-
2
-
-
0028123444
-
CD28-mediated costimulation of interleukin 2 (IL-2) production plays a critical role in T cell priming for IL-4 and interferon gamma production
-
Seder RA, Germain RN, Linsley PS, Paul WE. CD28-mediated costimulation of interleukin 2 (IL-2) production plays a critical role in T cell priming for IL-4 and interferon gamma production. J Exp Med 1994; 179: 299.
-
(1994)
J Exp Med
, vol.179
, pp. 299
-
-
Seder, R.A.1
Germain, R.N.2
Linsley, P.S.3
Paul, W.E.4
-
3
-
-
0029163387
-
CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL
-
Boise LH, Minn AJ, Noel PJ, et al. CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. Immunity 1995; 3: 87.
-
(1995)
Immunity
, vol.3
, pp. 87
-
-
Boise, L.H.1
Minn, A.J.2
Noel, P.J.3
-
4
-
-
85047693292
-
CD28 ligation induces transplantation tolerance by IFN-gamma-dependent depletion of T cells that recognize alloantigens
-
Yu XZ, Albert MH, Martin PJ, Anasetti C. CD28 ligation induces transplantation tolerance by IFN-gamma-dependent depletion of T cells that recognize alloantigens. J Clin Invest 2004; 113: 1624.
-
(2004)
J Clin Invest
, vol.113
, pp. 1624
-
-
Yu, X.Z.1
Albert, M.H.2
Martin, P.J.3
Anasetti, C.4
-
5
-
-
0026778697
-
Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule
-
Linsley PS, Wallace PM, Johnson J, et al. Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule. Science 1992; 257: 792.
-
(1992)
Science
, vol.257
, pp. 792
-
-
Linsley, P.S.1
Wallace, P.M.2
Johnson, J.3
-
6
-
-
0035059417
-
Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation
-
Salomon B, Bluestone JA. Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation. Annu Rev Immunol 2001; 19: 225.
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 225
-
-
Salomon, B.1
Bluestone, J.A.2
-
7
-
-
0038156291
-
Selective blockade of CD28 and not CTLA-4 with a single-chain Fv-alpha1-antitrypsin fusion antibody
-
Vanhove B, Laflamme G, Coulon F, et al. Selective blockade of CD28 and not CTLA-4 with a single-chain Fv-alpha1-antitrypsin fusion antibody. Blood 2003; 102: 564.
-
(2003)
Blood
, vol.102
, pp. 564
-
-
Vanhove, B.1
Laflamme, G.2
Coulon, F.3
-
8
-
-
33644686064
-
Anti-CD28 antibody-induced kidney allograft tolerance related to tryptophan degradation and TCR class II B7 regulatory cells
-
Haspot F, Seveno C, Dugast AS, et al. Anti-CD28 antibody-induced kidney allograft tolerance related to tryptophan degradation and TCR class II B7 regulatory cells. Am J Transplant 2005; 5: 2339.
-
(2005)
Am J Transplant
, vol.5
, pp. 2339
-
-
Haspot, F.1
Seveno, C.2
Dugast, A.S.3
-
9
-
-
0028819315
-
CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL
-
Lanier LL, O'Fallon S, Somoza C, et al. CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL. J Immunol 1995; 154: 97.
-
(1995)
J Immunol
, vol.154
, pp. 97
-
-
Lanier, L.L.1
O'Fallon, S.2
Somoza, C.3
-
10
-
-
1642485638
-
IL-11 protects human microvascular endothelium from alloinjury in vivo by induction of surviving expression
-
Kirkiles-Smith NC, Mahboubi K, Plescia J, et al. IL-11 protects human microvascular endothelium from alloinjury in vivo by induction of surviving expression. J Immunol 2004; 172: 1391.
-
(2004)
J Immunol
, vol.172
, pp. 1391
-
-
Kirkiles-Smith, N.C.1
Mahboubi, K.2
Plescia, J.3
-
11
-
-
26844498650
-
Memory T cells and their costimulators in human allograft injury
-
Shiao SL, McNiff JM, Pober JS. Memory T cells and their costimulators in human allograft injury. J Immunol 2005; 175: 4886.
