Selective roles for α-PKC in positive signaling for O2- generation and calcium mobilization but not elastase release in differentiated HL60 cells

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1773, Issue 3, 2007, Pages 440-449

  Korchak, Helen M ^a   Dorsey, Lindsay B ^a   Li, Haiying ^a   Mackie, DeMauri ^a   Kilpatrick, Laurie E ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

PKC; Ca2+ signaling; Degranulation; O2 generation; p47phox

Indexed keywords

CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; ELASTASE; FORMYLMETHIONYLLEUCYLPHENYLALANINE; LIGAND; OXIDE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN P47; SMALL INTERFERING RNA;

ARTICLE; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CELL DIFFERENTIATION; CELL STRAIN HL 60; CONTROLLED STUDY; DEGRANULATION; ENZYME RELEASE; HUMAN; HUMAN CELL; NEUTROPHIL; PHAGOCYTE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

CALCIUM; CALCIUM SIGNALING; CELL DIFFERENTIATION; CELL MEMBRANE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HL-60 CELLS; HUMANS; ISOENZYMES; LIGANDS; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NADPH OXIDASE; PANCREATIC ELASTASE; PHORBOL ESTERS; PHOSPHORYLATION; PROTEIN KINASE C-ALPHA; PROTEIN TRANSPORT; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SUPEROXIDES;

EID: 33847033768     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2006.10.007     Document Type: Article

References (53)

