Primary and secondary immune responses of mucosal and peripheral lymphocytes during Chlamydia trachomatis infection

FEMS Immunology and Medical Microbiology

Volumn 49, Issue 2, 2007, Pages 280-287

  Vats, Vikas ^a   Agrawal, Tanvi ^a   Salhan, Sudha ^b   Mittal, Aruna ^a,b  

^a SAFDARJUNG HOSPITAL CAMPUS   (India)

^b SAFDARJUNG HOSPITAL   (India)

Author keywords

Chlamydia trachomatis; Cytokines; MOMP antigen; Proliferative response

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL PROTEIN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 6; OUTER MEMBRANE PROTEIN;

ADULT; ARTICLE; CELL PROLIFERATION; CHLAMYDIA TRACHOMATIS; CHLAMYDIASIS; CONTROLLED STUDY; FEMALE; FEMALE GENITAL SYSTEM; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LYMPHOCYTE; MAJOR CLINICAL STUDY; PERIPHERAL BLOOD MONONUCLEAR CELL; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN SECRETION; TH2 CELL;

BACTERIAL OUTER MEMBRANE PROTEINS; CELL PROLIFERATION; CERVIX UTERI; CHLAMYDIA INFECTIONS; CHLAMYDIA TRACHOMATIS; FEMALE; HUMANS; IMMUNITY, MUCOSAL; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; LYMPHOCYTES;

EID: 33846944683     PISSN: 09288244     EISSN: 1574695X     Source Type: Journal    
DOI: 10.1111/j.1574-695X.2006.00196.x     Document Type: Article

References (29)