-
(2005)
J Immunol
, vol.175
, pp. 4886
-
-
Shiao, S.L.1
McNiff, J.M.2
Pober, J.S.3
-
13
-
-
0034192096
-
Cytoprotection of human umbilical vein endothelial cells against apoptosis and CTL-mediated lysis provided by caspase-resistant Bcl-2 without alterations in growth or activation responses
-
Zheng L, Dengler TJ, Kluger MS, et al. Cytoprotection of human umbilical vein endothelial cells against apoptosis and CTL-mediated lysis provided by caspase-resistant Bcl-2 without alterations in growth or activation responses. J Immunol 2000; 164: 4665.
-
(2000)
J Immunol
, vol.164
, pp. 4665
-
-
Zheng, L.1
Dengler, T.J.2
Kluger, M.S.3
-
14
-
-
0028607443
-
Human T-cell-mediated destruction of allogeneic dermal microvessels in a severe combined immunodeficient mouse
-
Murray AG, Petzelbauer P, Hughes CC, Costa J, Askenase P, Pober JS. Human T-cell-mediated destruction of allogeneic dermal microvessels in a severe combined immunodeficient mouse. Proc Natl Acad Sci U S A 1994; 91: 9146.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 9146
-
-
Murray, A.G.1
Petzelbauer, P.2
Hughes, C.C.3
Costa, J.4
Askenase, P.5
Pober, J.S.6
-
15
-
-
0030746377
-
Blockade of CD2-LFA-3 interactions protects human skin allografts in immunodeficient mouse/human chimeras
-
Sultan P, Schechner JS, McNiff JM, et al. Blockade of CD2-LFA-3 interactions protects human skin allografts in immunodeficient mouse/human chimeras. Nat Biotechnol 1997; 15: 759.
-
(1997)
Nat Biotechnol
, vol.15
, pp. 759
-
-
Sultan, P.1
Schechner, J.S.2
McNiff, J.M.3
-
16
-
-
2942716900
-
Interferon alpha but not interleukin 12 activates STAT4 signaling in human vascular endothelial cells
-
Torpey N, Maher SE, Bothwell AL, Pober JS. Interferon alpha but not interleukin 12 activates STAT4 signaling in human vascular endothelial cells. J Biol Chem 2004; 279: 26789.
-
(2004)
J Biol Chem
, vol.279
, pp. 26789
-
-
Torpey, N.1
Maher, S.E.2
Bothwell, A.L.3
Pober, J.S.4
-
17
-
-
0342626639
-
Impaired antigen presentation by human monocytes during endotoxin tolerance
-
Wolk K, Docke WD, von Baehr V, Volk HD, Sabat R. Impaired antigen presentation by human monocytes during endotoxin tolerance. Blood 2000; 96: 218.
-
(2000)
Blood
, vol.96
, pp. 218
-
-
Wolk, K.1
Docke, W.D.2
von Baehr, V.3
Volk, H.D.4
Sabat, R.5
-
18
-
-
0028289244
-
Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha
-
Sallusto F, Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J Exp Med 1994; 179: 1109.
-
(1994)
J Exp Med
, vol.179
, pp. 1109
-
-
Sallusto, F.1
Lanzavecchia, A.2
-
19
-
-
0027451441
-
Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion
-
Lin H, Bolling SF, Linsley PS, et al. Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion. J Exp Med 1993; 178: 1801.
-
(1993)
J Exp Med
, vol.178
, pp. 1801
-
-
Lin, H.1
Bolling, S.F.2
Linsley, P.S.3
-
20
-
-
0032490629
-
B7-1 engagement of cytotoxic T lymphocyte antigen 4 inhibits T cell activation in the absence of CD28
-
Fallarino F, Fields PE, Gajewski TF. B7-1 engagement of cytotoxic T lymphocyte antigen 4 inhibits T cell activation in the absence of CD28. J Exp Med 1998; 188: 205.
-
(1998)
J Exp Med
, vol.188
, pp. 205
-
-
Fallarino, F.1
Fields, P.E.2
Gajewski, T.F.3
-
21
-
-
0036467522
-
CD25CD4regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses
-
Kingsley CI, Karim M, Bushell AR, Wood KJ. CD25CD4regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses. J Immunol 2002; 168: 1080.