1. Babior B.M., Lambeth J.D., and Nauseef W. The neutrophil NADPH oxidase. Arch. Biochem. Biophys. 397 (2002) 342-344
2. Burg N.D., and Pillinger M.H. The neutrophil function and regulation in innate and humoral immunity. Clin. Immunol. 99 (2001) 7-17
3. Dinauer M.C. Regulation of neutrophil function by RacGTPases. Curr. Opin. Hematol. 10 (2003) 8-15
4. phox phosphorylation and translocation in activated human monocytes. J. Immunol. 173 (2004) 5730-5738
5. - generation but not degranulation or adherence in differentiated HL60 cells. J. Biol. Chem. 273 (1998) 27292-27299
6. Mellor H., and Parker P.J. The extended protein kinase C family (Review). Biochem. J. 332 (1998) 281-292
7. Parker P.J., and Murray-Rust J. PKC at a glance. J. Cell Sci. 117 (2004) 131-132
8. Kent J.D., Sergeant S., Burns D.J., and McPhail L.C. Identification and regulation of protein kinase C-delta in human neutrophils. J. Immunol. 157 (1996) 4641-4647
9. Korchak H.M., and Kilpatrick L.E. Roles for βII-PKC and RACK1 in positive and negative signaling for superoxide anion generation in differentiated HL60 cells. J. Biol. Chem. 276 (2001) 8910-8917
10. Majumdar S., Kane L.H., Rossi M.W., Volpp B.D., Nauseef W.M., and Korchak H.M. Protein kinase C isotypes and signal-transduction in human neutrophils: selective substrate specificity of calcium-dependent β-PKC and novel calcium-independent nPKC. Biochim. Biophys. Acta 1176 (1993) 276-286
11. Sergeant S., and McPhail L.C. Opsonized zymosan stimulates the redistribution of protein kinase C isoforms in human neutrophils. J. Immunol. 159 (1997) 2877-2885
12. Wooten M.W., Seibenhener M.L., and Soh Y. Expression of protein kinase C isoforms in HL60 and phorbol ester resistant HL525 cells. Cytobios 76 (1993) 19-29
13. Sengelov H., Kjeldsen L., and Borregaard N.H. Control of exocytosis in early neutrophil activation. J. Immunol. 150 (1993) 1535-1543
14. Berridge M., Lipp P., and Bootman M. Calcium signaling. Curr. Biol. 9 (1999) R157-R158
15. Cockcroft S., Barrowman M.M., and Gomperts B.D. Breakdown and synthesis of polyphosphoinositides in fMet-Leu-Phe-stimulated neutrophils. FEBS Lett. 181 (1985) 259-263
16. Korchak H.M., Vosshall L.B., Zagon G., Ljubich P., Rich A.M., and Weissmann G. Activation of the neutrophil by calcium-mobilizing ligands: I. A chemotactic peptide and the lectin concanavalin a stimulate superoxide anion generation but elicit different calcium movements and phosphoinositide remodelling. J. Biol. Chem. 263 (1988) 11090-11097
17. Korchak H.M., Vosshall L.B., Haines K.A., Wilkenfeld C., Lundquist K.F., and Weissmann G. Activation of the human neutrophil by calcium mobilizing ligands: II. Correlation of calcium, diacyl glycerol and phosphatidic acid generation with superoxide anion generation. J. Biol. Chem. 263 (1988) 11098-11105
18. 2+influx across the plasma membrane of HL-60 cells. A role for cytosolic free calcium elevations and inositol 1,3,4,5-tetrakisphosphate production. J. Biol. Chem. 264 (1989) 7251-7261
19. Putney J.W. "Kissin' cousins": Intimate plasma membrane-ER interactions underlie capacitative calcium entry. Cell 99 (1999) 5-8
20. Schaefer M., Plant T.D., Obukhov G.O., Hofmann T., Gudermann T., and Schultz G. Receptor-mediated regulation of the nonselective cation channels TRPC4 and TRPC5. J. Biol. Chem. 275 (2000) 17517-17526
21. 2+-ATPases. TIPS 19 (1998) 131-135
22. Gallin E.K. Ion channels in leukocytes. Physiol. Rev. 71 (1991) 775-811
23. von Tscharner V., Prod'hom B., Baggiolini M., and Reuter H. Ion channels in human neutrophils are activated by a rise in the free cytosolic calcium concentration. Nature 324 (1986) 369-372
24. 2+uptake by βII-PKC in differentiated HL60 cells. Am. J. Physiol. 281 (2001) C514-C523
25. 2+ entry pathway in differentiated HL60 cells. J. Biol. Chem. 269 (1994) 29451-29456
26. + in the activation of beta-glucuronidase release and superoxide production. Biochem. J. 288 (1992) 1025-1035
27. Curnutte J.T., Erickson R.W., Ding J., and Badwey J.A. Reciprocal interactions between protein kinase C and components of the NADPH oxidase complex may regulate superoxide production by neutrophils stimulated with a phorbol ester. J. Biol. J. Biol. Chem. 269 (1994) 10813-10819
28. Iyer S.S., Pearson D.W., Nauseef W.M., and Clark R.A. Evidence for a readily dissociable complex of p47phox and p67phox in cytosol of unstimulated human neutrophils. J. Biol. Chem. 269 (1994) 22405-22411
29. Mizrahi A., Berdichevsky Y., Ugolev Y., Molshanski-Mor S., Nakash Y., Dahan I., Alloul N., Gorzalczany Y., Sarfstein R., Hirshberg M., and Pick E. Assembly of the phagocyte NADPH oxidase complex: chimeric constructs derived from the cytosolic components as tools for exploring structure-function relationships. J. Leukocyte Biol. 79 (2006) 881-895
