A different regional response by mouse oligodendrocyte progenitor cells (OPCs) to high-dose X-irradiation has consequences for repopulating OPC-depleted normal tissue

European Journal of Neuroscience

Volumn 25, Issue 2, 2007, Pages 417-424

  Irvine, Karen Amanda ^a   Blakemore, William F ^a  

^a Department of Veterinary Medicine   (United Kingdom)

Author keywords

CNS; NG2; Oligodendrocyte progenitor cells; Stem cells; X irradiation

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CELL LOSS; CELL POPULATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CORPUS CALLOSUM; DIENCEPHALON; FEMALE; HIPPOCAMPUS; MESENCEPHALON; MOUSE; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RADIATION DOSE; SPINAL CORD; STEM CELL; TELENCEPHALON; X IRRADIATION;

ANIMALS; ANTIGENS; BRAIN; BROMODEOXYURIDINE; FEMALE; GREEN FLUORESCENT PROTEINS; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; OLIGODENDROGLIA; PROTEOGLYCANS; STEM CELL TRANSPLANTATION; STEM CELLS; X-RAYS;

EID: 33847034147     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2007.05313.x     Document Type: Article

References (28)

1. Ben Hur, T., Einstein, O., Mizrachi-Kol, R., Ben Menachem., O., Reinhartz, E., Karussis, D. & Abramsky, O. (2003) Transplanted multipotential neural precursor cells migrate into the inflamed white matter in response to experimental autoimmune encephalomyelitis. Glia, 41, 73-80.
2. Chari, D.M. & Blakemore, W.F. (2002) Efficient recolonisation of progenitor-depleted areas of the CNS by adult oligodendrocyte progenitor cells. Glia, 37, 307-313.
3. Chari, D.M., Gilson, J.M., Franklin, R.J. & Blakemore, W.F. (2006) Oligodendrocyte progenitor cell (OPC) transplantation is unlikely to offer a means of preventing X-irradiation induced damage in the CNS. Exp. Neurol., 198, 145-153.
4. Chari, D.M., Huang, W.L. & Blakemore, W.F. (2003) Dysfunctional oligodendrocyte progenitor cell (OPC) populations may inhibit repopulation of OPC depleted tissue. J. Neurosci. Res., 73, 787-793.
5. Einstein, O., Ben Menachem., O., Mizrachi-Kol, R., Reinhartz, E., Grigoriadis, N. & Ben Hur, T. (2006) Survival of neural precursor cells in growth factor-poor environment: implications for transplantation in chronic disease. Glia, 53, 449-455.
6. Foote, A.K. & Blakemore, W.F. (2005) Repopulation of oligodendrocyte progenitor cell depleted tissue in a model of chronic demyelination. Neuropathol. Appl. Neurobiol., 31, 105-114.
7. Franklin, R.J., Bayley, S.A. & Blakemore, W.F. (1996) Transplanted CG4 cells (an oligodendrocyte progenitor cell line) survive, migrate, and contribute to repair of areas of demyelination in X-irradiated and damaged spinal cord but not in normal spinal cord. Exp. Neurol., 137, 263-276.
8. He, W., Ingraham, C., Rising, L., Goderie, S. & Temple, S. (2001) Multipotent stem cells from the mouse basal forebrain contribute GABAergic neurons and oligodendrocytes to the cerebral cortex during embryogenesis. J. Neurosci., 21, 8854-8862.
9. Jones, L.L., Yamaguchi, Y., Stallcup, W.B. & Tuszynski, M.H. (2002) NG2 is a major chondroitin sulfate proteoglycan produced after spinal cord injury and is expressed by macrophages and oligodendrocyte progenitors. J. Neurosci., 22, 2792-2803.
10. Kessaris, N., Fogarty, M., Iannarelli, P., Grist, M., Wegner, M. & Richardson, W.D. (2005) Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage. Nature Neurosci., 9, 173-179.
