ABCA1, ABCG1 and SR-BI: Hormonal regulation in primary rat hepatocytes and human cell lines

BMC Molecular Biology

Volumn 8, Issue , 2007, Pages

  Sporstøl, Marita ^a   Mousavi, Seyed Ali ^a   Eskild, Winnie ^a   Roos, Norbert ^a   Berg, Trond ^a  

^a UNIVERSITY OF OSLO   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER A1; ABC TRANSPORTER G1; DEXAMETHASONE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; INSULIN; MESSENGER RNA; MIFEPRISTONE; SCAVENGER RECEPTOR BI; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOHYDRATE METABOLISM; CELL STRAIN HEPG2; CELLULAR DISTRIBUTION; CHOLESTEROL METABOLISM; CONTROLLED STUDY; GENE CONTROL; HORMONAL REGULATION; HORMONE ACTION; HUMAN; HUMAN CELL; LIVER CELL; MACROPHAGE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELLS, CULTURED; CHOLESTEROL; DEXAMETHASONE; HEPATOCYTES; HUMANS; INSULIN; MACROPHAGES; RATS; RATS, WISTAR; RECEPTORS, GLUCOCORTICOID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SCAVENGER RECEPTORS, CLASS B;

RATTUS;

EID: 33846968795     PISSN: None     EISSN: 14712199     Source Type: Journal    
DOI: 10.1186/1471-2199-8-5     Document Type: Article

References (38)

