The nociceptin/orphanin FQ receptor antagonist J-113397 and L-DOPA additively attenuate experimental Parkinsonism through overinhibition of the nigrothalamic pathway

Journal of Neuroscience

Volumn 27, Issue 6, 2007, Pages 1297-1307

  Marti, Matteo ^a   Trapella, Claudio ^a   Viaro, Riccardo ^a   Morari, Michele ^a  

^a UNIVERSITY OF FERRARA   (Italy)

Author keywords

6 OHDA; J 113397; L DOPA; Microdialysis; Nociceptin; Parkinson's disease

Indexed keywords

1 (1 CYCLOOCTYLMETHYL 3 HYDROXYMETHYL 4 PIPERIDYL) 3 ETHYL 1,3 DIHYDRO 2H BENZIMIDAZOL 2 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; BENSERAZIDE; BICUCULLINE; GLUTAMIC ACID; LEVODOPA; NOCICEPTIN RECEPTOR ANTAGONIST; OXIDOPAMINE; SODIUM CHANNEL BLOCKING AGENT; TETRODOTOXIN;

4 AMINOBUTYRIC ACID RELEASE; AKINESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN DAMAGE; BRAIN REGION; CONTROLLED STUDY; DRUG DOSE COMPARISON; MALE; MICRODIALYSIS; NERVE TRACT; NEUROBIOLOGY; NEUROTRANSMISSION; NONHUMAN; PARKINSONISM; PRIORITY JOURNAL; RAT; SUBSTANTIA NIGRA; SYNAPTIC INHIBITION; THALAMUS; THALAMUS VENTRAL NUCLEUS;

ANIMALS; ANTIPARKINSON AGENTS; BENZIMIDAZOLES; BICUCULLINE; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; INJECTIONS; LEVODOPA; MALE; MICRODIALYSIS; MOTOR ACTIVITY; MUSCULOSKELETAL EQUILIBRIUM; NEURAL PATHWAYS; OXIDOPAMINE; PARKINSONIAN DISORDERS; PERFUSION; PIPERIDINES; PSYCHOMOTOR PERFORMANCE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; RECEPTORS, OPIOID; SODIUM CHANNEL BLOCKERS; STEREOTAXIC TECHNIQUES; SUBSTANTIA NIGRA; TETRODOTOXIN; THALAMUS;

EID: 33847003007     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4346-06.2007     Document Type: Article

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