Developmental divergence of sleep-wake patterns in orexin knockout and wild-type mice

European Journal of Neuroscience

Volumn 25, Issue 2, 2007, Pages 512-518

  Blumberg, Mark S ^a   Coleman, Cassandra M ^a   Johnson, Eric D ^a   Shaw, Cynthia ^a  

^a E11 SSH   (United States)

Author keywords

Atonia; Development; Hypocretin; Knockout; Mouse; Orexin

Indexed keywords

OREXIN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; FEMALE; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; SLEEP WAKING CYCLE; STATISTICAL SIGNIFICANCE; WILD TYPE;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; CIRCADIAN RHYTHM; ELECTROENCEPHALOGRAPHY; FEMALE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, KNOCKOUT; NEUROPEPTIDES; SLEEP; WAKEFULNESS;

EID: 33847045635     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2006.05292.x     Document Type: Article

References (38)

1. Abbey, H. & Howard, E. (1973) Statistical procedure in developmental studies on species with multiple offspring. Dev. Psychobiol., 6, 329-335.
2. Aston-Jones, G., Chen, S., Zhu, Y. & Oshinsky, M.L. (2001) A neural circuit for circadian regulation of arousal. Nature Neurosci., 4, 732-738.
3. Blumberg, M.S., Karlsson, K.Æ., Seelke, A.M.H. & Mohns, E.J. (2005a) The ontogeny of mammalian sleep: a response to Frank and Heller (2003). J. Sleep Res., 14, 91-101.
4. Blumberg, M.S., Seelke, A.M., Lowen, S.B. & Karlsson, K.A. (2005b) Dynamics of sleep-wake cyclicity in developing rats. Proc. Natl Acad. Sci. USA, 102, 14860-14864.
5. Chemelli, R.M.,Willie, J.T., Sinton, C.M., Elmquist, J.K., Scammell, T., Lee, C., Richardson, J.A., Williams, S.C., Xiong, Y., Kisanuki, Y., Fitch, T.E., Nakazato, M., Hammer, R.E., Saper, C.B. & Yanagisawa, M. (1999) Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell, 98, 437-451.
6. Chou, T.C., Scammell, T.E., Gooley, J.J., Gaus, S.E., Saper, C.B. & Lu, J. (2003) Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms. J. Neurosci., 23, 10691-10702.
7. Dijk, D.J. & Czeisler, C.A. (1995) Contribution of the circadian pacemaker and the sleep homeostat to sleep propensity, sleep structure, electroencephalographic slow waves, and sleep spindle activity in humans. J. Neurosci., 15, 3526-3538.
8. Frank, M.G. & Heller, H.C. (1997) Development of diurnal organization of EEG slow-wave activity and slow-wave sleep in the rat. Am. J. Physiol., 273, R472-R478.
9. Gerashchenko, D., Kohls, M.D., Greco, M., Waleh, N.S., Salin-Pascual, R., Kilduff, T.S., Lappi, D.A. & Shiromani, P.J. (2001) Hypocretin-2-saporin lesions of the lateral hypothalamus produce narcoleptic-like sleep behavior in the rat. J. Neurosci., 21, 7273-7283.
10. Gramsbergen, A., Schwartze, P. & Prechtl, H.F.R. (1970) The postnatal development of behavioral states in the rat. Dev. Psychobiol., 3, 267-280.
11. Holson, R.R. & Pearce, B. (1992) Principles and pitfalls in the analysis of prenatal treatment effects in multiparous species. Neurotoxicol. Teratol., 14, 221-228.
12. Jenni, O.G., Deboer, T. & Achermann, P. (2006) Development of the 24-h rest-activity pattern in human infants. Infant Behav. Dev., 29, 143-152.
13. John, J., Wu, M.F., Maidment, N.T., Lam, H.A., Boehmer, L.N., Patton, M. & Siegel, J.M. (2004) Developmental changes in CSF hypocretin-1 (orexin-A) levels in normal and genetically narcoleptic Doberman pinschers. J. Physiol., 560, 587-592.
14. Karlsson, K.Æ. & Blumberg, M.S. (2005) Active medullary control of atonia in week-old rats. Neuroscience, 130, 275-283.
15. Karlsson, K.Æ., Gall, A.J., Mohns, E.J., Seelke, A.M.H. & Blumberg, M.S. (2005) The neural substrates of infant sleep in rats. Plos. Biol., 3, 891-901.
16. Karlsson, K.Æ., Kreider, J.C. & Blumberg, M.S. (2004) Hypothalamic contribution to sleep-wake cycle development. Neuroscience, 123, 575-582.
17. de Lecea, L., Kilduff, T.S., Peyron, C., Gao, X., Foye, P.E., Danielson, P.E., Fukuhara, C., Battenberg, E.L., Gautvik, V.T., Bartlett, F.S., 2nd, Frankel, W.N., van den Pol, A.N., Bloom, F.E., Gautvik, K.M. & Sutcliffe, J.G. (1998) The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc. Natl Acad. Sci. USA, 95, 322-327.
18. Kleitman, N. & Engelmann, T.G. (1953) Sleep characteristics of infants. J. Appl. Physiol., 6, 269-282.
