Computed tomography and cystic fibrosis: Promises and problems

Thorax

Volumn 62, Issue 2, 2007, Pages 181-186

  Aziz, Z A ^a   Davies, J C ^b   Alton, E W ^b   Wells, A U ^a   Geddes, D M ^a   Hansell, D M ^a  

^a ROYAL BROMPTON HOSPITAL   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CLINICAL ASSESSMENT; CLINICAL RESEARCH; COMPUTER ASSISTED TOMOGRAPHY; CYSTIC FIBROSIS; DIAGNOSTIC TEST; EVIDENCE BASED MEDICINE; HUMAN; LUNG FUNCTION TEST; LUNG INJURY; LUNG STRUCTURE; LUNG VOLUME; OUTCOME ASSESSMENT; PATIENT MONITORING; PRIORITY JOURNAL; RADIATION DOSE; REPRODUCIBILITY; REVIEW; RISK FACTOR; SENSITIVITY ANALYSIS;

CLINICAL TRIALS; CYSTIC FIBROSIS; FORCED EXPIRATORY VOLUME; HUMANS; RADIATION DOSAGE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME;

EID: 33847053661     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.2005.054379     Document Type: Review

References (53)

1. Hansell DM, Strickland B. High-resolution computed tomography in pulmonary cystic fibrosis. Br J Radiol 1989;62:1-5.
2. Santis G, Hodson ME, Strickland B. High resolution computed tomography in adult cystic fibrosis patients with mild lung disease. Clin Radiol 1991;44:20-2.
3. Jacobsen LE, Houston CS, Habbick BF, et al. Cystic fibrosis: a comparison of computed tomography and plain chest radiographs. J Can Assoc Radiol 1986;37:17-21.
4. Bhalla M, Turcios N, Aponte V, et al. Cystic fibrosis: scoring system with thin-section CT. Radiology 1991;179:783-8.
5. Brody AS, Molina PL, Klein JS, et al. High-resolution computed tomography of the chest in children with cystic fibrosis: support for use as an outcome surrogate. Pediatr Radiol 1999;29:731-5.
6. Helbich TH, Heinz-Peer G, Eichler I, et al. Cystic fibrosis: CT assessment of lung involvement in children and adults. Radiology 1999;213:537-44.
7. Santamaria F, Grillo G, Guidi G, et al. Cystic fibrosis: when should high-resolution computed tomography of the chest be obtained? Pediatrics 1998;101:908-13.
8. de Jong PA, Ottink MD, Robben SG, et al. Pulmonary disease assessment in cystic fibrosis: comparison of CT scoring systems and value of bronchial and arterial dimension measurements. Radiology 2004;231:434-9.
9. Brody AS, Klein JS, Molina PL, et al. High-resolution computed tomography in young patients with cystic fibrosis: distribution of abnormalities and correlation with pulmonary function tests. J Pediatr 2004;145:32-8.
10. Brody AS, Sucharew H, Campbell JD, et al. Computed tomography correlates with pulmonary exacerbations in children with cystic fibrosis. Am J Respir Crit Care Med 2005;172:1128-32.
11. Brody AS, Kosorok MR, Li Z, et al. Reproducibility of a scoring system for computed tomography scanning in cystic fibrosis. J Thorac Imaging 2006;21:14-21.
12. de Jong PA, Nakano Y, Hop WC, et al. Changes in airway dimensions on computed tomography scans of children with cystic fibrosis. Am J Respir Crit Care Med 2005;172:218-24.
13. Venkatraman R, Raman R, Raman B, et al. Fully automated system for three-dimensional bronchial morphology analysis using volumetric multidetector computed tomography of the chest. J Digit Imaging 2006;19:132-9.
14. Goris ML, Zhu HJ, Blankenberg F, et al. An automated approach to quantitative air trapping measurements in mild cystic fibrosis. Chest 2003;123:1655-63.
15. Bonnel AS, Song SM, Kesavarju K, et al. Quantitative air-trapping analysis in children with mild cystic fibrosis lung disease. Pediatr Pulmonol 2004;38:396-405.
16. Robinson TE, Goris ML, Zhu HJ, et al. Dornase alfa reduces air trapping in children with mild cystic fibrosis lung disease. A quantitative analysis. Chest 2005;128:2327-35.
17. Roberts HR, Wells AU, Milne DG, et al. Airflow obstruction in bronchiectasis: correlation between computed tomography features and pulmonary function tests. Thorax 2000;55:198-204.
18. Sheehan RE, Wells AU, Copley SJ, et al. A comparison of serial computed tomography and functional change in bronchiectasis. Eur Respir J 2002;20:581-7.
19. Ooi GC, Khong PL, Chan-Yeung M, et al. High-resolution CT quantification of bronchiectasis: clinical and functional correlation. Radiology 2002;225:663-72.
20. de Jong PA, Lindblad A, Rubin L, et al. Progression of lung disease on computed tomography and pulmonary function tests in children and adults with cystic fibrosis. Thorax 2006;61:80-5.
21. Martinez TM, Llapur CJ, Williams TH, et al. High-resolution computed tomography imaging of airway disease in infants with cystic fibrosis. Am J Respir Crit Care Med 2005;172:1133-8.
22. Long FR, Williams RS, Castile RG. Structural airway abnormalities in infants and young children with cystic fibrosis. J Pediatr 2004;144:154-61.
23. Coblentz CL, Babcook G, Alton D, et al. Observer variation in detecting the radiologic features associated with bronchiolitis. Invest Radiol 1991;26:115-8.
24. Oppo K, Leen E, Angerson WJ, et al. Doppler perfusion index: an interobserver and intraobserver reproducibility study. Radiology 1998;208:453-7.
25. Muller NL, Staples CA, Miller RR, et al. "Density mask". An objective method to quantitate emphysema using computed tomography. Chest 1988;94:782-7.
