Editorial commentary on fixed combination isosorbide dinitrate/hydralazine for nitric-oxide-enhancing therapy in heart failure

Expert Opinion on Pharmacotherapy

Volumn 8, Issue 3, 2007, Pages 275-277

  Flack, John M ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

AHEFT; Isosorbide dinitrate hydralazine; Systolic heart failure

Indexed keywords

DIGITALIS; DIURETIC AGENT; ENALAPRIL; HYDRALAZINE PLUS ISOSORBIDE DINITRATE; LOSARTAN; PLACEBO; PRAZOSIN;

AFRICAN AMERICAN; ASIAN; CAUCASIAN; CLINICAL TRIAL; DRUG APPROVAL; DRUG EFFICACY; DRUG RESPONSE; EDITORIAL; ETHNICITY; FOLLOW UP; FOOD AND DRUG ADMINISTRATION; HEART FAILURE; HEART LEFT VENTRICLE FAILURE; HISPANIC; HUMAN; HYPERTENSION; MORTALITY; RACE DIFFERENCE; RISK REDUCTION; STATISTICAL SIGNIFICANCE; SYSTOLIC HEART FAILURE;

AFRICAN AMERICANS; CHEMISTRY, PHARMACEUTICAL; DRUG COMBINATIONS; HEART FAILURE, CONGESTIVE; HUMANS; HYDRALAZINE; ISOSORBIDE DINITRATE; NITRIC OXIDE DONORS;

EID: 33847056152     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.8.3.275     Document Type: Editorial

References (8)

1. TAYLOR AL, ZIESCHE S, YANCY C, CARSON P et al. FOR THE AFRICAN AMERICAN HEART FAILURE TRIAL INVESTIGATORS: Combination of isosorbide dinitrate and hydralazine in blacks with heart failure. N. Engl. J. Med. (2004) 351:2049-2057.
2. FRANCIOSA JA: Fixed combination isosorbide dinitrate/hydralazine for nitric-oxide-enhancing therapy in heart failure. Expert Opin. Pharmacother. (2006) 7(18):2521-2531.
3. COHN JN, ARCHIBALD DG, ZIESCHE S, FRANCIOSA JA et al.: Effect of vasodilator therapy on mortality in chronic congestive heart failure. N. Engl. J. Med. (1986) 314:1547-1542.
4. COHN JN, JOHNSON G, ZIESCHE S, COBB F et al.: A comparison of enalapril with isosorbide dinitrate/hydralazine in the treatment of chronic congestive heart failure. N. Engl. J. Med. (1991) 325:303-310.
5. CARSON P, ZIESCHE S, JOHNSON G, COHN JN FOR THE VASODILATOR-HEART TRIAL STUDY GROUP: Racial differences in response to therapy for heart failure: analysis of vasodilator-heart failure trials. J. Card Fail. (1999) 5(3):178-187.
6. PACKER M, O'CONNOR CM, GHALI JE, PRESSLER ML et al.: Effect of amlodipine on morbidity and mortality in severe chronic heart failure. Prospective randomized amlodipine survival evaluation study group. N. Engl. J. Med. (1996) 355(15):1107-1114.
7. EXNER DV, DRIES DL, DOMANSKI MJ, COHN JN: Lesser response to angiotensin-converting-enzyme inhibitor therapy in black as compared with white patients with left ventricular dysfunction. N. Engl. J. Med. (2001) 344(18):1351-1357.
8. DRIES DL, STRONG MH, COOPER RS, DRAZNER MH: Efficacy of angiotensin-converting enzyme inhibition in reducing progression from asymptomatic left ventricular dysfunction to symptomatic heart failure in black and white patients. J. Am. Coll. Cardiol. (2002) 40:311-317.