Psychopathological characteristics and treatment response of first episode compared with multiple episode schizophrenic disorders

European Archives of Psychiatry and Clinical Neuroscience

Volumn 257, Issue 1, 2007, Pages 47-53

  Jäger, Markus ^a   Riedel, Michael ^a   Messer, Thomas ^b   Laux, Gerd ^c   Pfeiffer, Herbert ^d   Naber, Dieter ^e   Schmidt, Lutz G ^f   Gaebel, Wolfgang ^g   Huff, Wolfgang ^h   Heuser, Isabella ⁱ   Kühn, Kai Uwe ^j   Lemke, Matthias R ^k   Rüther, Eckart ^l   Buchkremer, Gerhard ^m   Gastpar, Markus ⁿ   Bottlender, Ronald ^a   Strauß, Anton ^a   Möller, Hans Jürgen ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b District Hospital Augsburg   (Germany)

^c District Hospital Gabersee   (Germany)

^d KLINIKUM MÜNCHEN OST   (Germany)

^e UNIVERSITY OF HAMBURG   (Germany)

^f JOHANNES GUTENBERG UNIVERSITY   (Germany)

^g HEINRICH HEINE UNIVERSITY   (Germany)

^h UNIVERSITY OF COLOGNE   (Germany)

ⁱ CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^j UNIVERSITY OF BONN   (Germany)

^k Rheinische Kliniken   (Germany)

^l UNIVERSITY OF GÖTTINGEN   (Germany)

^m UNIVERSITY OF TÜBINGEN   (Germany)

ⁿ UNIVERSITY OF DUISBURG ESSEN   (Germany)

more..

Author keywords

First episode; Multiple episode; PANSS; Schizophrenic disorders; Treatment response

Indexed keywords

ANTIDEPRESSANT AGENT; ATYPICAL ANTIPSYCHOTIC AGENT; MOOD STABILIZER; NEUROLEPTIC AGENT; TRANQUILIZER;

ADULT; ANALYSIS OF COVARIANCE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; FAMILY THERAPY; FEMALE; FOLLOW UP; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HOSPITAL PATIENT; HUMAN; HYPOTHESIS; INTERNATIONAL CLASSIFICATION OF DISEASES; MAJOR CLINICAL STUDY; MALE; MENTAL PATIENT; NEGATIVE SYNDROME; POSITIVE AND NEGATIVE SYNDROME SCALE; POSITIVE SYNDROME; PRIORITY JOURNAL; PSYCHOEDUCATION; PSYCHOSOCIAL CARE; SCHIZOPHRENIA; SOCIAL ADAPTATION; TREATMENT OUTCOME;

ADULT; ANTIPSYCHOTIC AGENTS; FEMALE; HOSPITALIZATION; HUMANS; LENGTH OF STAY; MALE; PSYCHIATRIC STATUS RATING SCALES; PSYCHOPATHOLOGY; RECURRENCE; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; SOCIAL BEHAVIOR; TREATMENT OUTCOME;

EID: 33847101862     PISSN: 09401334     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00406-006-0683-1     Document Type: Article

References (30)