26. Kinsella M, Muller NL, Abboud RT, et al. Quantitation of emphysema by computed tomography using a "density mask" program and correlation with pulmonary function tests. Chest 1990;97:315-21.
27. Knudson RJ, Standen JR, Kaltenborn WT, et al. Expiratory computed tomography for assessment of suspected pulmonary emphysema. Chest 1991;99:1357-60.
28. Long FR. High-resolution CT of the lungs in infants and young children. J Thorac Imaging 2001;16:251-8.
29. Bankier AA, Van Muylem A, Scillia P, et al. Air trapping in heart-lung transplant recipients: variability of anatomic distribution and extent at sequential expiratory thin-section CT. Radiology 2003;229:737-42.
30. Kauczor HU, Heussel CP, Fischer B, et al. Value of spirometry-gated high resolution computerized tomography of the lung during inspiration and expiration. Rofo 1998;169:658-61.
31. de Jong PA, Nakano Y, Lequin MH, et al. Dose reduction for CT in children with cystic fibrosis: is it feasible to reduce the number of images per scan? Pediatr Radiol 2005;25:1-4.
32. de Jong PA, Nakano Y, Lequin MH, et al. Progressive damage on high resolution computed tomography despite stable lung function in cystictibrosis. Eur Respir J 2004;23:93-7.
33. de Jong PA, Mayo JR, Golmohammadi K, et al. Estimation of cancer mortality associated with repetitive computed tomography scanning. Am J Respir Crit Care Med 2006;173:199-203.
34. Siegel MJ. Multiplanar and three-dimensional multi-detector row CT of thoracic vessels and airways in the pediatric population. Radiology 2003;229:641-50.
35. Lucaya J, Piqueras J, Garcia-Pena P, et al. Low-dose high-resolution CT of the chest in children and young adults: dose, cooperation, artifact incidence, and image quality. AJR Am J Roentgenol 2000;175:985-92.
36. Cody DD, Moxley DM, Krugh ICT, et al. Strategies for formulating appropriate MDCT techniques when imaging the chest, abdomen, and pelvis in pediatric patients. AJR Am J Roentgenol 2004;182:849-59.
37. Lee EY, Siegel MJ, Hildebolt CF, et al. MDCT evaluation of thoracic aortic anomalies in pediatric patients and young adults: comparison of axial, multiplanar, and 3D images. AJR Am J Roentgenol 2004;182:777-84.
38. Schalzlcin A, Gail M. The promise and peril or surrogate end points in cancer research. Nat Rev Cancer 2002;2:19-27.
39. Prentice RL. Surrogate endpoints in clinical trials: definition and operational criteria. Stat Med 1989;8:431-40.
40. Fleming TR, DeMets DL. Surrogate end points in clinical trials: are we being misled? Ann Intern Med 1996;125:605-13.
41. Temple RJ. A regulator authority's opinion about surrogate endpoints. In: Clinical measurements on drug evaluation. New York: Wiley, 1995.
42. Helbich TH, Heinz-Peer G, Fleischmann D, et al. Evolution of CT findings in patients with cystic fibrosis. AJR Am J Roentgenol 1999;173:81-8.
43. Brody AS. Early morphologic changes in the lungs of asymptomatic infants and young children with cystic fibrosis. J Pediatr 2004;144:154-61.
44. Larsson A, Jonmarker C, Werner O. Ventilation inhomogeneity during controlled ventilation. Which index should be used? J Appl Physiol 1988;65:2030-9.
45. Aurora P, Bush A, Gustafsson P, et al. Multiple-breath washout as a marker of lung disease in preschool children with cystic fibrosis. Am J Respir Crit Care Med 2005;171:249-56.
46. Kraemer R, Blum A, Schibler A, et al. Ventilation inhomogeneities in relation to standard lung function in patients with cystic fibrosis. Am J Respir Crit Care Med 2005;171:371-8.
47. Robinson TE, Leung AN, Northway WH, et al. Composite spirometric-computed tomography outcome measure in early cystic fibrosis lung disease. Am J Respir Crit Care Med 2003;168:588-93.
48. Nasr SZ, Kuhns LR, Brown RW, et al. Use of computerized tomography and chest x-rays in evaluating efficacy of aerosolized recombinant human DNase in cystic fibrosis patients younger than age 5 years: a preliminary study. Pediatr Pulmonol 2001;31:377-82.
49. Robinson TE, Leung AN, Northway WH, et al. Spirometer-triggered high-resolution computed tomography and pulmonary function measurements during an acute exacerbation in patients with cystic fibrosis. J Pediatr 2001;138:553-9.
50. Shah RM, Sexauer W, Ostrum BJ, et al. High resolution CT in the acute exacerbation of cystic fibrosis: evaluation of acute findings, reversibility of those findings, and clinical correlation. AJR Am J Roentgenol 1997;169:375-80.
51. Brody AS, Molina PL, Klein JS, et al. High-resolution computed tomography of the chest in children with cystic fibrosis: support for use as an outcome surrogate. Pediatr Radiol 1999;29:731-5.
52. Koumellis P, van Beek EJ, Woodhouse N, et al. Quantitative analysis of regional airways obstruction using dynamic hyperpolarized 3He MRI-preliminary results in children with cystic fibrosis. J Magn Reson Imaging 2005;22:420-6.
53. Mentore K, Froh DK, de Lange EE, et al. Hyperpolarized HHe 3 MRI of the lung in cystic fibrosis: assessment at baseline and after bronchodilator and airway clearance treatment. Acad Radiol 2005;12:1423-9.