1. Glomset JA The plasma lecithins:cHolesterol acyltransferase reaction J Lipid Res 1968 9 2 155-167 4868699
2. Acton S Rigotti A Landschulz KT Xu S Hobbs HH Krieger M Identification of scavenger receptor SR-BI as a high density lipoprotein receptor Science 1996 271 5248 518-520 10.1126/science.271.5248.518 8560269
3. Landschulz KT Pathak RK Rigotti A Krieger M Hobbs HH Regulation of scavenger receptor, class B, type I, a high density lipoprotein receptor, in liver and steroidogenic tissues of the rat J Clin Invest 1996 98 4 984-995 507514 8770871
4. Chinetti G Gbaguidi FG Griglio S Mallat Z Antonucci M Poulain P Chapman J Fruchart JC Tedgui A Najib-Fruchart J Staels B CLA-1/SR-BI is expressed in atherosclerotic lesion macrophages and regulated by activators of peroxisome proliferator-activated receptors Circulation 2000 101 20 2411-2417 10821819
5. Fluiter K van der Westhuijzen DR van Berkel TJ In vivo regulation of scavenger receptor BI and the selective uptake of high density lipoprotein cholesteryl esters in rat liver parenchymal and Kupffer cells J Biol Chem 1998 273 14 8434-8438 10.1074/jbc.273.14.8434 9525955
6. Bortnick AE Rothblat GH Stoudt G Hoppe KL Royer LJ McNeish J Francone OL The correlation of ATP-binding cassette 1 mRNA levels with cholesterol efflux from various cell lines J Biol Chem 2000 275 37 28634-28640 10.1074/jbc.M003407200 10893411
7. Brooks-Wilson A Marcil M Clee SM Zhang LH Roomp K van Dam M Yu L Brewer C Collins JA Molhuizen HO Loubser O Ouelette BF Fichter K Ashbourne-Excoffon KJ Sensen CW Scherer S Mott S Denis M Martindale D Frohlich J Morgan K Koop B Pimstone S Kastelein JJ Genest J Jr. Hayden MR Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency Nat Genet 1999 22 4 336-345 10.1038/11905 10431236
8. Lawn RM Wade DP Garvin MR Wang X Schwartz K Porter JG Seilhamer JJ Vaughan AM Oram JF The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway J Clin Invest 1999 104 8 R25-31 481052 10525055
9. Neufeld EB Demosky SJ Jr. Stonik JA Combs C Remaley AT Duverger N Santamarina-Fojo S Brewer HB Jr. The ABCA1 transporter functions on the basolateral surface of hepatocytes Biochem Biophys Res Commun 2002 297 4 974-979 10.1016/S0006-291X(02)02274-X 12359250
10. Wang N Silver DL Thiele C Tall AR ATP-binding cassette transporter A1 (ABCA1) functions as a cholesterol efflux regulatory protein J Biol Chem 2001 276 26 23742-23747 10.1074/jbc.M102348200 11309399
11. Orso E Broccardo C Kaminski WE Bottcher A Liebisch G Drobnik W Gotz A Chambenoit O Diederich W Langmann T Spruss T Luciani MF Rothe G Lackner KJ Chimini G Schmitz G Transport of lipids from golgi to plasma membrane is defective in tangier disease patients and Abc1-deficient mice Nat Genet 2000 24 2 192-196 10.1038/72869 10655069
12. Remaley AT Rust S Rosier M Knapper C Naudin L Broccardo C Peterson KM Koch C Arnould I Prades C Duverger N Funke H Assman G Dinger M Dean M Chimini G Santamarina-Fojo S Fredrickson DS Denefle P Brewer HB Jr. Human ATP-binding cassette transporter 1 (ABC1): Genomic organization and identification of the genetic defect in the original Tangier disease kindred Proc Natl Acad Sci U S A 1999 96 22 12685-12690 23050 10535983 10.1073/pnas.96.22.12685
13. Klucken J Buchler C Orso E Kaminski WE Porsch-Ozcurumez M Liebisch G Kapinsky M Diederich W Drobnik W Dean M Allikmets R Schmitz G ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport Proc Natl Acad Sci U S A 2000 97 2 817-822 15414 10639163 10.1073/pnas.97.2.817
14. Wang N Lan D Chen W Matsuura F Tall AR ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins Proc Natl Acad Sci U S A 2004 101 26 9774-9779 470750 15210959 10.1073/pnas.0403506101
15. Kino T Chrousos GP Glucocorticoid and mineralocorticoid resistance/ hypersensitivity syndromes J Endocrinol 2001 169 3 437-445 10.1677/ joe.0.1690437 11375113
16. Beato M Sanchez-Pacheco A Interaction of steroid hormone receptors with the transcription initiation complex Endocr Rev 1996 17 6 587-609 10.1210/er.17.6.587 8969970
17. Spitz IM Bardin CW Mifepristone (RU 486) - a modulator of progestin and glucocorticoid action N Engl J Med 1993 329 6 404-412 10.1056/ NEJM199308053290607 8326975
18. Hylemon PB Gurley EC Stravitz RT Litz JS Pandak WM Chiang JY Vlahcevic ZR Hormonal regulation of cholesterol 7 alpha-hydroxylase mRNA levels and transcriptional activity in primary rat hepatocyte cultures J Biol Chem 1992 267 24 16866-16871 1512229