19. Lin, L., Faraco, J., Li, R., Kadotani, H., Rogers, W., Lin, X., Qiu, X., de Jong, P.J., Nishino, S. & Mignot, E. (1999) The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene. Cell, 98, 365-376.
20. Lo, C.C., Amaral, L.A.N., Havlin, S., Ivanov, P.C., Penzel, T., Peter, J.H. & Stanley, H.E. (2002) Dynamics of sleep-wake transitions during sleep. Europhysics Lett., 57, 625-631.
21. Lo, C.C., Chou, T., Penzel, T., Scammell, T.E., Strecker, R.E., Stanley, H.E. & Ivanov, P.C. (2004) Common scale-invariant patterns of sleep-wake transitions across mammalian species. Proc. Natl. Acad. Sci. USA, 101, 17545-17548.
22. Mochizuki, T., Crocker, A., McCormack, S., Yanagisawa, M., Sakurai, T. & Scammell, T.E. (2004) Behavioral state instability in orexin knock-out mice. J. Neurosci., 24, 6291-6300.
23. Mohns, E.J., Karlsson, K.Æ. & Blumberg, M.S. (2006) The preoptic hypothalamus and basal forebrain play opposing roles in the descending modulation of sleep sleep and wakefulness in infant rats. Eur. J. Neurosci., 23, 1301-1310.
24. Peyron, C., Faraco, J., Rogers, W., Ripley, B., Overeem, S., Charnay, Y., Nevsimalova, S., Aldrich, M., Reynolds, D., Albin, R., Li, R., Hungs, M., Pedrazzoli, M., Padigaru, M., Kucherlapati, M., Fan, J., Maki, R., Lammers, G.J., Bouras, C., Kucherlapati, R., Nishino, S. & Mignot, E. (2000) A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nature Med., 6, 991-997.
25. Peyron, C., Tighe, D.K., van den Pol, A.N., de Lecea, L., Heller, H.C., Sutcliffe, J.G. & Kilduff, T.S. (1998) Neurons containing hypocretin (orexin) project to multiple neuronal systems. J. Neurosci., 18, 9996-10015.
26. van den Pol, A.N. (2000) Narcolepsy: a neurodegenerative disease of the hypocretin system? Neuron, 27, 415-418.
27. van den Pol, A.N., Ghosh, P.K., Liu, R.J., Li, Y., Aghajanian, G.K. & Gao, X.B. (2002) Hypocretin (orexin) enhances neuron activity and cell synchrony in developing mouse GFP-expressing locus coeruleus. J. Physiol., 541, 169-185.
28. van den Pol, A.N., Patrylo, P.R., Ghosh, P.K. & Gao, X.B. (2001) Lateral hypothalamus: Early developmental expression and response to hypocretin (orexin). J. Comp. Neurol., 433, 349-363.
29. Riehl, J., Nishino, S., Cederberg, R., Dement, W.C. & Mignot, E. (1998) Development of cataplexy in genetically narcoleptic Dobermans. Exp. Neurol., 152, 292-302.
30. Sakurai, T., Amemiya, A., Ishii, M., Matsuzaki, I., Chemelli, R.M., Tanaka, H., Williams, S.C., Richarson, J.A., Kozlowski, G.P., Wilson, S., Arch., J.R., Buckingham, R.E., Haynes, A.C., Carr, S.A., Annan, R.S., McNulty, D.E., Liu, W.S., Terrett, J.A., Elshourbagy, N.A., Bergsma, D.J. & Yanagisawa, M. (1998) Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell, 92, 573-585.
31. Saper, C.B., Chou, T.C. & Scammell, T.E. (2001) The sleep switch: hypothalamic control of sleep and wakefulness. TINS, 24, 726-731.
32. Saper, C.B., Scammell, T.E. & Lu, J. (2005) Hypothalamic regulation of sleep and circadian rhythms. Nature, 437, 1257-1263.
33. Seelke, A.M.H., Karlsson, K.Æ., Gall, A.J. & Blumberg, M.S. (2005) Extraocular muscle activity, rapid eye movements, and the development of active and quiet sleep. Eur. J. Neurosci., 22, 911-920.
34. Siegel, J.M., Moore, R., Thannickal, R. & Nienhuis, R. (2001) A brief history of hypocretin/orexin and narcolepsy. Neuropsychopharmacology, 25, S14-S20.
35. Taheri, S., Zeitzer, J.M. & Mignot, E. (2002) The role of hypocretins (orexins) in sleep regulation and narcolepsy. Annu. Rev. Neurosci., 25, 283-313.
36. Thannickal, T.C., Moore, R.Y., Nienhuis, R., Ramanathan, L., Gulyani, S., Aldrich, M., Cornford, M. & Siegel, J.M. (2000) Reduced number of hypocretin neurons in human narcolepsy. Neuron, 27, 469-474.
37. Willie, J.T., Chemelli, R.M., Sinton, C.M., Tokita, S., Williams, S.C., Kisanuki, Y.Y., Marcus, J.N., Lee, C., Elmquist, J.K., Kohlmeier, K.A., Leonard, C.S., Richardson, J.A., Hammer, R.E. & Yanagisawa, M. (2003) Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes. Neuron, 38, 715-730.
38. Yamamoto, Y., Ueta, Y., Hara, Y., Serino, R., Nomura, M., Shibuya, I., Shirahata, A. & Yamashita, H. (2000) Postnatal development of orexin/hypocretin in rats. Brain Res. Mol. Brain Res., 78, 108-119.