1. Bailey RL, Holand MJ, Whittle HC & Mabey DC (1995) Subjects recovering from human ocular chlamydial infection have enhance lymphoproliferative responses to chlamydial antigens compared with those of persistently diseased controls. Infect Immunol 63: 389-392.
2. Brunham RC, Kimani Bwayo J, Maitha G, Maclean I, Yang C, Shen C, Roman S, Nagelkerke NJ, Cheang M & Plummer FA (1996) The epidemiology of Chlamydia trachomatis within a sexually transmitted disease core group. J Infect Dis 173: 950-956.
3. Buzoni-Gatel D, Guilloteau L, Bernard F, Bernard S, Chardes T & Rocca A (1992) Protection against Chlamydia psittaci in mice conferred by Lyt-2 T cells. Immunology 77: 284-288.
4. Cohen CR, Sinei SS, Bukusi EA, Bwayo JJ, Holmes KK & Brunham RC (2000) Human leukocyte antigen class II DQ alleles associated with Chlamydia trachomatis tubal infertility. Obstet Gynecol 95: 72-77.
5. Cohen CR, Koochesfahani KM, Meier AS, Shen C, Karunakaran K, Ondondo B, Kinyari T, Mugo NR, Ngutj R & Brunham RC (2005) Immunoepidemiological profile of Chlamydia trachomatis infection: importance of heat shock protein 60 and interferon-gamma. J Infect Dis 192: 591-599.
6. Conti P, Kampuraj D, Kandere K, Di Gioacchino M, Barbacane RC, Castellani ML, Felaco M, Boucher W, Letourneau R & Theoharides TC (2003) IL-10, an inflammatory/inhibitory cytokine but not always. Immunology Lett 86: 123-129.
7. Darville T, O'Neill JM, Andrews CW Jr, Nagarajan UM, Stahl L & Ojcius DM (2003) Toll like receptor-2, but not Toll like receptor-4, is essential for development of oviduct pathology in chlamydial genital tract infection. J Immunol 171: 6187-6197.
8. Grayston JT & Wang S (1975) New knowledge of Chlamydiae and the disease they cause. J Infect Dis 132: 87-105.
9. Hernandez-Pando R & Rook GAW (1994) The role of TNF-alpha in T-cell-mediated inflammation depends on the Th1/Th2 cytokine balance. Immunology 82: 591-595.
10. Holland MJ, Bailey RL, Hayes LJ, Whittle HC & Mabey DCW (1993) Conjunctival scarring in trachoma is associated with depressed cell mediated immune responses to Chlamydia antigens. J Infect Dis 168: 1528-1531.
11. Holland MJ, Bailey RL, Conway DJ, Holland MJ, Bailey RL, Conway DJ, Culley F, Miranpuri G, Byrne GI, Whittle HC & Mabey DC (1996) T helper type-1 (Th1)/Th2 profiles of peripheral blood mononuclear cells (PBMC); responses to antigens of Chlamydia trachomatis in subjects with severe trachomatous scarring. Clin Exp Immunol 105: 429-435.
12. + T cells in antichlamydial immunity defined by Chlamydia-specific T-lymphocyte clones. Infect Immunol 62: 5195-5197.
13. Igietseme JU, Uriri IM, Kumar SN, Ananaba GA, Ojior OO, Momodu IA, Candal DH & Black CM (1998) Route of infection that induces a high intensity of gamma interferon-secreting T cells in the genital tract produces optimal protection against Chlamydia trachomatis infection in mice. Infect Immun 66: 4030-4035.
14. Johnson RM (2004) Murine oviduct epithelial cell cytokine responses to Chlamydia muridarum infection include interleukin-12-p70 secretion. Infect Immunol 72: 3951-3960.
15. Kelly KA, Robinson E & Rank RG (1996) Initial route of antigen administration alters the T cell cytokine profile produced in response to the mouse pneumonitis biovar of Chlamydia trachomatis following genital infection. Infect Immunol 64: 4976-4983.
16. Kinnunen A, Paavonen J & Surcel HM (2001) Heat shock protein 60 specific T cell response in chlamydial infection. Scand J Immunol 54: 76-81.
17. Lehtinen M & Paavonen J (1994) Heat shock proteins in the immunopathogenesis of chlamydial pelvic inflammatory disease. Proceedings of the Seventh International Symposium on Human Chlamydial Infections (Orfila J, ed) pp. 599-610. Editrice Esculapio, Bologna.
18. Mittal A, Kapur S & Gupta S (1996) Host immune response in Chlamydial cervicitis. Br J Biomed Scij 53: 941-947.
19. Morisset MR, Beaulieu R & Ravaoarinoro M (2006) Sustain interleukin-6 and interleukin-8 expression following infection with Chlamydia trachomatis serovar L2 in a HeLa/THP-1 cell co-culture model. Scand J Immunol 63: 199-207.
20. Mosmann TR & Moore KW (1991) The role of IL-10 in cross-regulation of Th1 and Th2 responses. Immunol Today 12: A49-A53.
21. Openshaw P, Murphy EE & Hosken NA (1995) Heterogeneity of intracellular cytokine synthesis at the single cell level in polarized T helper-1 and T helpher-2 populations. J Exp Med 182: 1357-1367.
22. Rietmeijer CA, van Bemmelen R, Judson FN & Douglas JM Jr (2002) Incidence and increased infection rates of Chlamydia trachomatis amongmale and female patients in an STD clinic: implications for screening and rescreening. Sex Trans Dis 25: 65-72.
23. Starnbach MN, Bevan MJ & Lampe MF (1994) Protective cytotoxic T lymphocyte are induced during murine infection with Chlamydia trachomatis. J Immunol 153: 5183-5189.
24. Tripp CS, Wolf SF & Unanue ER (1993) Interleukin 12 and tumor necrosis factor a are costimulators of interferon g production by natural killer cells in severe combined immunodeficiency mice with listeriosis and interlukin-10 is a physiologic antagonist. Proc Natl Acad Sci USA 90: 3725-3729.
25. Williams DM, Schachter J, Coalson JE & Grubbs B (1984) Cellular immunity to the mouse pneumnitis agent. J Infect Dis 149: 630-639.
26. Williams DM, Grubbs BG, Darville T, Kelly K & Rank RG (1998) A role for interlukin-6 in host defense against murine Chlamydia trachomatis infection. Infect Immun 66: 4564-4567.
27. Witkin SS, Jeremias J, Toth M & Ledger WJ (1994) Proliferative response to conserved epitopes of the Chlamydia trachomatis and human 60-kilodalton heat-shock proteins by lymphocyte fromwomen with salpingitis. Am J Obstet Gynecol 171: 455-460.
28. Yu JL, Yu P & Li LX (2003) HeLa cells secrete interleukin-8 and interlukin-10 response to Chlamydia trachomatis entry. Hunan Yi Ke Da Xue Xue Bao 2: 174-176.
29. Zhang JP & Stephens RS (1992) Mechanism of Chlamydia trachomatis attachment to eukaryotic host cells. Cell 69: 861-869.