Effect of aminoguanidine treatment on diabetes-induced changes in the myenteric plexus of rat ileum

Autonomic Neuroscience: Basic and Clinical

Volumn 132, Issue 1-2, 2007, Pages 16-26

  Shotton, Hannah R ^a   Adams, Ashok ^a   Lincoln, Jill ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Aminoguanidine; Autonomic neuropathy; Diabetes mellitus; Myenteric; Nitric oxide synthase

Indexed keywords

AMINOGUANIDINE; DRINKING WATER; NITRIC OXIDE SYNTHASE; NORADRENALIN; STREPTOZOCIN; TYROSINE 3 MONOOXYGENASE; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DIABETIC NEUROPATHY; DISEASE COURSE; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVITY; ILEUM; IMMUNOHISTOCHEMISTRY; INTESTINE INNERVATION; MALE; MYENTERIC PLEXUS; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; TREATMENT OUTCOME; VARICOSIS;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEUROPATHIES; ENZYME INHIBITORS; GUANIDINES; ILEUM; IMMUNOHISTOCHEMISTRY; MALE; MYENTERIC PLEXUS; NERVE DEGENERATION; NEURONS; NITRIC OXIDE SYNTHASE TYPE I; NOREPINEPHRINE; RATS; RATS, WISTAR; VASOACTIVE INTESTINAL PEPTIDE;

EID: 33847040675     PISSN: 15660702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autneu.2006.08.007     Document Type: Article

References (58)

