Beryllium-induced TNF-α production is transcription-dependent in chronic beryllium disease

American Journal of Respiratory Cell and Molecular Biology

Volumn 36, Issue 2, 2007, Pages 191-200

  Sawyer, Richard T ^a   Fontenot, Andrew P ^b   Barnes, Tristan A ^b   Parsons, Charles E ^b   Tooker, Brian C ^b   Maier, Lisa A ^b   Gillespie, May M ^b   Gottschall, E Brigitte ^b   Silveira, Lori ^b   Hagman, James ^b   Newman, Lee S ^b  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b NONE

Author keywords

Cytokines; Gene regulation; Granuloma; Lung; T lymphocytes

Indexed keywords

2 AMINOPURINE; BERYLLIUM; BETA ACTIN; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 6; INTERLEUKIN 7; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MELANOMA GROWTH STIMULATORY ACTIVITY FACTOR; MESSENGER RNA; PENTOXIFYLLINE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ANTIGEN PRESENTATION; ARTICLE; BERYLLIOSIS; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; CLINICAL ARTICLE; CYTOKINE PRODUCTION; FEMALE; HUMAN; LUNG LAVAGE; MALE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION;

ADULT; BERYLLIOSIS; BERYLLIUM; BRONCHOALVEOLAR LAVAGE FLUID; CD4-POSITIVE T-LYMPHOCYTES; CELL SEPARATION; FEMALE; GENE DOSAGE; HUMANS; KINETICS; LIPOPOLYSACCHARIDES; MALE; MIDDLE AGED; NF-KAPPA B; NUCLEAR PROTEINS; RNA PRECURSORS; RNA, MESSENGER; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 33846939269     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2006-0021TR     Document Type: Article

References (38)

