메뉴 건너뛰기




Volumn 2006 B, Issue , 2006, Pages 997-1002

The development of integrated microfluidic chemistry platforms for lead optimisation in the pharmaceutical industry

Author keywords

[No Author keywords available]

Indexed keywords

DRUG PRODUCTS PLANTS; HEAT TRANSFER; LEAD; MASS TRANSFER; OPTIMIZATION; TOXIC MATERIALS;

EID: 33846998340     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1115/icnmm2006-96058     Document Type: Conference Paper
Times cited : (5)

References (20)
  • 1
    • 23944467551 scopus 로고    scopus 로고
    • Leveraging the advantages offered by microfluidics to enhance the drug discovery process
    • Wong-Hawkes, S.Y.F.; Chapela, M.J.V., Montembault, M.; Leveraging the advantages offered by microfluidics to enhance the drug discovery process, QSAR Comb. Sci., 24, (2005), 712-721.
    • (2005) QSAR Comb. Sci , vol.24 , pp. 712-721
    • Wong-Hawkes, S.Y.F.1    Chapela, M.J.V.2    Montembault, M.3
  • 3
    • 33846960967 scopus 로고    scopus 로고
    • Hughes, I, Warrington, B.H, Wong, S.Y.F, Microfluidic system, Glaxo Group Limited, 2004, WO 089533 A1
    • Hughes, I.; Warrington, B.H.; Wong, S.Y.F.; Microfluidic system, (Glaxo Group Limited), (2004), WO 089533 A1.
  • 4
    • 15944417098 scopus 로고    scopus 로고
    • Organic Synthesis with Microstructured Reactors
    • Hessel, V.; Lowe, H.; Organic Synthesis with Microstructured Reactors, Chemical Engineering Technol, 28 (2005), 267-284.
    • (2005) Chemical Engineering Technol , vol.28 , pp. 267-284
    • Hessel, V.1    Lowe, H.2
  • 5
    • 0001263415 scopus 로고    scopus 로고
    • Microfabricated devices for Fluid Mixing and Their Application for Chemical Synthesis
    • Kakuta, M.; Bessoth, F.G.; Manz, A.; Microfabricated devices for Fluid Mixing and Their Application for Chemical Synthesis, The Chemical Record, 1, (2001), 395-405.
    • (2001) The Chemical Record , vol.1 , pp. 395-405
    • Kakuta, M.1    Bessoth, F.G.2    Manz, A.3
  • 6
    • 0032565948 scopus 로고    scopus 로고
    • Smaller, faster chemistry
    • Jensen, K., Smaller, faster chemistry, Nature, 393, (1998), 735-736.
    • (1998) Nature , vol.393 , pp. 735-736
    • Jensen, K.1
  • 7
    • 9944240339 scopus 로고    scopus 로고
    • Chemical microprocess technology-from laboratory-scale to production
    • (a) Pennemann, H.; Hessel, V; Lowe, H.; Chemical microprocess technology-from laboratory-scale to production, Chem. Eng. Sci., 59 (2004), 4789-4794.
    • (2004) Chem. Eng. Sci , vol.59 , pp. 4789-4794
    • Pennemann, H.1    Hessel, V.2    Lowe, H.3
  • 8
    • 15944429349 scopus 로고    scopus 로고
    • Process Intensification by Miniaturization
    • (b) Charpentier J-C.; Process Intensification by Miniaturization, Chem. Eng. Technol., 28 (2005), 255-258.
    • (2005) Chem. Eng. Technol , vol.28 , pp. 255-258
    • Charpentier, J.-C.1
  • 9
    • 0141961502 scopus 로고    scopus 로고
    • A Hantzsch synthesis of 2-aminothiazoles performed in a heated microreactor system
    • Garcia-Egido, E.; Wong, S.Y.F.; Warrington, B.H.; A Hantzsch synthesis of 2-aminothiazoles performed in a heated microreactor system, Lab Chip, 2, (2002), 31-33.
    • (2002) Lab Chip , vol.2 , pp. 31-33
    • Garcia-Egido, E.1    Wong, S.Y.F.2    Warrington, B.H.3
  • 10
    • 0038536135 scopus 로고    scopus 로고
    • Synthesis of a three-member array of cycloadducts in a glass microchip under pressure driven flow
    • Fernandez-Suarez, M.; Wong, S.Y.F.; Warrington, B.H.; Synthesis of a three-member array of cycloadducts in a glass microchip under pressure driven flow, Lab Chip, 2, (2002), 170-174.
    • (2002) Lab Chip , vol.2 , pp. 170-174
