Orexins: Looking forward to sleep, back at addiction

Nature Medicine

Volumn 13, Issue 2, 2007, Pages 126-128

  Scammell, Thomas E ^a   Saper, Clifford B ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR STIMULATING AGENT; ACT 078573; ANTIHISTAMINIC AGENT; BENZODIAZEPINE; HORMONE RECEPTOR STIMULATING AGENT; OPIATE ANTAGONIST; OREXIN; OREXIN A; OREXIN B; UNCLASSIFIED DRUG; ZOLPIDEM;

ADDICTION; ALERTNESS; AROUSAL; BEHAVIOR; BRAIN REGION; CATAPLEXY; DRUG EFFICACY; DRUG MECHANISM; HUMAN; HYPOTHALAMUS; INSOMNIA; NARCOLEPSY; NERVE CELL; NONHUMAN; OBESITY; PARALYSIS; PRIORITY JOURNAL; REM SLEEP; SHORT SURVEY; SLEEP DISORDER; SOMNOLENCE; SUBSTANCE ABUSE; VIVID DREAM; WAKEFULNESS;

HUMANS; HYPOTHALAMUS, POSTERIOR; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; NEUROPEPTIDES; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROPEPTIDE; SIGNAL TRANSDUCTION; SLEEP DISORDERS;

EID: 33846956089     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm0207-126     Document Type: Short Survey

References (15)

1. Siegel, J.M. Annu. Rev. Psychol. 55, 125148 (2004).
2. Brisbare-Roch, C. et al. Nat. Med. 13, 150-155 (2007).
3. Peyron, C. et al. Nat. Med. 6, 991-997 (2000).
4. Thannickal, T.C. et al. Neuron 27, 469-474 (2000).
5. Crocker, A. et al. Neurology 65, 1184-1188 (2005).
6. Lee, M.G., Hassani, O.K. & Jones, B.E. J. Neurosci. 25, 6716-6720 (2005).
7. Mileykovskiy, B.Y., Kiyashchenko, L.I. & Siegel, J.M. Neuron 46, 787-798 (2005).
8. Estabrooke, I.V. et al. J. Neurosci. 21, 1656-1662 (2001).
9. Chemelli, R.M. et al. Cell 98, 437-451 (1999).
10. Beuckmann, C.T. et al. J. Neurosci. 24, 4469-4477 (2004).
11. Lin, L. et al. Cell 98, 365-376 (1999).
12. Mochizuki, T. et al. J. Neurosci. 24, 6291-6300 (2004).
13. Harris, G.C., Wimmer, M. & Aston-Jones, G. Nature 437, 556-559 (2005).
14. Hara, J., Yanagisawa, M. & Sakurai, T. Neurosci. Lett. 380, 239-242 (2005).
15. Narita, M. et al. J. Neurosci. 26, 398-405 (2006).