30. Nauseef W.M., Volpp B.B., McCormick S., Leidal K.G., and Clark R.A. Assembly of the neutrophil respiratory burst oxidase. Protein kinase C promotes cytoskeletal and membrane association of cytosolic oxidase components. J. Biol. Chem. 266 (1991) 5911-5917
31. Sumimoto H., Hata K., Mizuku K., Ito T., Kage Y., Sakaki Y., Fukimaki M., and Takeshige K. Assembly and activation of the phagocyte NADPH oxidase. Specific interaction of the N-terminal Src homology 3 domain of p47phox with p22 phox is required for activation of the NADPH oxidase. J. Biol. Chem. 271 (1996) 22152-22158
32. Tisch D., Halpern M., Marciano D., Kloog Y., and Aviram I. Activation of signaling pathways in HL60 cells and human neutrophils by farnesylthiosalicylate. Eur. J. Biochem. 242 (1996) 529-536
33. Fontayne A., Dang P.M., Gougerot-Pocidalo M.-A., and El Benna J. Phosphorylation of p47phox sites by PKCα, βII, δ and ζ: Effect on binding to p22phox and on NADPH oxidase activation. Biochemistry 41 (2002) 7743-7750
34. Dekker L.V., Leitges M., Altschuler G., Mistry N., McDermott A., Roes J., and Segal A.W. Protein kinse C-beta contributes to NADPH oxidase activation in neutrophils. Biochem. J. 347 (2000) 285-289
35. Larsen E.C., DiGennaro J.A., Saito N., Mehta S., Loegering D.J., Mazurkiewicz J.E., and Lennarz M.R. Differential requirement for classic and novel PKC isoforms in respiratory burst and phagocytosis in RAW264.7 cells. J. Immunol. 165 (2000) 2809-2817
36. - production and low density lipoprotein lipid oxidation. J. Biol. Chem. 274 (1999) 3764-3771
37. He R., Nanamori M., Sang H., Yin H., Dinauer M.C., and Ye R.D. Reconstitution of chemotactic peptide-induced nicotinamide adenine dinucleotide phosphate (reduced) oxidase activation in transgenic COS-phox cells. J. Immunol. 173 (2004) 7462-7470
38. Irie N., Sakai N., Ueyama T., Kajimoto T., Shirai Y., and Saito N. Subtype- and species-specific knockdown of PKC using short interfering RNA. Biochem. Biophys. Res. Commun. 298 (2002) 738-743
39. Kilpatrick L.E., Sun S., Mackie D., Baik F., Li H., and Korchak H.M. Regulation of TNF Mediated Anti-Apoptotic Signaling in Human Neutrophils: Role of δ-PKC and ERK1/2. J. Leukoc. Biol. 80 (2006) 1512-1521
40. Melkonyan H., Sorg C., and Klempt M. Electroporation efficiency in mammalian cells is increased by dimethyl sulfoxide (DMSO). Nucleic Acid Res. 24 (1996) 4356-4357
41. Grynkiewicz G., Poenie M., and Tsien R.Y. J. Biol. Chem. 260 (1985) 3440-3450
42. 2+entry pathway of human neutrophils. J. Biol. Chem. 269 (1994) 3963-3967
43. 2+ entry. J. Biol. Chem. 272 (1997) 21831-21838
44. Harper J.L., Camerini-Otero C.S., Li A.-H., Kim S.-A., Jacobson K.A., and Daly J.W. Dihydropyridines as inhibitors of capacitative calcium entry in leukemic HL-60 cells. Biochem. Pharmacol. 65 (2003) 329-338
45. Dang P.M., Fontayne A., Hakim J., El Benna J., and Perianin A. Protein kinase C phosphorylates a subset of selective sites of the NADPH oxidase component p47phox and participates in formyl peptide-mediated neutrophil respiratory burst. J. Immunol. 166 (2001) 1206-1213
46. Phillips W.A., Fujiki T., Rossi M.W., Korchak H.M., and Johnston Jr. R.B. Influence of calcium on the subcellular distribution of protein kinase C in human neutrophils. J. Biol. Chem. 264 (1989) 8361-8365
47. Adams E.R., Dratz E.A., Gizachew D., Deleo F.R., Volpp B.D., Vlases M., Jesaitis A.J., and Quinn M.T. Interaction of human neutrophil flavocytochrome b with cytosolic proteins: transferred-NOESY NMR studies of gp91phox C-terminal peptide bound to p47phox. Biochem. J. 325 (1997) 249-257
48. Nishikawa K., Toker A., Johannes F.J., Songyang Z., and Cantley L.C. Determination of the specific substrate sequence motifs of protein kinase C isozymes. J. Biol. Chem. 272 (1997) 952-960
49. Faust L.R.P., El Benna J., Babior B.M., and Chanock S.J. The phosphorylation targets of p47phox, a subunit of the respiratory burst oxidase. Functions of the individual target serines as evaluated by site-directed mutagenesis. J. Clin. Invest. 96 (1995) 1499-1505
50. Holmberg C.I., Tran S.E.F., Eriksson J.E., and Sistonen L. Multisite phosphorylation provides sophisticated regulation of transcription factors. Trends Biochem. Sci. 27 (2002) 619-627
51. Hoyal C.R., Gutierrez A., Young B.M., Catz S.D., Lin J.-H., Tsichlis P.N., and Babior B.M. Modulation of p47phox activity by site-specific phosphorylation: Akt-dependent activation of the NADPH oxidase. Proc. Natl. Acad. Sci. 100 (2003) 5130-5135
52. Korchak H.M., Wilkenfeld C., Rich A.M., Radin A.R., Vienne K., and Rutherford L.E. Stimulus response coupling in the human neutrophil. Differential requirements for receptor occupancy in neutrophil responses to a chemoattractant. J. Biol. Chem. 259 (1984) 7439-7445
53. Lee C., Xu D.Z., Feketeova E., Kannan K.B., Fekete Z., Deitch E.A., Livingston D.H., and Hauser C.J. Store-operated calcium channel inhibition attenuates neutrophil function and postshock acute lung injury. J. Trauma 59 (2005) 56-63