    • Fernandez-Suarez, M.1    Wong, S.Y.F.2    Warrington, B.H.3
  • 11
    • 0442312891 scopus 로고    scopus 로고
    • Synthesis and analysis of combinatorial libraries performed in an automated micro reactor system
    • Garcia-Egido, E.; Spikmans, V.; Wong, S.Y. F.; Warrington, B.H., Synthesis and analysis of combinatorial libraries performed in an automated micro reactor system, Lab Chip, 3, (2003), 73-76.
    • (2003) Lab Chip , vol.3 , pp. 73-76
    • Garcia-Egido, E.1    Spikmans, V.2    Wong, S.Y.F.3    Warrington, B.H.4
  • 12
    • 33846953404 scopus 로고    scopus 로고
    • Fernandez-Suarez, M.: Unpublished results. 12. Varma, R.S.; Kabalka, G.W., Selective reduction of α,β-unsaturated nitrocompounds with sodium borohydryde in methanolic solutions: a facile route to nitroalkanes, Synth. Comm., 15, (1985), 151-155.
    • Fernandez-Suarez, M.: Unpublished results. 12. Varma, R.S.; Kabalka, G.W., Selective reduction of α,β-unsaturated nitrocompounds with sodium borohydryde in methanolic solutions: a facile route to nitroalkanes, Synth. Comm., 15, (1985), 151-155.
  • 13
    • 33846996203 scopus 로고    scopus 로고
    • Unpublished results
    • Garcia-Egido, E.; Unpublished results.
    • Garcia-Egido, E.1
  • 14
    • 0345724835 scopus 로고    scopus 로고
    • Identification from a combinatorial library of a small molecule that selectively induces apoptosis in cancer cells
    • Nesterenko, V.; Putt, K.S.; Hergenrother, P.J., Identification from a combinatorial library of a small molecule that selectively induces apoptosis in cancer cells, J. Am. Chem. Soc., 125, (2003), 14672-14673.
    • (2003) J. Am. Chem. Soc , vol.125 , pp. 14672-14673
    • Nesterenko, V.1    Putt, K.S.2    Hergenrother, P.J.3
  • 15
    • 0043123372 scopus 로고    scopus 로고
    • Synthesis of amide compounds of ferulic acid, and their stimulatory effects on insulin secretion in vitro
    • Nomura, E.; Kashiwada, A.; Hosoda, Asao.; Nakamura, K.; Morishita, H.; Tsuno, T.; Taniguchi, H., Synthesis of amide compounds of ferulic acid, and their stimulatory effects on insulin secretion in vitro, Bioorg. Med. Chem. 11, (2003), 3807-3813.
    • (2003) Bioorg. Med. Chem , vol.11 , pp. 3807-3813
    • Nomura, E.1    Kashiwada, A.2    Hosoda, A.3    Nakamura, K.4    Morishita, H.5    Tsuno, T.6    Taniguchi, H.7
  • 16
    • 0032970173 scopus 로고    scopus 로고
    • Vanilloid (Capsaicin) receptors and mechanisms
    • Szallasi, A.; Blumberg, P.M., Vanilloid (Capsaicin) receptors and mechanisms, Pharm, Rev. 51 (1999) 159-202.
    • (1999) Pharm, Rev , vol.51 , pp. 159-202
    • Szallasi, A.1    Blumberg, P.M.2
  • 17
    • 15944366532 scopus 로고    scopus 로고
    • Microreactor technology:A revolution for the fine chemical and pharmaceutical industries?
    • Roberge, D.M.; Ducry, L.; Bieler, N.; Cretton, P.; Zimmermann, B., Microreactor technology:A revolution for the fine chemical and pharmaceutical industries?, Chem. Eng. Technol., 28, (2005), 318-323.
    • (2005) Chem. Eng. Technol , vol.28 , pp. 318-323
    • Roberge, D.M.1    Ducry, L.2    Bieler, N.3    Cretton, P.4    Zimmermann, B.5
  • 19
    • 0037423435 scopus 로고    scopus 로고
    • Highly selective Friedel-Crafts monoalkylation using micromixing
    • Suga, S.; Nagaki, A.; Yoshida, J-I.; Highly selective Friedel-Crafts monoalkylation using micromixing, Chem. Commun., 2003, 354-355
    • (2003) Chem. Commun , pp. 354-355
    • Suga, S.1    Nagaki, A.2    Yoshida, J.-I.3
  • 20
    • 84875539226 scopus 로고    scopus 로고
    • preliminary results
    • work in progress
    • Garcia-Egido, E.; preliminary results, work in progress.
    • Garcia-Egido, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.