1. Adeghate E., Ponery A.S., Sharma A.K., El-Sharkawy T., and Donáth T. Diabetes mellitus is associated with a decrease in vasoactive intestinal polypeptide content of gastrointestinal tract of rat. Arch. Physiol. Biochem. 109 (2001) 246-251
2. Adeghate E., al-Ramadi B., Saleh A.M., Vijayarasathy C., Ponery A.S., Arafat K., Howarth F.C., and El-Sharkawy T. Increase in neuronal nitric oxide synthase content of the gastroduodenal tract of diabetic rats. Cell. Mol. Life Sci. 60 (2003) 1172-1179
3. Belai A., Lincoln J., Milner P., Crowe R., Loesch A., and Burnstock G. Enteric nerves in diabetic rats: increase in vasoactive intestinal polypeptide but not substance P. Gastroenterology 89 (1985) 967-976
4. Belai A., Lincoln J., and Burnstock G. Lack of release of vasoactive intestinal polypeptide and calcitonin gene-related peptide during electrical stimulation of enteric nerves in streptozotocin-diabetic rats. Gastroenterology 93 (1987) 1034-1040
5. Belai A., Lincoln J., Milner P., and Burnstock G. Progressive changes in adrenergic, serotonergic, and peptidergic nerves in proximal colon of streptozotocin-diabetic rats. Gastroenterology 95 (1988) 1234-1241
6. Belai A., Lincoln J., Milner P., and Burnstock G. Differential effect of streptozotocin-induced diabetes on the innervation of the ileum and distal colon. Gastroenterology 100 (1991) 1024-1032
7. Belai A., Facer P., Polak J.M., and Burnstock G. Effect of streptozotocin-diabetes on the level of VIP mRNA in myenteric neurons. NeuroReport 4 (1993) 291-294
8. Brownlee M. Glycation products and the pathogenesis of diabetic complications. Diabetes Care 15 (1992) 1835-1843
9. Bryk K., Lubeskie A., and Wolff D.J. Studies of neuronal nitric oxide synthase inactivation by diverse suicide inhibitors. Arch. Biochem. Biophys. 369 (1999) 243-251
10. Cameron N.C., and Cotter M.A. Potential therapeutic approaches to the treatment or prevention of diabetic neuropathy: evidence from experimental studies. Diabet. Med. 10 (1993) 593-605
11. Cameron N.E., Cotter M.A., and Robertson S. Essential fatty acid diet supplementation. Effects on peripheral nerve and skeletal muscle function and capillarization in streptozocin-induced diabetic rats. Diabetes 40 (1991) 532-539
12. Cameron N.E., Cotter M.A., Dines K., and Love A. Effects of aminoguanidine on peripheral nerve function and polyol pathway metabolites in streptozotocin-diabetic rats. Diabetologia 35 (1992) 946-950
13. Cellek S., Foxwell N.A., and Moncada S. Two phases of nitrergic neuropathy in streptozotocin induced diabetic rats. Diabetes 52 (2003) 2353-2362
14. Cellek S., Qu W., Schmidt A.M., and Moncada S. Synergistic action of advanced glycation end products and endogenous nitric oxide leads to neuronal apoptosis in vitro: a new insight into selective nitrergic neuropathy in diabetes. Diabetologia 47 (2004) 331-339
15. Costa M., Furness J.B., Pompolo S., Brookes S.J.H., Bornstein J.C., Bredt D.S., and Snyder S.H. Projections and chemical coding of neurons with immunoreactivity for nitric oxide synthase in the guinea-pig small intestine. Neurosci. Lett. 148 (1992) 121-125
16. Courderot-Masuyer C., Dalloz F., Maupoil V., and Rochette L. Antioxidant properties of aminoguanidine. Fundam. Clin. Pharmacol. 13 (1999) 535-540
17. Craner M.J., Klein J.P., Black J.A., and Waxman S.G. Preferential expression of IGF-1 in small DRG neurons and down-regulation following injury. NeuroReport 13 (2002) 1649-1652
18. Dewhurst M., Omawari N., and Tomlinson D.R. Aminoguanidine - effects on endoneurial vasoactive nitric oxide and on motor nerve conduction velocity in control and streptozotocin-diabetic rats. Br. J. Pharmacol. 120 (1997) 593-598
19. Di Giulio A.M., Tenconi B., La Croix R., Mantegazza P., Cattabeni F., and Gorio A. Denervation and hyperinnervation in the nervous system of diabetic animals: I. The autonomic neuronal dystrophy of the gut. J. Neurosci. Res. 24 (1989) 355-361
20. Dyck P.J., Kratz K.M., Karnes J.L., Litchy W.J., Klein R., Pach J.M., Wilson D.M., O'Brien P.C., Melton III L.J., and Service F.J. The prevalence by staged severity of various types of diabetic neuropathy, retinopathy, and nephropathy in a population-based cohort: the Rochester Diabetic Neuropathy Study. Neurology 43 (1993) 817-824
21. Ekblad E., Mulder H., Uddman R., and Sundler F. NOS-containing neurons in the rat gut and coeliac ganglia. Neuropharmacology 33 (1994) 1323-1331
22. Ekblad E., Mulder H., and Sundler F. Vasoactive intestinal peptide expression in enteric neurons is upregulated by both colchicine and axotomy. Regul. Pept. 63 (1996) 113-121
23. Ekblad E., Sjuve R., Arner A., and Sundler F. Enteric neuronal plasticity and a reduced number of interstitial cells of Cajal in hypertrophic rat ileum. Gut 42 (1998) 836-844
24. El-Salhy M., and Spångéus A. Neuropeptide contents of the duodenum of non-obese diabetic mice. Acta Diabetol. 35 (1998) 9-12
25. Giardino I., Fard A.K., Hatchell D.L., and Brownlee M. Aminoguanidine inhibits reactive oxygen species formation, lipid peroxidation, and oxidant-induced apoptosis. Diabetes 47 (1998) 1114-1120
26. Jamal G.A., and Carmichael H. The effect of gamma-linolenic acid on human diabetic peripheral neuropathy: a double-blind placebo-controlled trial. Diabet. Med. 7 (1990) 319-323
27. Jianmongkol S., Vuletich J.L., Bender A.T., Demady D.R., and Osawa Y. Aminoguanidine-mediated inactivation and alteration of neuronal nitric-oxide synthase. J. Biol. Chem. 275 (2000) 13370-13376
28. Kumari K., Umar S., Bansal V., and Sahib M.K. Monoaminoguanidine inhibits aldose reductase. Biochem. Pharmacol. 41 (1991) 1527-1528
