Synthesis and anticancer activity of a novel class of flavonoids: 2,4-Diarylchromane[4,3-d]-Δ1,9b-1,2,3-thiadiazolines

European Journal of Medicinal Chemistry

Volumn 42, Issue 2, 2007, Pages 226-234

  Ying, Huazhou ^a   Hu, Yongzhou ^a   He, Qiaojun ^a   Li, Runping ^a   Yang, Bo ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

2,4 Diarylchromane 4,3 d 1,9b 1,2,3 thiadiazolines; Antitumor activity; Synthesis

Indexed keywords

1,2,3 THIADIAZOLINE DERIVATIVE; 2 [2 CHLORO 4 (METHYLSULFONYL)PHENYL] 4 (4 CHLOROPHENYL) 3A,4 DIETHOXYLCHROMANE[4,3 D] DELTA 1,9B (1,2,3 THIADIAZOLINE); ANTINEOPLASTIC AGENT; CHROMAN DERIVATIVE; DNA FRAGMENT; FLAVONOID; THIADIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; CYCLIZATION; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHROMANS; CRYSTALLOGRAPHY, X-RAY; DNA FRAGMENTATION; DRUG SCREENING ASSAYS, ANTITUMOR; FLAVONOIDS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, INFRARED; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; THIADIAZOLES;

EID: 33847103870     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2006.10.004     Document Type: Article

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