The effects of ethanolic leaf extract of Commiphora africana (Buseraceae) on lipid profile in rats

International Journal of Pharmacology

Volumn 2, Issue 6, 2006, Pages 618-622

  Adebayo, A H ^a   Aliyu, R ^b   Gatsing, D ^c   Garba, I H ^d  

^a Centre for Economic Policy and Development Research   (Nigeria)

^b UNIVERSITY OF JOS   (Nigeria)

^c UNIVERSITY OF DSCHANG   (Cameroon)

^d ABUBAKAR TAFAWA BALEWA UNIVERSITY   (Nigeria)

Author keywords

Anti cholesterolaemic; Anti lipidaemic; Commiphora africana; HDL cholesterol; LDL cholesterol

Indexed keywords

ALCOHOL; COMMIPHORA AFRICANA EXTRACT; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLACEBO; PLANT EXTRACT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARDIOVASCULAR DISEASE; CHOLESTEROL BLOOD LEVEL; COMMIPHORA; COMMIPHORA AFRICANA; CONTROLLED STUDY; DRUG DETERMINATION; DRUG DOSE COMPARISON; DRUG ISOLATION; DRUG MECHANISM; FEMALE; LIPID BLOOD LEVEL; NONHUMAN; PLANT LEAF; RAT; TRIACYLGLYCEROL BLOOD LEVEL; WISTAR RAT;

EID: 33846993037     PISSN: 18117775     EISSN: 18125700     Source Type: Journal    
DOI: 10.3923/ijp.2006.618.622     Document Type: Article

References (28)

1. Adewunmi, C.O. and J.A.O. Ojewole, 2004. Safety of traditional medicines, complementary and alternatives medicines in Africa. Afr. J. Trad. CAM., 1: 1-3.
2. Aliyu, R., D. Gatsing and H.S. Umar, 2002. Phytochemical screening and antimicrobial properties of ethanolic leave extract of Commiphora africana. West Afr. J. Biol. Sci., 13: 75-80.
3. Ayedoun, M.A., D.K. Sohounhloue, C. Menut, G. Lamaty, T. Molangui, J. Casanova and F. Tomi, 1998. Aromatic plants of tropical West Africa.VI. -α oxobisaboene as the main constituent of the leaf essential oil of Commiphora africana (A. Rich) Engl. from Benin. J. Essent. Oil. Res., 10: 105-107.
4. Braun, H.P., 1984. National cholesterol education programme. Recommendations for cholesterol measurements. Chemistry, 30: 991.
5. Choudhury, M.K., E.C. Johnson and A.S. Agbaji, 2000. Chemical investigation of the bark of Commiphora africana (Burseraceae). Ind. J. Pharm. Sci., 62: 311-312.
6. Dalziel, J.M. and J. Hutchinson, 1956. The Useful Plants of West Tropical Africa. 2nd Edn. London, Crown Agent for Overseas Government and Administration, pp: 112-132.
7. Edijala, J.K., S.O. Asagba, G.E. Eriyamremu and U. Atomatofa, 2005. Comparative effects of garden egg fruit, Oat and Apple on serum lipid profile in rats fed a high cholesterol diet. Pak. J. Nutr., 4: 245-249.
8. Eisenhauer, L.A., L.W. Nichols, R.T. Spencer and F.W. Bergan, 1998. Clinical Pharmacology and Nursing Management. Philadelphia, New York, Lippincott, pp: 449-462.
9. Gatsing, D., R. Aliyu, J.R. Kuiate, I.H. Garba, K.H. Jaryum, N. Tedongmo, M.F. Tchouanguep and G.I. Adoga, 2005. Toxicological evaluation of the aqueous extract of Allium sativum bulbs on laboratory mice and rats. Cameroon J. Exp. Biol., 01: 39-45.
10. Hanus, L.O., I. Rezanka, V.M. Dembitsky and A. Moussaieff, 2005. Myrrh-commiphora chemistry. Biomed Papers, 149: 3-28.
11. Hiller, A., 1987. National cholesterol education programme. Recommendations for HDL-cholesterol measurements. Clin. Chem., 33: 895.
12. Malhotra, S.C., M.M. Ahuja and R.S. Sundaram, 1977. Long term clinical studies on the hypolipidemic effect of Commiphora mukul (guggulu) and clofibrate. Ind. J. Med. Res., 65: 390-395.
13. Martinetz, D., 1993. The false myrrhe: African and Indian bdellium. Phytotherpy, 14: 34-36.
14. Michie, C.A. and E. Cooper, 1991. Frankincense and Myrrh as remedies in children. J. Roy. Soc. Med., 84: 602-605.
15. NCEP (National Cholesterol Education Programme), 1988. Expert panel on detection, evaluation and treatment of high blood cholesterol in adult. Arch. Intern. Med., 148: 66.
16. Nduka, N., 1999. Clinical Biochemistry for Students of Pathology. Animo Press, pp: 157-168.
17. Newall, C.A., L.A. Anderson and J.D. Philipson, 1996. Herbal Medicines: A Guide for Health Care Professionals. London, The Pharmaceutical Press, pp: 199-200.
18. Rang, H.P., M.M. Dale, J.M. Ritter and P. Gardner, 1995. Pharmacology. New York, Churchill-Livingstone.
19. Schafer, S., H. Hussein, G.R. Gershony, J.C. Rutledge and C.T. Kappagoda, 1997. Regression of severe atherosclerotic plague in individuals with mild elevation of LDL cholesterol. J. Invest. Med., 45: 536-541.
20. Smith, S.C., 2004. Heart diseases prevention must get more attention. World Health Federation, Circulation, pp: 1-2.
21. Srivastava, M., 1984. Effects of hypocholesterolemic agents of plant origin on Catecholamine biosynthesis in normal and cholesterol fed rabbits. J. BioSci., 6: 277-282.
22. Stein, E.A. and G.L. Meyers, 1995. National cholesterol education programme. Recommendations for triglyceride measurements. Clin. Chem. Clin., 41: 1421-1426.
23. Tandon, S., 2005. Phytochemicals and cardiovascular health. Curr. R and D High, 28: 18-22.
24. Tripathi, S.N., 1975. Effects of a ketosteroid of Commiphora mukul on hypercholesterolemia and hyperlipidemia induced by neomercazole and cholesterol mixture in chicks. Indian J. Exp. Biol., 13: 15-18.
25. Urizar, N.L., A.B. Liverman, D.T. Dodds, F.V. Silva, P. Ordenlich, I. Yan, F.J. Gonzalez, R.A. Heyman, D.J. Mangelsdorf and D.D. Moore, 2002. A natural product that lowers cholesterol as antagonist ligand for FXR. Sci., 296: 1703-1706.
26. Verna, S.K. and A. Bordia, 1988. Effects of Commiphora mukul resin (gum guggul) in patients of hyperlipidemia with special reference to HDL. Ind. J. Med. Res., 87: 356-360.
27. Vogel, J.H.K., S.F. Bollings, R.B. Costello, E.M. Guarneri, M.W. Krucoff, J.C. Longhurst, B. Olshansky, K.R. Pelletier, C.M. Tracy and R.A. Vogel, 2005. Integrating complementary medicine into cardiovascular medicine. J. Am. Coll. Cardiol., 46: 184-221.
28. Wang, X., J. Greilberger, G. Ledinski, G. Kager, B. Paigen and G. Jurgens, 2004. The hypolipidemic natural product, Commiphora mukul and its component guggulsterone inhibit oxidative modification of LDL. Atherosclerosis, 172: 239-246.