID HORMONES; HOT FLASHES; HUMANS; MENOPAUSE; MIDDLE AGED; OBESITY; REGRESSION ANALYSIS; SEX HORMONE-BINDING GLOBULIN;

EID: 33847104993     PISSN: 13697137     EISSN: 14730804     Source Type: Journal    
DOI: 10.1080/13697130601164755     Document Type: Article

References (42)

1. Oldenhave A, Jaszmann LJ, Haspels AA, Everaerd WT. Impact of climacteric on well-being. A survey based on 5213 women 39 to 60 years old. Am J Obstet Gynecol 1993;168:772-80
2. Birge SJ. Hormones and the aging brain. Geriatrics 1998;53:S28-30
3. Avis NE, Crawford S, Stellato R, Longcope C. Longitudinal study of hormone levels and depression among women transitioning through menopause. Climacteric 2001;4:243-9
4. Schwingl PJ, Hulka BS, Harlow SD. Risk factors for menopausal hot flashes. Obstet Gynecol 1994;84:29-34
5. Freeman EW, Sammel MD, Grisso JA, Battistini M, Garcia-Espagna B, Hollander L. Hot flashes in the late reproductive years: risk factors for African American and Caucasian women. J Womens Health Gend Based Med 2001;10:67-76
6. Hyde Riley E, Inui TS, Kleinman K, Connelly MT. Differential association of modifiable health behaviors with hot flashes in perimenopausal and postmenopausal women. J Gen Intern Med 2004;19:740-6
7. Gallicchio L, Visvanathan K, Miller SR, et al. Body mass, estrogen levels, and hot flashes in midlife women. Am J Obstet Gynecol 2005;193:1353-60
8. den Tonkelaar I, Seidell JC, van Noord PA. Obesity and fat distribution in relation to hot flashes in Dutch women from the DOM-project. Maturitas 1996;23:301-5
9. Whiteman MK, Staropoli CA, Langenberg PW, McCarter RJ, Kjerulff KH, Flaws JA. Smoking, body mass, and hot flashes in midlife women. Obstet Gynecol 2003;101:264-72
10. Gold EB, Sternfeld B, Kelsey JL, et al. Relation of demographic and lifestyle factors to symptoms in a multi-racial/ethnic population of women 40-55 years of age. Am J Epidemiol 2000;152:463-73
11. Whiteman MK, Staropoli CA, Benedict JC, Borgeest C, Flaws JA. Risk factors for hot flashes in midlife women. J Womens Health 2003;12:459-72
12. Visvanathan K, Gallicchio L, Schilling C, et al. Cytochrome gene polymorphisms, serum estrogens, and hot flushes in midlife women. Obstet Gynecol 2005;106:1372-81
13. Gold EB, Block G, Crawford S, et al. Lifestyle and demographic factors in relation to vasomotor symptoms: baseline results from the Study of Women's Health Across the Nation. Am J Epidemiol 2004;159:1189-99
14. Randolph JF Jr, Sowers M, Gold EB, et al. Reproductive hormones in the early menopausal transition: relationship to ethnicity, body size, and menopausal status. J Clin Endocrinol Metab 2003;88:1516-22
15. Schilling C, Gallicchio L, Miller SR, et al. Current alcohol use is associated with a reduced risk of hot flashes in midlife women. Alcohol Alcohol 2005;40:563-8
16. Gallicchio L, Miller SR, Visvanathan K, et al. Cigarette smoking, estrogen levels, and hot flashes in midlife women. Maturitas 2005;53:133-43
17. Hedley AA, Ogden CL, Johnson CL, Carroll MD, Curtin LR, Flegal KM. Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002. JAMA 2004;291:2847-50
18. Flegal KM, Carroll MD, Ogden CL, Johnson CL. Prevalence and trends in obesity among US adults, 1999-2000. JAMA 2002;288:1723-7
19. Erlik Y, Meldrum DR, Judd HL. Estrogen levels in postmenopausal women with hot flashes. Obstet Gynecol 1982;59:403-7
20. Overlie I, Moen MH, Holte A, Finset A. Androgens and estrogens in relation to hot flashes during the menopausal transition. Maturitas 2002;41:69-77
21. Klinga K, von Holst T, Runnebaum B. Influence of severe obesity on peripheral hormone concentrations in pre- and postmenopausal women. Eur J Obstet Gynecol Reprod Biol 1983;15:102-12