1. Sawyer RT, Maier LA, Kittle LA, Newman LS. Chronic beryllium disease: A model interaction between innate and acquired immunity. Int Immunopharmacol 2002;2:249-261.
2. + T cells in patients with chronic beryllium disease. J Clin Invest 2002;110:1473-1482.
3. Richeldi L, Sorrentino R, Saltini C. HLA-DPB1 glutamate 69: a genetic marker of beryllium disease. Science 1999;262:242-244.
4. Saltini C, Winestock K, Kirby M, Pinkston P, Crystal RG. Maintenance of alveolitis in patients with chronic beryllium disease by beryllium-specific helper T cells. N Engl J Med 1989;320:1103-1109.
5. Mroz MM, Kreiss K, Lezotte DC, Campbell PA, Newman LS. Re-examination of the blood lymphocyte transformation test in the diagnosis of chronic beryllium disease. J Allergy Clin Immunol 1991;88:54-60.
6. Maier LA, Sawyer RT, Bauer RA, Kittle LA, Lympany P, McGrath D, DuBois R, Daniloff E, Rose CS, Newman LS. High beryllium-stimulated TNF-α is associated with the -308 TNF-α promoter polymorphism and with clinical severity in chronic beryllium disease. Am J Respir Crit Care Med 2001;164:1192-1199.
7. + T cells is mediated by HLA-DP. Am J Respir Cell Mol Biol 2004;31:122-130.
8. Yang Y, Chang JF, Parnes JR, Fathman CG. T cell receptor (TCR) engagement leads to activation-induced splicing of tumor necrosis factor (TNF) nuclear pre-mRNA. J Exp Med 1998;188:246-254.
9. Swanson BJ, Murakami M, Mitchell TC, Kappler J, Marrack P. RANTES production by memory phenotype T cells is controlled by a posttranscriptional, TCR-dependent process. Immunity 2002;17:605-615.
10. Tracey KJ, Cerami A. Tumor necrosis factor, other cytokines and disease. Annu Rev Cell Biol 1993;9:317-343.
11. Jarrous N, Osman F, Kaempfer R. 2-Aminopurine selectively inhibits splicing of tumor necrosis factor alpha mRNA. Mol Cell Biol 1996;16:2814-2822.
12. Doherty GM, Jensen C, Alexander R, Buresh CM, Norton JA. Pentoxifylline suppression of tumor necrosis factor gene transcription. Surgery 1991;110:192-198.
13. Strieter RM, Remick DG, Ward PA, Spengler RN, Lynch JP, Larrick J, Kuunkel SL. Cellular and molecular regulation of tumor necrosis factor-alpha production by pentoxifylline. Biochem Biophys Res Commun 1988;155:1230-1236.
14. Newman LS, Kreiss K, King TR Jr, Seay S, Campbell PA. Pathologic and immunologic alterations in early stages of beryllium disease: reexamination of disease definition and natural history. Am Rev Respir Dis 1989;139:1479-1486.
15. Rossman MD, Stubbs J, Lee CW, Argyris E, Magira E, Monos D. Human leukocyte antigen class II amino acid epitopes. Susceptibility and progression markers for beryllium hypersensitivity. Am J Respir Crit Care Med 2002;65:788-794.
16. Ferris BG. Epidemiology standardization project. Am Rev Respir Dis 1978;118:1-120.
17. Kreiss K, Mroz MM, Zhen B, Martyny JW, Newman LS. Epidemiology of beryllium sensitization and disease in nuclear workers. Am Rev Respir Dis 1993;148:985-991.
18. Tinkle SS, Newman LS. Beryllium-stimulated release of tumor necrosis factor-α, interleukin-6, and their soluble receptors in chronic beryllium disease. Am J Respir Crit Care Med 1997;156:1884-1891.
19. Walters LC, Schwartz MI, Cherniak RM. Idiopathic pulmonary fibrosis: pretreatment bronchoalveolar lavage cellular constituents and their relationship with lung histopathology and clinical response to therapy. Am Rev Respir Dis 1997;135:696-704.
20. + T cells. J Clin Invest 2003;112:776-784.
21. Hamada H, Sawyer RT, Kittle LA, Newman LS. Beryllium-stimulation does not activate transcription factors in a mouse hybrid macrophage cell line. Toxicology 2002;143:249-261.
22. Bost TW, Riches DWG, Schumacher B, Carre PC, Kahn TZ, Martienez JA, Newman LS. Alveolar macrophages from patients with beryllium disease and sarcoidosis express increased levels of mRNA for tumor necrosis factor-α and interleukin-6 but not interleukin 1β. Am J Respir Cell Mol Biol 1994;10:506-513.
23. Sawyer RT, Day BJ, Fadok VA, Chiarappa-Zucca M, Maier LA, Fontenot AP, Silveira L, Newman LS. Beryllium-ferritin: lymphocyte proliferation and macrophage apoptosis in chronic beryllium disease. Am J Respir Cell Mol Biol 2004;31:470-477.
24. + T cells in patients with beryllium-induced disease. J Allergy Clin Immunol 2005;115:1036-1042.
25. Tinkle SS, Kittle LA, Schumacher BA, Newman LS. Beryllium induces IL-2 and IFN-γ in berylliosis. J Immunol 1997;158:518-526.
26. Tinkle SS, Kittle LA, Newman LS. Partial IL-10 inhibition of the cell-mediated immune response in chronic beryllium disease. J Immunol 1999;163:2747-2753.
27. Maier LA, Sawyer RT, Tinkle SS, Kittle LA, Barker EA, Balkissoon R, Rose C, Newman LS. IL-4 fails to regulate in vitro beryllium-induced cytokines in berylliosis. Eur Respir J 2001;17:403-415.
28. Amicosante M, Berretta F, Franchi A, Rogliani P, Dotti C, Losi M, Dweik R, Saltini C. HLA-DP-unrestricted TNF-α release in beryllium-stimulated peripheral blood mononuclear cells. Eur Respir J 2002;20:1174-1178.
29. Hong-Geller E, Pardington PE, Cary RB, Sauer NN, Gupta G. Chemokine regulation in response to beryllium exposure in human peripheral blood mononuclear and dendritic cells. Toxicology 2006;218:216-228.
30. Maier LA. Genetic and exposure risks for chronic beryllium disease. Clin Chest Med 2002;23:827-839.
31. Han J, Thompson P, Beutler B. Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis factor synthesis at separate points in the signaling pathway. J Exp Med 1990;172:391-394.
32. Han J, Huez G, Beutler B. Interactive effects of the tumor necrosis factor promoter and 3′-untranslated regions. J Immunol 1991;146:1843-1848.
33. Steer JH, Kroeger KM, Abraham LJ, Joyce DA. Glucocorticoids suppress tumor necrosis factor-α expression by human monocytic THP-1 cells by suppressing transactivation through adjacent NF-κB and c-Jun-activating transcription factor-2 binding sites in the promoter. J Biol Chem 2000;275:18432-18440.
34. Serbina NV, Pamer EG. Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2. Nat Immunol 2006;7:311-317.
35. Serbina NV, Salazar-Mather TP, Biron CA, Kuziel WA, Pamer EG. TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection. Immunity 2003;19:59-70.
36. Sawyer RT, Kittle LA, Hamada H, Newman LS, Campbell PA. Beryllium-stimulated production of tumor necrosis factor-α by a mouse hybrid macrophage cell line. Toxicology 2000;143:235-247.
37. Conono BP, Campbell PA. Production of mouse inflammatory macrophage hybridomas. J Tissue Cult Methods 1992;14:3-8.
38. Sawyer RT, Abraham JL, Daniloff E, Newman LS. Secondary ion mass spectroscopy demonstrates retention of beryllium in chronic beryllium disease granulomas. J Occup Environ Med 2005;47:1218-1226.