29. Li Z.S., and Furness J.B. Inputs from intrinsic primary afferent neurons to nitric oxide synthase-immunoreactive neurons in the myenteric plexus of guinea pig ileum. Cell Tissue Res. 299 (2000) 1-8
30. Lin Z., Gao N., Hu H.Z., Liu S., Gao C., Kim G., Ren J., Xia Y., Peck O.C., and Wood J.D. Immunoreactivity of Hu proteins facilitates identification of myenteric neurons in guinea-pig small intestine. Neurogastroenterol. Motil. 14 (2002) 197-204
31. Lin Z., Sandgren K., and Ekblad E. Increased expression of vasoactive intestinal polypeptide in cultured myenteric neurons from adult rat small intestine. Auton. Neurosci. 107 (2003) 9-19
32. Lincoln J., and Messersmith W.A. Conditions required for the measurement of nitric oxide synthase activity in a myenteric plexus/smooth muscle preparation from the rat ileum. J. Neurosci. Methods 59 (1995) 191-197
33. Lincoln J., Bokor J.T., Crowe R., Griffith S.G., Haven A.J., and Burnstock G. Myenteric plexus in streptozotocin-treated rats. Neurochemical and histochemical evidence for diabetic neuropathy in the gut. Gastroenterology 86 (1984) 654-661
34. Loesch A., Belai A., Lincoln J., and Burnstock G. Enteric nerves in diabetic rats: electron microscopic evidence for neuropathy of vasoactive intestinal polypeptide-containing fibres. Acta Neuropathol. 70 (1986) 161-168
35. Mawe G.M., and Gershon M.D. Functional heterogeneity in the myenteric plexus: demonstration using cytochrome oxidase as a verified cytochemical probe of the activity of individual enteric neurons. J. Comp. Neurol. 249 (1986) 381-391
36. Oates P.J. Polyol pathway and diabetic peripheral neuropathy. Int. Rev. Neurobiol. 50 (2002) 325-392
37. Pittenger G., and Vinik A. Nerve growth factor and diabetic neuropathy. Exp. Diabesity Res. 4 (2003) 271-285
38. Price D.L., Rhett P.M., Thorpe S.R., and Baynes J.W. Chelating activity of advanced glycation end-product inhibitors. J. Biol. Chem. 276 (2001) 48967-48972
39. Samsom M., and Smout A.J. Abnormal gastric and small intestinal motor function in diabetes mellitus. Dig. Dis. Res. 15 (1997) 263-274
40. Schmidt R.E. Neuropathology and pathogenesis of diabetic autonomic neuropathy. Int. Rev. Neurobiol. 50 (2002) 258-292
41. Schmidt R.E., Dorsey D.A., Beaudet L.N., Reiser K.M., Williamson J.R., and Tilton R.G. Effect of aminoguanidine on the frequency of neuroaxonal dystrophy in the superior mesenteric sympathetic autonomic ganglia of rats with streptozocin-induced diabetes. Diabetes 45 (1996) 284-290
42. Semra Y.K., Smith N.C., and Lincoln J. Comparative effects of high glucose on different adult sympathetic neurons in culture. NeuroReport 15 (2004) 2321-2325
43. Shotton H.R., and Lincoln J. Diabetes only affects nitric oxide synthase-containing myenteric neurons that do not contain heme oxygenase 2. Brain Res. 1068 (2006) 248-256
44. Shotton H.R., Clarke S., and Lincoln J. The effectiveness of treatments of diabetic autonomic neuropathy is not the same in autonomic nerves supplying different organs. Diabetes 52 (2003) 157-164
45. Shotton H.R., Broadbent S., and Lincoln J. Prevention and partial reversal of diabetes-induced changes in enteric nerves of the rat ileum by combined treatment with α-lipoic acid and evening primrose oil. Auton. Neurosci. : Basic Clin. 111 (2004) 57-65
46. Singh R., Barden A., Mori T., and Beilin L. Advanced glycation end products: a review. Diabetologia 44 (2001) 129-146
47. Spångéus A., Suhr O., and El-Salhy M. Diabetic state affects the innervation of the gut in an animal model of human type 1 diabetes. Histol. Histopathol. 15 (2000) 739-744
48. Ueda S., Aikawa M., Ishizuya-Oka A., Yamaoka S., Koibuchi N., and Yoshimoto K. Age-related dopamine deficiency in the mesostriatal dopamine system of zitter mutant rats: regional fiber vulnerability in the striatum and the olfactory tubercle. Neurosci. 95 (2000) 389-398
49. Usta M.F., Bivalacqua T.J., Koksal I.T., Toptas B., Surmen S., and Hellstrom W.J. The protective effect of aminoguanidine on erectile function in diabetic rats is not related to the timing of treatment. Brit. J. Urol. Int. 94 (2004) 429-432
50. Vincent A.M., Russell J.W., Low P., and Feldman E.L. Oxidative stress in the pathogenesis of diabetic neuropathy. Endocr. Rev. 25 (2004) 612-628
51. Vlassara H., and Palace M.R. Diabetes and advanced glycation endproducts. J. Intern. Med. 251 (2000) 87-101
52. Vlassara H., Brownlee M., and Cerami A. Nonenzymatic glycosylation of peripheral nerve protein in diabetes mellitus. Proc. Natl. Acad. Sci. U. S. A. 78 (1981) 5190-5192
53. Watabe Y., Yoshimoto K., Eguchi M., and Ueda S. Degeneration of monoaminergic fibers in the aged micrencephalic rat. Neurosci. Lett. 385 (2005) 82-86
54. West I.C. Radicals and oxidative stress in diabetes. Diabet. Med. 17 (2000) 171-180
55. Wrzos H.F., Cruz A., Polavarapu R., Shearer D., and Ouyang A. Nitric oxide synthase (NOS) expression in the myenteric plexus of streptozotocin-diabetic rats. Dig. Dis. Sci. 42 (1997) 2106-2110
56. Yagihashi S., Kamijo M., Yagihashi N., Baba M., and Nagai K. Effect of aminoguanidine on functional and structural abnormalities in peripheral nerve of STZ-induced diabetic rats. Diabetes 41 (1992) 47-52
57. Yorek M.A. The role of oxidative stress in diabetic vascular and neural disease. Free Radic. Res. 37 (2003) 471-480
58. Zanoni J.N., Buttow N.C., Bazotte R.B., and Miranda Neto M.H. Evaluation of the population of NADPH-diaphorase-stained and myosin-V myenteric neurons in the ileum of chronically streptozotocin-diabetic rats treated with ascorbic acid. Auton. Neurosci. 104 (2003) 32-38