22. Santoro N, Torrens J, Crawford S, et al. Correlates of circulating androgens in mid-life women: the Study of Women Across the Nation. J Clin Endocrinol Metab 2005;90:4836-45
23. Sutton-Tyrrell K, Wildman RP, Matthews KA, et al. Sex hormone-binding globulin and the free androgen index are related to cardiovascular risk factors in multiethnic premenopausal and perimenopausal women enrolled in the Study of Women across the Nation (SWAN). Circulation 2005;111:1242-9
24. Vermeulen A, Verdonck L, Kaufman JM. A critical evaluation of simple methods for the estimation of free testosterone in serum. J Clin Endocrinol Metab 1999;84:3666-72
25. Rinaldi S, Geay A, Dechaud H, et al. Validity of free testosterone and free estradiol determinations in serum samples from postmenopausal women by theoretical calculations. Cancer Epidemiol Biomarkers Prev 2002;11:1065-71
26. Randolph JF Jr, Sowers MF, Bondarenko I, et al. The relationship of longitudinal change in reproductive hormones and vasomotor symptoms during the menopausal transition. J Clin Endocrinol Metab 2005;90:6106-12
27. Vankrieken L. Testosterone and the free androgen index. Diagnostic Products Corporaton, 1997
28. Cunningham SK, Loughlin T, Culliton M, McKenna TJ. The relationship between sex steroids and sex-hormone-binding globulin in plasma in physiological and pathological conditions. Ann Clin Biochem 1985;22:489-97
29. Cunningham GR, Tindall DJ, Lobl TJ, Campbell JA, Means AR. Steroid structural requirements for high affinity binding to human sex steroid binding protein (SBP). Steroids 1981;38:243-62
30. Lukanova A, Lundin E, Zeleniuch-Jacquotte A, et al. Body mass index, circulating levels of sex-steroid hormones, IGF-I and IGF-binding protein-3: a cross-sectional study in healthy women. Eur J Endocrinol 2004;150:161-71
31. Cauley JA, Gutai JP, Kuller LH, LeDonne D, Powell JG. The epidemiology of serum sex hormones in postmenopausal women. Am J Epidemiol 1989;129:1120-31
32. Gavaler JS, VanThiel DH. The association between moderate alcoholic beverage consumption and serum estradiol and testosterone levels in normal postmenopausal women: relationship to the literature. Alcohol Clin Exp Res 1992;16:87-92
33. Sowers MF, La Pietra MT. Menopause: its epidemiology and potential association with chronic diseases. Epidemiol Rev 1995;17:287-302
34. Yoo KY, Kim H, Shin HR, et al. Female sex hormones and body mass in adolescent and postmenopausal Korean women. J Korean Med Sci 1998;13:241-6
35. Lee CC, Kasa-Vubu JZ, Supiano MA. Androgenicity and obesity are independently associated with insulin sensitivity in postmenopausal women. Metabolism 2004;53:507-12
36. Preziosi P, Barrett-Connor E, Papoz L, et al. Interrelation between plasma sex hormone-binding globulin and plasma insulin in healthy adult women: the Telecom Study. J Clin Endocrinol Metab 1993;76:283-7
37. Wu F, Ames R, Evans MC, France JT, Reid IR. Determinants of sex hormone-binding globulin in normal postmenopausal women. Clin Endocrinol 2001;54:81-7
38. Lasley BL, Santoro N, Randolf JF, et al. The relationship of circulating dehydroepiandrosterone, testosterone, and estradiol to stages of the menopausal transition and ethnicity. J Clin Endocrinol Metab 2002;87:3760-7
39. Acs N, Vajo Z, Demendi C, Nadasy G, Monos E, Szekacs B. Estrogen improves impaired musculocutaneous vascular adrenergic reactivity in pharmacologically ovariectomized rats: a potential peripheral mechanism for hot flashes? Gynecol Endocrinol 2001;15:68-73
40. Freedman RR. Biochemical, metabolic, and vascular mechanisms in menopausal hot flashes. Fertil Steril 1998;70:332-7
41. Freedman RR. Physiology of hot flashes. Am J Hum Biol 2001;13:453-64
42. Berendsen HH. The role of serotonin in hot flushes. Maturitas 2000;36:155-64