19. Twisk J Hoekman MF Lehmann EM Meijer P Mager WH Princen HM Insulin suppresses bile acid synthesis in cultured rat hepatocytes by down-regulation of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase gene transcription Hepatology 1995 21 2 501-510 10.1016/ 0270-9139(95)90113-2 7843724
20. Trawick JD Lewis KD Dueland S Moore GL Simon FR Davis RA Rat hepatoma L35 cells, a liver-differentiated cell line, display resistance to bile acid repression of cholesterol 7 alpha-hydroxylase J Lipid Res 1996 37 3 588-598 8728321
21. Trawick JD Wang SL Bell D Davis RA Transcriptional induction of cholesterol 7alpha-hydroxylase by dexamethasone in L35 hepatoma cells requires sulfhydryl reducing agents J Biol Chem 1997 272 5 3099-3102 10.1074/jbc.272.5.3099 9006961
22. Elshourbagy NA Boguski MS Liao WS Jefferson LS Gordon JI Taylor JM Expression of rat apolipoprotein A-IV and A-I genes: MRNA induction during development and in response to glucocorticoids and insulin Proc Natl Acad Sci U S A 1985 82 23 8242-8246 391479 3934672 10.1073/ pnas.82.23.8242
23. Lin RC Effects of hormones on apolipoprotein secretion in cultured rat hepatocytes Metabolism 1988 37 8 745-751 10.1016/0026-0495(88)90009-1 3136298
24. Masumoto A Koga S Uchida E Ibayashi H Effects of insulin, dexamethasone and glucagon on the production of apolipoprotein A-I in cultured rat hepatocytes Atherosclerosis 1988 70 3 217-223 10.1016/ 0021-9150(88)90172-4 3130065
25. Saladin R Vu-Dac N Fruchart JC Auwerx J Staels B Transcriptional induction of rat liver apolipoprotein A-I gene expression by glucocorticoids requires the glucocorticoid receptor and a labile cell-specific protein Eur J Biochem 1996 239 2 451-459 10.1111/ j.1432-1033.1996.0451u.x 8706754
26. Staels B van Tol A Chan L Verhoeven G Auwerx J Variable effects of different corticosteroids on plasma lipids, apolipoproteins, and hepatic apolipoprotein mRNA levels in rats Arterioscler Thromb 1991 11 3 760-769 1903065
27. Taylor AH Raymond J Dionne JM Romney J Chan J Lawless DE Wanke IE Wong NC Glucocorticoid increases rat apolipoprotein A-I promoter activity J Lipid Res 1996 37 10 2232-2243 8906599
28. Ayaori M Sawada S Yonemura A Iwamoto N Ogura M Tanaka N Nakaya K Kusuhara M Nakamura H Ohsuzu F Glucocorticoid receptor regulates ATP-binding cassette transporter-A1 expression and apolipoprotein-mediated cholesterol efflux from macrophages Arterioscler Thromb Vasc Biol 2006 26 1 163-168 10.1161/01.ATV.0000193513.29074.52 16254209
29. Malerod L Sporstol M Juvet LK Mousavi A Gjoen T Berg T Hepatic scavenger receptor class B, type I is stimulated by peroxisome proliferator-activated receptor gamma and hepatocyte nuclear factor 4alpha Biochem Biophys Res Commun 2003 305 3 557-565 10.1016/ S0006-291X(03)00819-2 12763030
30. Malerod L Sporstol M Juvet LK Mousavi SA Gjoen T Berg T Roos N Eskild W Bile acids reduce SR-BI expression in hepatocytes by a pathway involving FXR/RXR, SHP, and LRH-1 Biochem Biophys Res Commun 2005 336 4 1096-1105 10.1016/j.bbrc.2005.08.237 16168958
31. Sporstol M Tapia G Malerod L Mousavi SA Berg T Pregnane X receptor-agonists down-regulate hepatic ATP-binding cassette transporter A1 and scavenger receptor class B type I Biochem Biophys Res Commun 2005 331 4 1533-1541 10.1016/j.bbrc.2005.04.071 15883047
32. Schwartz CC Halloran LG Vlahcevic ZR Gregory DH Swell L Preferential utilization of free cholesterol from high-density lipoproteins for biliary cholesterol secretion in man Science 1978 200 4337 62-64 10.1126/ science.204996 204996
33. Mayer D The circadian rhythm of synthesis and catabolism of cholesterol Arch Toxicol 1976 36 3-4 267-276 10.1007/BF00340534 1036900
34. Subbiah MT Yunker RL Cholesterol 7 alpha-hydroxylase of rat liver: An insulin sensitive enzyme Biochem Biophys Res Commun 1984 124 3 896-902 10.1016/0006-291X(84)91042-8 6391484
35. Bocharov AV Huang W Vishniakova TG Zaitseva EV Frolova EG Rampal P Bertolotti R Glucocorticoids upregulate high-affinity, high-density lipoprotein binding sites in rat hepatocytes Metabolism 1995 44 6 730-738 10.1016/0026-0495(95)90185-X 7783657
36. Malerod L Juvet K Gjoen T Berg T The expression of scavenger receptor class B, type I (SR-BI) and caveolin-1 in parenchymal and nonparenchymal liver cells Cell Tissue Res 2002 307 2 173-180 10.1007/s00441-001-0476-9 11845324
37. Fronsdal K Engedal N Saatcioglu F Efficient DNA-mediated gene transfer into prostate cancer cell line LNCaP Prostate 2000 43 2 111-117 10.1002/ (SICI)1097-0045(20000501)43:2<111::AID-PROS5>3.0.CO;2-4 10754526
38. Primer3 http://frodo.wi.mit.edu/cgi-bin/primer3/primer3_www.cgi