Effects of ectodomain sequences between HR1 and HR2 of F1 protein on the specific membrane fusion in paramyxoviruses

Intervirology

Volumn 50, Issue 2, 2007, Pages 115-122

  Ren, Guijie ^a   Wang, Zhiyu ^a,b   Hu, Xiaoyan ^a  

^a SHANDONG UNIVERSITY   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

Author keywords

Ectodomain sequences; Fusion protein; Paramyxovirus; Specific membrane fusion

Indexed keywords

F1 PROTEIN; HEMAGGLUTININ; HYBRID PROTEIN; MUTANT PROTEIN; SIALIDASE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; CELL STRAIN BHK; CELL SURFACE; CONTROLLED STUDY; DNA SEQUENCE; EUKARYOTIC CELL; FLUORESCENCE ACTIVATED CELL SORTER; GENETIC RECOMBINATION; GIEMSA STAIN; MEMBRANE FUSION; NEWCASTLE DISEASE PARAMYXOVIRUS; NONHUMAN; PARAINFLUENZA VIRUS; PARAMYXOVIRUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; REPORTER GENE; SITE DIRECTED MUTAGENESIS;

BETA-GALACTOSIDASE; FLOW CYTOMETRY; GENES, REPORTER; HISTOCYTOCHEMISTRY; HN PROTEIN; IMMUNOHISTOCHEMISTRY; MICROSCOPY; MUTAGENESIS, SITE-DIRECTED; NEWCASTLE DISEASE VIRUS; PARAMYXOVIRIDAE; RECOMBINATION, GENETIC; RESPIROVIRUS; VIRAL FUSION PROTEINS; VIRAL PROTEINS; VIRUS INTERNALIZATION;

NEWCASTLE DISEASE VIRUS; PARAINFLUENZA VIRUS; PARAMYXOVIRIDAE;

EID: 33846949693     PISSN: 03005526     EISSN: None     Source Type: Journal    
DOI: 10.1159/000098237     Document Type: Article

References (24)

1. Wild T F, Malvoisin E, Buckland R: Measles virus: Both the hemagglutinin and fusion glycoproteins are required for fusion. J Gen Virol 1991;72:439-442.
2. Hu X, Ray R, Compans RW: Functional interaction between the fusion protein and hemagglutinin-neuraminidase of human parainfluenza viruses. J Virol 1992;66:1528-1534.
3. Deng R, Wang Z, Mahon P J, Marinello M, Mirza A, Iorio RM: Mutations in the Newcastle disease virus hemagglutinin-neuraminidase protein that interfere with its ability to interact with the homologous F protein in the promotion of fusion. Virology 1999;253:43-54.
4. Chen L, Colman PM, Cosgrove LJ, Lawrence MC, Lawrence LJ, Tulloch PA, Gorman JJ: Cloning, expression and crystallization of the fusion protein of Newcastle disease virus. Virology 2001;290:290-299.
5. Chen L, Gorman JJ, McKimm-Breschkin J, Lawrence LJ, Tulloch PA, Smith BJ, Colman PM, Lawrence MC: The structure of the fusion glycoprotein of Newcastle disease virus suggests a novel paradigm for the molecular mechanism of membrane fusion. Structure (Camb) 2001;9:255-266.
6. Gravel KA, Morrison TG: Interacting domains of the HN and F proteins of Newcastle disease virus. J Virol 2003;77:11040-11049.
7. Sergel TA, McGinnes LW, Morrison TG: Mutations in the fusion peptide and adjacent heptad repeat inhibit folding or activity of the Newcastle disease virus fusion protein. J Virol 2001;75:7934-7943.
8. Morrison TG: Structure and function of a paramyxovirus fusion protein. Biochim Biophys Acta 2003;1614:73-84.
9. Sergel-German T, McQuain C, Morrison T: Mutations in the fusion peptide and heptad repeat regions of the Newcastle disease virus fusion protein block fusion. J Virol 1994;68:7654-7658.
10. Lawrence MC, Borg NA, Streltsov VA, Pilling PA, Epa VC, Varghese JN, McKimm-Breschkin JL, Colman PM: Structure of the haemagglutinin-neuraminidase from human parainfluenza virus type III. J Mol Biol 2004;335:1343-1357.
11. Ferreira L, Munoz-Barroso I, Marcos F, Shnyrov V L, Villar E: Sialidase, receptor-binding and fusion-promotion activities of Newcastle disease virus haemagglutinin-neuraminidase glycoprotein: a mutational and kinetic study. J Gen Virol 2004;85:1981-1988.
12. Wang Z, Mirza AM, Li J, Mahon PJ, Iorio RM: An oligosaccharide at the C-terminus of the F-specific domain in the stalk of the human parainfluenza virus 3 hemagglutinin-neuraminidase modulates fusion. Virus Res 2004;99:177-185.
13. Wang Z: Preliminary identification of an active domain on fusion protein of paramyxoviruses. Chin J Microbiol Immunol 2002;20:289-292.
14. Ren G, Wang Z, Wang G, Song Y, Yao P, Xu H, Wen H, Zhang W: Effects of heptad repeat regions of F protein on the specific membrane fusion in paramyxoviruses. Intervirology 2006;49:299-306.
15. Fuerst TR, Niles EG, Studier FW, Moss B: Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase. Proc Natl Acad Sci USA 1986;83:8122-8126.
16. Dieffenbach CW, Dveksler GS: PCR Primer: A Laboratory Manual. Cold Spring Harbor, Cold Spring Harbor Laboratory Press, 1995, pp 421-425.
17. Mirza AM, Deng R, Iorio RM: Site-directed mutagenesis of a conserved hexapeptide in the paramyxovirus hemagglutinin-neuraminidase glycoprotein: effects on antigenic structure and function. J Virol 1994;68:5093-5099.
18. Wang Z, Yu X: Quantitative analysis of cell fusion caused by glycoprotein of paramyxoviruses with reporter gene method. Chin J Exp Clin Virol 2001;15:179-181.
19. Deng R, Wang Z, Mirza AM, Iorio RM: Localization of a domain on the paramyxovirus attachment protein required for the promotion of cellular fusion by its homologous fusion protein spike. Virology 1995;209:457-469.
20. Huang Z, Panda A, Elankumaran S, Govindarajan D, Rockemann DD, Samal S K: The hemagglutinin-neuraminidase protein of Newcastle disease virus determines tropism and virulence. J Virol 2004;78:4176-4184.
21. McGinnes LW, Gravel K, Morrison TG: Newcastle disease virus HN protein alters the conformation of the F protein at cell surfaces. J Virol 2002;76:12622-12633.
22. Porotto M, Murrell M, Greengard O, Moscona A: Triggering of human parainfluenza virus 3 fusion protein (F) by the hemagglutinin-neuraminidase (HN) protein: An HN mutation diminishes the rate of F activation and fusion. J Virol 2003;77:3647-3654.
23. Porotto M, Murrell M, Greengard O, Doctor L, Moscona A: Influence of the human parainfluenza virus 3 attachment protein's neuraminidase activity on its capacity to activate the fusion protein. J Virol 2005;79:2383-2392.
24. Lamb RA, Paterson RG, Jardetzky TS: Paramyxovirus membrane fusion: lessons from the F and HN atomic structures. Virology 2006;344:30-37.