Imiquimod as an antiaging agent

Journal of the American Academy of Dermatology

Volumn 56, Issue 3, 2007, Pages 422-425

  Metcalf, Sara ^a   Crowson, A Neil ^b   Naylor, Mark ^b   Haque, Raashid ^c   Cornelison, Raymond ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF OKLAHOMA   (United States)

^c Wichita Clinic   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; IMIQUIMOD; MELANIN;

ACANTHOSIS; ARTICLE; CELL POPULATION; CLINICAL ARTICLE; CLINICAL TRIAL; CREAM; DRUG EFFICACY; DRUG WITHDRAWAL; ELASTOSIS; EPIDERMIS; HISTOLOGY; HUMAN; HUMAN TISSUE; INFLAMMATION; MALIGNANT LENTIGO; PRIORITY JOURNAL; SKIN ATROPHY; SKIN BIOPSY; SKIN DEFECT; SKIN IRRITATION; SKIN ULCER; THICKNESS;

AMINOQUINOLINES; ANTINEOPLASTIC AGENTS; CELL COUNT; COLLAGEN; DERMIS; DRUG ADMINISTRATION SCHEDULE; EPIDERMIS; HUMANS; HUTCHINSON'S MELANOTIC FRECKLE; MELANINS; MELANOCYTES; OINTMENTS; SKIN AGING; SKIN NEOPLASMS;

EID: 33847020405     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaad.2006.10.034     Document Type: Article

References (12)

1. Stratigos A.J., and Katsambas A.D. The role of topical retinoids in the treatment of photoaging. Drugs 65 (2005) 1061-1072
2. Naylor M.F., Crowson N., Kuwahara R., Teague K., Garcia C., Mackinnis C., et al. Treatment of lentigo maligna with topical imiquimod. Br J Dermatol 149 (2003) 66-69
3. Crowson A.N., Metcalf S., Naylor M.F., Magro C.M., Haque R., Garcia C., and Cornelison R.L. Lentigo maligna: The dermatopathologic effects of topical Imiquimod therapy. Lab Invest 84 suppl 1 (2004) 92A
4. Crowson A.N., Magro C.M., and Mihm Jr. M.C. The melanocytic proliferations: a comprehensive textbook of pigmented lesions (2001), John Wiley and Sons, New York pp. 281-397
5. Fisher G.J., Kang S., Varani J., Bata-Csorgo Z., Wan Y., Datta S., et al. Mechanisms of photoaging and chronological skin aging. Arch Dermatol 138 (2002) 1462-1470
6. Yaar M., and Eller M.S. Mechanisms of aging. Arch Dermatol 138 (2002) 1429-1431
7. Hemmi H., Kaisho T., Takeuchi O., Sato S., Sanjo H., Hoshino K., et al. Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat Immunol 3 (2002) 196-200
8. Hesling C., D'Incan M., Mansard S., Franck F., Corbin-Duval A., Chevenet C., et al. In vivo and in situ modulation of the expression of genes involved in metastasis and angiogenesis in a patient treated with topical imiquimod for melanoma skin metastases. Br J Dermatol 150 (2004) 761-767
9. Li V.W., Li W.W., Talcott K.E., and Zhai A.W. Imiquimod as an antiangiogenic agent. J Drugs Dermatol 4 (2005) 708-715
10. Lain E.L., and Carrington P.R. Imiquimod treatment of exuberant granulation tissue in a nonhealing diabetic ulcer. Arch Dermatol 141 (2005) 1368-1370
11. Kang S., Kauls L.S., and Gaspari A.A. Toll-like receptors: applications to dermatologic disease. J Am Acad Dermatol 54 (2006) 951-983
12. Takeda K., and Akira S. TLR signaling pathways. Semin Immunol 16 (2004) 3-9