Clinical laboratories on a chip for human immunodeficiency virus assay

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

Volumn 7 VOLS, Issue , 2005, Pages 1274-1277

  Guo, Wen Peng ^a   Ma, Xue Mei ^a   Zeng, Yi ^a,b  

^a BEIJING UNIVERSITY OF TECHNOLOGY   (China)

^b CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

Author keywords

Clinical diagnosis; HIV; Lab on a chip; PCR

Indexed keywords

BIOMEDICAL ENGINEERING; CHIP SCALE PACKAGES; COMPUTER AIDED DIAGNOSIS; ELECTRONIC MEDICAL EQUIPMENT; IMMUNOLOGY; INTEGRATED CIRCUIT LAYOUT; VIRUSES;

CLINICAL DIAGNOSIS; LASER INDUCED FLUORESCENCE SYSTEM; SAMPLE PREPARATION; SIGNAL AMPLIFICATION;

BIOASSAY;

EID: 33846922548     PISSN: 05891019     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (19)

1. B. H. Weigl, K. Hedine, "Lab-on-a-chip-based separation and detection technology for clinical diagnostics," American Clinic Lab, vol. 49, no. 10, pp. 8-13, Mar. 2002.
2. A. Manz, N. Graber, H. M. Widmer, "Miniaturized total chemical analysis system: a novel concept for chemical sensing," Sensors and Actuators, B1, vol. 14, no. 1, pp. 244-248, Jan. 1990.
3. E. Vespoorte, "Microfluidic chips for clinical and forensic analysis," Electrophoresis, vol. 23, pp. 677-712, 2002.
4. R. Ehrnstrom, "Miniaturization and integration: Challenges and breakthroughs in microfluidics," Lab. Chip, vol. 2, pp. 26N-30N, 2002.
5. R. Service, "Lab. on a chip: Coming soon: The pocket DNA sequencer," Science, vol. 282, no. 5338, pp. 399-401, 1998.
6. F. Vinet, P. Chaton, and Y. Fouillet, "Microarrays and microfluidic devices; Miniaturized systems for biological analysis," Microelectron.Eng., vol. 61-62, pp. 41-47, 2002.
7. C. Malins, M. Niggemann, and B.D. MacCraith, "Multi-analyte optical chemical sensor employing a plastic substrate," Measure. Sci. Tech., vol. 11, no. 8, pp. 1105-1110, Aug. 1, 2000.
8. P. Bergstrom, K.Wise, S. Patel, and J. Schwank, "A micromachined surface work-function gas sensor for low-pressure oxygen detection," Sens. Actuators B, vol. 42, no. 3, pp. 195-204, Aug. 1997.
9. L. Cao, S. Mantell, and D. Polla, "Design and simulation of an implantable medical drug delivery system using microelectromechanical systems technology," Sens. Actuators, vol. A 94, pp. 117-125, 2001.
10. Joint United Nations Programme on HIV/AIDS (UNAIDS), global Summary of the HIV/AIDS Epidemic, December 2004. Available: http://www.unaids.org/wad2004/ report_pdf.html
11. J. G. Bartlett. Serologic tests for the diagnosis of HIV infection, Official Reprint from UpToDate. Available: http://www.uptodate.com
12. R. A. Goldsby, T. J. Kindt, B. A. Osborne. "AIDS and other immunodefi-ciencies," In Kuby Immunology, 4th ed. New York: W.H. Freeman and Company, 2000, pp. 467-96.
13. L. Gurtler, "Difficulties and strategies of HIV diagnosis," Lancet, vol. 348, pp. 176-179, 1996.
14. T. D. Ly, S. Laperche, A. M. Courouce, "Early detection of human immunodeficiency virus infection using third and fourth generation screening assays," Eur J Clin Microbiol Infect Dis, vol. 20, pp. 104-10, 2001.
15. B. S. Parekh, M. S. Kennedy, T. Dobbs, "Quantitative detection of increasing HIV type 1 antibodies after seroconversion: a simple assay for detecting recent HIV infection and estimating incidence," AIDS Res Hum Retroviruses, vol. 18, pp. 295-307, 2002.
16. R. S. Janssen, G. A. Satten, S. L. Stramer, "New testing strategy to detect early HIV-1 infection for use in incidence estimates and for clinical prevention purposes," JAMA, vol. 280, pp. 42-48, 1998.
17. J. M. Barletta, D. C. Edelman, N. T. Constantine, "Lowering the detection limits of HIV-1 viral load using real-time immuno-PCR for HIV-1 p24 antigen," Am J Clin Pathol, vol. 122. pp: 20-27, 2004.
18. H.A. Erlich. PCR Technology: Principles and Applications for DNA amplification. Stockton Press, 1989.
19. J. Ankur, N. Kevin, M. C. Angie, L. N. Jiang, G. Kenneth, "Design fabrication and thermal characterization of a MEMS device for control of nerve cell growth," in Proc of International Mechanical Engineering Congress & Exposition IMECE'03, Washington, D.C., pp. 1-7