Mapping of human cerebral sigma1 receptors using positron emission tomography and [11C]SA4503

NeuroImage

Volumn 35, Issue 1, 2007, Pages 1-8

  Sakata, Muneyuki ^a   Kimura, Yuichi ^b   Naganawa, Mika ^b,c   Oda, Keiichi ^b   Ishii, Kenji ^b   Chihara, Kunihiro ^a   Ishiwata, Kiichi ^b  

^a NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^c JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 (3,4 DIMETHOXYPHENETHYL) 4 (3 PHENYLPROPYL)PIPERAZINE C 11; HALOPERIDOL; RADIOLIGAND; RADIOPHARMACEUTICAL AGENT; SIGMA 1 OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BINDING AFFINITY; BINDING SITE; BRAIN; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG BINDING; HUMAN; HUMAN EXPERIMENT; IMAGE DISPLAY; KINETICS; MALE; MENTAL DISEASE; METABOLITE; NEUROLOGIC DISEASE; NONLINEAR SYSTEM; NORMAL HUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS;

ADULT; BIOTRANSFORMATION; BRAIN; BRAIN CHEMISTRY; BRAIN MAPPING; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DATA INTERPRETATION, STATISTICAL; DOPAMINE ANTAGONISTS; HALOPERIDOL; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; NONLINEAR DYNAMICS; PIPERAZINES; POSITRON-EMISSION TOMOGRAPHY; RADIOLIGAND ASSAY; RADIOPHARMACEUTICALS; RECEPTORS, SIGMA;

EID: 33846936266     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2006.11.055     Document Type: Article

References (36)

1. Ardekani B.A., Braun M., Hutton B.F., Kanno I., and Iida H. A fully automatic multimodality image registration algorithm. J. Comput. Assist. Tomogr. 19 (1995) 615-623
2. Bard Y. Weighted least squares. Nonlinear Parameter Estimation (1974), Academic Press, New York 56-57 Chap. 4-3
3. Coleman T., and Branch M.A. Optimization Toolbox User's Guide (1999), MathWorks Inc., Natick, MA
4. Fujiwara T., Watanuki S., Yamamoto S., Miyake M., Seo S., Itoh M., Ishii K., Orihara H., Fukuda H., Satoh T., Kitamura K., Tanaka K., and Takahashi S. Performance evaluation of a large axial field-of-view PET scanner: SET-2400W. Ann. Nucl. Med. 11 (1997) 307-313
5. Hashimoto K., and Ishiwata K. Sigma receptor ligands: possible application as therapeutic drugs and as radiopharmaceuticals. Curr. Pharm. Des. 12 (2006) 3915-3928
6. Helmeste D.M., Tang S.W., Bunney Jr. W.E., Potkin S.G., and Jones E.G. Decrease in sigma but no increase in striatal dopamine D4 sites in schizophrenic brains. Eur. J. Pharmacol. 314 3 (1996) R3-R5
7. Ichise M., Toyama H., Innis R.B., and Carson R.E. Strategies to improve neuroreceptor parameter estimation by linear regression analysis. J. Cereb. Blood Flow Metab. 22 (2002) 1271-1281
8. 11C]SA4503. Synapse 40 (2001) 235-237
9. 2-like receptor ligands. Nucl. Med. Biol. 30 (2003) 429-434
10. 2-like receptors. Ann. Nucl. Med. 20 (2006) 569-573
11. Jansen K.L., Faull R.L., Storey P., and Leslie R.A. Loss of sigma binding sites in the CA1 area of the anterior hippocampus in Alzheimer's disease correlates with CA1 pyramidal cell loss. Brain Res. 623 (1993) 299-302
12. Junien J.L., and Leonard B.E. Drugs acting on sigma and phencyclidine receptors: a review of their nature, function and possible therapeutic importance. Clin. Neuropharmacol. 12 (1989) 353-374
13. 1 receptors in the cat brain. Ann. Nucl. Med. 14 (2000) 285-292
14. 1 receptors. Nucl. Med. Biol. 27 (2000) 255-261
15. 1 receptors in the aged monkey brain. Neurobiol. Aging 24 (2003) 745-752
16. 11C]8-dicyclopropylmethyl-1-methyl-3-propylxanthine. Nucl. Med. Biol. 31 (2004) 975-981
17. 11C]flumazenil kinetics for the estimation of ligand transport rate and receptor distribution using positron emission tomography. J. Cereb. Blood Flow Metab. 11 (1991) 735-744
18. 11C-methyl]-(-)-cocaine PET studies in human subjects. J. Cereb. Blood Flow Metab. 10 (1990) 740-747
19. 18F]FBFPA): a potential fluorine-18 labeled PET radiotracer for imaging sigma-1 receptors in the CNS. Synapse 58 (2005) 267-274
20. 15O and positron emission tomography. J. Cereb. Blood Flow Metab. 7 (1987) 421-426
21. Mash D.C., and Zabetian C.P. Sigma receptors are associated with cortical limbic areas in the primate brain. Synapse 12 (1992) 195-205
22. 1 receptor agonist. CNS Drug Rev. 4 (1998) 1-24
23. 1 receptor agonist. Eur. J. Pharmacol. 306 (1996) 271-279
24. Mintun M.A., Raichle M.E., Kilbourn M.R., Wooten G.F., and Welch M.J. A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography. Ann. Neurol. 15 (1984) 217-227
25. 1 receptors in Parkinson's disease. Acta Neurol. Scand. 112 (2005) 103-107
26. Nelder J., and Mead R. A simplex method for function minimization. Comput. J. 7 (1965) 308-313
27. Shibuya H., Mori H., and Toru M. Sigma receptors in schizophrenic cerebral cortices. Neurochem. Res. 17 (1992) 983-990
28. Slifstein M., and Laruelle M. Effects of statistical noise on graphic analysis of PET neuroreceptor studies. J. Nucl. Med. 41 (2000) 2083-2088
29. 123I]TPCNE-a novel SPET tracer for the sigma-1 receptor: first human studies and in vivo haloperidol challenge. Synapse 60 (2006) 109-117
30. Su T.P. Delineating biochemical and functional properties of sigma receptors: emerging concepts. Crit. Rev. Neurobiol. 7 (1993) 187-203
31. Su T.P., and Hayashi T. Understanding the molecular mechanism of sigma-1 receptors: towards a hypothesis that sigma-1 receptors are intracellular amplifiers for signal transduction. Curr. Med. Chem. 10 (2003) 2073-2080
32. 11C]SA4503: a feasibility study. J. Nucl. Med. 45 (2004) 1939-1946
33. 11C]MDL 100,907. J. Cereb. Blood Flow Metab. 20 (2000) 899-909
34. 123I]-1-(iodopropen-2-yl)-4-[(4-cyanophenoxy)methyl]piperidine. J. Med. Chem. 40 (1997) 1657-1667
35. Weissman A.D., Su T.P., Hedreen J.C., and London E.D. Sigma receptors in post-mortem human brains. J. Pharmacol. Exp. Ther. 247 (1988) 29-33
36. Weissman A.D., Casanova M.F., Kleinman J.E., London E.D., and De Souza E.B. Selective loss of cerebral cortical sigma, but not PCP binding sites in schizophrenia. Biol. Psychiatry 29 (1991) 41-54