11. Kitada, M. & Rowitch, D.H. (2006) Transcription factor co-expression patterns indicate heterogeneity of oligodendroglial subpopulations in adult spinal cord. Glia, 54, 35-46.
12. Lachapelle, F., Avellana-Adalid, V., Nait-Oumesmar, B. & Baron-Van Evercooren, A. (2002) Fibroblast growth factor-2 (FGF-2) and platelet-derived growth factor AB (PDGF AB) promote adult SVZ-derived oligodendrogenesis in vivo. Mol. Cell Neurosci., 20, 390-403.
13. Le Bras, B., Chatzopoulou, E., Heydon, K., Martinez, S., Ikenaka, K., Prestoz, L., Spassky, N., Zalc, B. & Thomas, J.L. (2005) Oligodendrocyte development in the embryonic brain: the contribution of the plp lineage. Int. J. Dev. Biol., 49, 209-220.
14. Levine, J.M. (1994) Increased expression of the NG2 chondroitin-sulfate proteoglycan after brain injury. J. Neurosci., 14, 4716-4730.
15. Levine, J.M. & Stallcup, W.B. (1987) Plasticity of developing cerebellar cells in vitro studied with antibodies against the NG2 antigen. J. Neurosci., 7, 2721-2731.
16. Levine, J.M., Stincone, F. & Lee, Y.S. (1993) Development and differentiation of glial precursor cells in the rat cerebellum. Glia, 7, 307-321.
17. Ligon, K.L., Kesari, S., Kitada, M., Sun, T., Arnett, H.A., Alberta, J.A., Anderson, D.J., Stiles, C.D. & Rowitch, D.H. (2006) Development of NG2 neural progenitor cells requires Olig gene function. Proc. Natl Acad. Sci. USA, 103, 7853-7858.
18. McTigue, D.M., Weim, P. & Stokes, B.T. (2001) Proliferation of NG2-positive cells and altered oligodendrocyte numbers in the contused rat spinal cord. J. Neurosci., 21, 3392-3400.
19. Nishiyama, A., Lin, X.H., Giese, N., Heldin, C.H. & Stallcup, W.B. (1996a) Co-localization of NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells in the developing rat brain. J. Neurosci. Res., 43, 299-314.
20. Nishiyama, A., Lin, X.H., Giese, N., Heldin, C.H. & Stallcup, W.B. (1996b) Interaction between NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells is required for optimal response to PDGF. J.Neurosci. Res., 43, 315-330.
21. O'Leary, M.T. & Blakemore, W.F. (1997) Oligodendrocyte precursors survive poorly and do not migrate following transplantation into the normal adult central nervous system. J. Neurosci. Res., 48, 159-167.
22. Olivier, C., Cobos, I., Perez Villegas, E.M., Spassky, N., Zalc, B., Martinez, S. & Thomas, J.L. (2001) Monofocal origin of telencephalic oligodendrocytes in the anterior entopeduncular area of the chick embryo. Development, 128, 1757-1769.
23. Ong, W.Y. & Levine, J.M. (1999) A light and electron microscope study of NG2 chondroitin-sulfate proteoglycan-positive oligodendrocyte precursor cells in the normal and kainite-lesioned rat hippocampus. Neuroscience, 92, 83-95.
24. Polito, A. & Reynolds, R. (2005) NG2-expressing cells as oligodendrocyte progenitors in the normal and demyelinated adult central nervous system. J. Anat., 207, 707-716.
25. Rasband, W.S. (1997-2006) ImageJ. US National Institutes of Health, Bethesda, MD, http://rsb.info.nih.gov/ij/.
26. Shinomiya, N. (2001) New concepts in radiation-induced apoptosis: 'premitotic apoptosis' and 'postmitotic apoptosis'. J. Cell Mol. Med., 5, 240-253.
27. Spassky, N., Goujet-Zalc, C., Parmantier, E., Olivier, C., Martinez, S., Ivanova, A., Ikenaka, K., Macklin, W., Cerruti, I., Zalc, B. & Thomas, J.L. (1998) Multiple restricted origin of oligodendrocytes. J. Neurosci., 18, 8331-8343.
28. Stallcup, W.B. & Beasley, L. (1987) Bipotential glial precursor cells of the optic nerve express the NG2 proteoglycan. J. Neurosci., 7, 2737-2744.