1. Addington J, Addington D (2002) Cognitive functioning in first-episode schizophrenia. J Psychiatry Neurosci 27:188-192
2. Albus M, Hunmann W, Ehrenberg CH, Forcht U, Mohr U, Sobizack N, Wahlheim CH, Hecht S (1996) Neuropsychological impairment in first-episode and chronic schizophrenic patients. Eur Arch Psychiatry Clin Neurosci 146:249-255
3. American Psychiatric Association (1994) Diagnostic and statistical manual of mental disorders, 4th edn. (DSM-IV). American Psychiatric Association, Washington DC
4. American Psychiatric Association (2004) Practice guideline for the treatment of patients with schizophrenia, 4th edn. American Psychiatric Association, Washington DC
5. Bottlender R, Jäger M, Groll C, Strauss A, Möller HJ (2001) Deficit states in schizophrenia and their association with the length of illness and gender. Eur Arch Psychiatry Clin Neurosci 251:272-278
6. Bottlender R, Sato T, Jäger M, Wegener U, Wittmann J, Strauß A, Möller HJ (2003) The impact of untreated psychosis prior to first psychiatric admission on the 15-year outcome in schizophrenia. Schizophr Res 62:37-44
7. Cuesta MJ, Peralta V, Zarzuela A (1998) Illness duration and neuropsychological impairments in schizophrenia. Schizophr Res 33:141-150
8. Eaton WW, Mortensen PB, Herrman H, Freeman H, Bilker W (1992) Long term course of hospitalization for schizophrenia: part I. Risk for rehospitalisation. Schizophr Bull 18:217-228
9. Falkai P, Wobrock T, Lieberman J, Glenthoj B, Gattez WF, Möller HJ, WFSBP Task Force on Treatment Guidelines for Schizophrenia (2005) World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of schizophrenia, part 1: acute treatment of schizophrenia. World J Biol Psychiatry 6:132-91
10. Gaebel W, Jänner M, Frommamm (2002) First vs multiple episode schizophrenia: two year outcome of intermittent and maintenance medication strategies. Schizophr Res 53:145-159
11. Grant C, Addington J, Addington D, Konnert C (2001) Social functioning in first and multiepisode schizophrenia. Can J Psychiatry 46:746-749
12. Hamilton M (1960) A rating scale for depression. J Neurol Neurosurg Psychiatry 23:56-62
13. Kay SR (1991) Positive and negative syndromes in schizophrenia: assessment and research. Clinical and experimental psychiatry monography No. 5 Brunner/Mazel, New York
14. Kraepelin E (1899) Psychiatrie, 6th edn. Barth, Leipzig
15. Larsen TK, Friis S, Haahr U, Joa I, Johannessen JO, Melle I, Opjordsmoen S, Simonsen E, Vaglum P (2001) Early detection and intervention in first episode schizophrenia: a critical review. Acta Psychiatr Scand 103:323-334
16. Lieberman JA, Alvir J, Woerner M, Degreet G, Bilder RM, Ashtari M, Bogerts B, Mayerhoff DI, Geisler SH, Loebel A, Levy DL, Hinrichsen G, Szymanski S, Chakos M, Koreen A, Borenstein M, Kane J (1992) Prospective study of psychobiology in first episode schizophrenia at Hillside Hospital. Schizophr Bull 18:351-371
17. Lieberman JA, Koreen AR, Chakos M, Sheitman B, Woerner M, Alvir J, Bilder R (1996) Factors influencing treatment response and outcome of first episode schizophrenia: implications for Understanding the pathophysiology of schizophrenia. J Clin Psychiatry 57(suppl9):5-9
18. Lieberman JA (1999) Is schizophrenia a neurodegenerative disorder? A clinical and neurobiological perspective. Biol Psychiatry 46:729-739
19. Meltzer HY, Rabinowitz J, Lee MA (1997) Age at onset and gender in schizophrenic patients in relation to neuroleptic resistance. Am J Psychiatry 154:475-482
20. Moritz S, Lambert M, Andresen B, Bothern A, Naber D, Krausz M (2001) Subjective cognitive dysfunction in first-episode and chronic schizophrenic patients. Compr Psychiatry 42:213-216
21. Moritz S, Andresen B, Perro C, Schickel M, Kraus M, Naber D, PERSIST Study Group (2002) Neurocognitive performance in first episode and chronic schizophrenic patients. Eur Arch Psychiatry Clin Neurosci 252:33-37
22. Murphy BM, Burke JG, Bray JC, Walsh D, Kendler KS (1994) An analysis of the clinical features of familial schizophrenia. Acta Psychiatr Scand 89:421-427
23. National Institute for Clinical Excellence (2002) Schizophrenia. Core interventions in the treatment and management of schizophrenia in primary and secondary care. NICE, London
24. Ohlsen RI, O'Toole MS, Purvis RG, Walters JTR, Taylor TM, Jones HM, Pilowsky LS (2004) Clinical effectiveness in first episode patients. European Neuropsychopharamacology 14:S445-S451
25. Oosthuizen P, Emsley RA, Keyter K, Niehaus DJH, Koen L (2005) Duration of untreated psychosis and outcome in first episode psychosis. Perspective from a developing country. Acta Psychiatr Scand 11:214-219
26. Sanger TM, Lieberman JA, Tohen M, Grundy A, Beasly C, Tollefson GD (1999) Olanzapine versus haloperidol treatment in first-episode psychosis. Am J Psychiatry 165:79-87
27. Shtasel DL, Gur RE, Gallacher F, Heimberg C, Cannon T, Gur RC (1992) Phenomenology and functioning in first-episode schizophrenia. Schizophr Bull 18:449-462
28. Strauss JS, Carpenter WT Jr (1974) The prediction of outcome in schizophrenia. II. Relationsships between predictor and outcome variables: a report from the WHO International Pilot Study of Schizophrenia. Ach Gen Psychiatry 31:37-42
29. WHO (1993) The ICD-10 classification of mental and behavioural disorders. Diagnostic criteria for research. WHO, Geneva
30. Wölwer W, Buchkremer G, Häfner H, Klosterkötter J, Maier W, Möller HJ, Gaebel W (2003) German research network on schizophrenia. Bridging the gap between research and care. Eur Arch Clin Neurosci 253:321-329