-
(2002)
J Immunol
, vol.168
, pp. 1080
-
-
Kingsley, C.I.1
Karim, M.2
Bushell, A.R.3
Wood, K.J.4
-
22
-
-
0033179230
-
Blockade of CD28 during in vitro activation of encephalitogenic T cells or after disease onset ameliorates experimental autoimmune encephalomyelitis
-
Perrin PJ, June CH, Maldonado JH, Ratts RB, Racke MK. Blockade of CD28 during in vitro activation of encephalitogenic T cells or after disease onset ameliorates experimental autoimmune encephalomyelitis. J Immunol 1999; 163: 1704.
-
(1999)
J Immunol
, vol.163
, pp. 1704
-
-
Perrin, P.J.1
June, C.H.2
Maldonado, J.H.3
Ratts, R.B.4
Racke, M.K.5
-
23
-
-
0034327175
-
Blockade of costimulation through B7/CD28 inhibits experimental autoimmune uveoretinitis, but does not induce long-term tolerance
-
Silver PB, Hathcock KS, Chan CC, Wiggert B, Caspi RR. Blockade of costimulation through B7/CD28 inhibits experimental autoimmune uveoretinitis, but does not induce long-term tolerance. J Immunol 2000; 165: 5041.
-
(2000)
J Immunol
, vol.165
, pp. 5041
-
-
Silver, P.B.1
Hathcock, K.S.2
Chan, C.C.3
Wiggert, B.4
Caspi, R.R.5
-
24
-
-
23744517125
-
Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis
-
Beyersdorf N, Gaupp S, Balbach K, et al. Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis. J Exp Med 2005; 202: 445.
-
(2005)
J Exp Med
, vol.202
, pp. 445
-
-
Beyersdorf, N.1
Gaupp, S.2
Balbach, K.3
-
26
-
-
0042320414
-
Memory T cells: A hurdle to immunologic tolerance
-
Lakkis FG, Sayegh MH. Memory T cells: a hurdle to immunologic tolerance. J Am Soc Nephrol 2003; 14: 2402.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 2402
-
-
Lakkis, F.G.1
Sayegh, M.H.2
-
27
-
-
0035889949
-
Role of CD28-B7 interactions in generation and maintenance of CD8 T cell memory
-
Suresh M, Whitmire JK, Harrington LE, et al. Role of CD28-B7 interactions in generation and maintenance of CD8 T cell memory. J Immunol 2001; 167: 5565.
-
(2001)
J Immunol
, vol.167
, pp. 5565
-
-
Suresh, M.1
Whitmire, J.K.2
Harrington, L.E.3
-
28
-
-
0033575775
-
Endothelial cells modify the costimulatory capacity of transmigrating leukocytes and promote CD28-mediated CD4() T cell alloactivation
-
Denton MD, Geehan CS, Alexander SI, Sayegh MH, Briscoe DM. Endothelial cells modify the costimulatory capacity of transmigrating leukocytes and promote CD28-mediated CD4() T cell alloactivation. J Exp Med 1999; 190: 555.
-
(1999)
J Exp Med
, vol.190
, pp. 555
-
-
Denton, M.D.1
Geehan, C.S.2
Alexander, S.I.3
Sayegh, M.H.4
Briscoe, D.M.5
-
29
-
-
33646379402
-
Injury to research volunteers-the clinicalresearch nightmare
-
Wood AJ, Darbyshire J. Injury to research volunteers-the clinicalresearch nightmare. N Engl J Med 2006; 354: 1869.
-
(2006)
N Engl J Med
, vol.354
, pp. 1869
-
-
Wood, A.J.1
Darbyshire, J.2
-
30
-
-
33749865231
-
-
Available at:, Published online 5 April
-
Hopkin M. Drug to blame for clinical-trial disaster? Available at: www.nature.com/news/2006/060403/full/060403-8.html. Published online 5 April 2006.
-
(2006)
Drug to blame for clinical-trial disaster
-
-
Hopkin, M.1
|