Gene therapy of uterine leiomyoma: Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir treatment inhibits growth of human and rat leiomyoma cells in vitro and in a nude mouse model

Gynecologic and Obstetric Investigation

Volumn 63, Issue 2, 2007, Pages 61-70

  Salama, S A ^a   Kamel, M ^a   Christman, G ^c   Wang, H Q ^b   Fouad, H M ^a   Al Hendy, A ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Adenovirus thymidine kinase; Gene therapy; Leiomyomas

Indexed keywords

ADENOVIRUS VECTOR; GANCICLOVIR; THYMIDINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GENE THERAPY; CELL COUNT; CELL KILLING; COCULTURE; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; GENE TRANSFER; GENETIC TRANSFECTION; GROWTH INHIBITION; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; NUDE MOUSE; PLAQUE FORMING CELL; PRIORITY JOURNAL; RAT; TUMOR CELL; TUMOR MODEL; UTERUS MYOMA; VIRAL GENE THERAPY;

ADENOVIRIDAE; ANIMALS; ANTIVIRAL AGENTS; BYSTANDER EFFECT; CELL LINE, TUMOR; COMBINED MODALITY THERAPY; CONNEXIN 43; FEMALE; GANCICLOVIR; GENE THERAPY; HUMANS; LEIOMYOMA; MICE; MICE, NUDE; RATS; RECOMBINANT PROTEINS; SIMPLEXVIRUS; THYMIDINE KINASE; TRANSFECTION; UTERINE NEOPLASMS;

EID: 33846988645     PISSN: 03787346     EISSN: None     Source Type: Journal    
DOI: 10.1159/000095627     Document Type: Article

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