Determination and analysis of the DNA sequence of highly attenuated herpes simplex virus type 1 mutant HF10, a potential oncolytic virus

Microbes and Infection

Volumn 9, Issue 2, 2007, Pages 142-149

  Ushijima, Yoko ^a   Luo, Chenhong ^a   Goshima, Fumi ^a   Yamauchi, Yohei ^a   Kimura, Hiroshi ^a   Nishiyama, Yukihiro ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

DNA sequence; Herpes simplex virus type 1; Oncolytic virus; Pathogenicity

Indexed keywords

ONCOLYTIC VIRUS;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; GENE DELETION; GENE EXPRESSION; GENE INSERTION; GENETIC ORGANIZATION; HERPES SIMPLEX VIRUS 1; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SYNCYTIUM; VIRUS ATTENUATION; VIRUS GENOME; VIRUS MUTANT; VIRUS REPLICATION; VIRUS STRAIN; VIRUS VIRULENCE;

AMINO ACID SUBSTITUTION; ANIMALS; BASE SEQUENCE; CELL LINE; CERCOPITHECUS AETHIOPS; DNA MUTATIONAL ANALYSIS; DNA, VIRAL; FRAMESHIFT MUTATION; GENE EXPRESSION; GENOME, VIRAL; HERPESVIRUS 1, HUMAN; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; RECOMBINATION, GENETIC; SEQUENCE DELETION; SEQUENCE HOMOLOGY, AMINO ACID; VIRAL PROTEINS;

HUMAN HERPESVIRUS 1; MUS;

EID: 33846885661     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2006.10.019     Document Type: Article

References (32)

1. McGeoch D.J., Dalrymple M.A., Davison A.J., Dolan A., Frame M.C., McNab D., Perry L.J., Scott J.E., and Taylor P. The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1. J. Gen. Virol. 69 Pt 7 (1988) 1531-1574
2. Roizman B., and Knipe D.M. In: Fields B.N., Knipe D.M., and Howley P.M. (Eds). Fields Virology (2001), Lippincott Williams & Wilkins, Philadelphia, PA 2399-2460
3. Dolan A., Jamieson F.E., Cunningham C., Barnett B.C., and McGeoch D.J. The genome sequence of herpes simplex virus type 2. J. Virol. 72 (1998) 2010-2021
4. Nishiyama Y., Kimura H., and Daikoku T. Complementary lethal invasion of the central nervous system by non-neuroinvasive herpes simplex virus types 1 and 2. J. Virol. 65 (1991) 4520-4524
5. Takakuwa H., Goshima F., Nozawa N., Yoshikawa T., Kimata H., Nakao A., Nawa A., Kurata T., Sata T., and Nishiyama Y. Oncolytic viral therapy using a spontaneously generated herpes simplex virus type 1 variant for disseminated peritoneal tumor in immunocompetent mice. Arch. Virol. 148 (2003) 813-825
6. Jiang Y.M., Daikoku T., Yamamoto M., Morishima T., and Nishiyama Y. Growth and cytopathogenicity of herpes simplex virus in a macrophage cell line, RAW264: a good indicator of intraperitoneal pathogenicity. Microbiol. Immunol. 39 (1995) 905-909
7. Teshigahara O., Goshima F., Takao K., Kohno S., Kimata H., Nakao A., and Nishiyama Y. Oncolytic viral therapy for breast cancer with herpes simplex virus type 1 mutant HF 10. J. Surg. Oncol. 85 (2004) 42-47
8. Kohno S., Luo C., Goshima F., Nishiyama Y., Sata T., and Ono Y. Herpes simplex virus type 1 mutant HF10 oncolytic viral therapy for bladder cancer. Urology 66 (2005) 1116-1121
9. Mori I., Liu B., Goshima F., Ito H., Koide N., Yoshida T., Yokochi T., Kimura Y., and Nishiyama Y. HF10, an attenuated herpes simplex virus (HSV) type 1 clone, lacks neuroinvasiveness and protects mice against lethal challenge with HSV types 1 and 2. Microbes Infect. 7 (2005) 1492-1500
10. Nakao A., Kimata H., Imai T., Kikumori T., Teshigahara O., Nagasaka T., Goshima F., and Nishiyama Y. Intratumoral injection of herpes simplex virus HF10 in recurrent breast cancer. Ann. Oncol. 15 (2004) 988-989
11. Kimata H., Imai T., Kikumori T., Teshigawara O., Nagasaka T., Goshima F., Nishiyama Y., and Nakao A. Pilot study of oncolytic viral therapy using mutant herpes simplex virus "HF10" against recurrent metastatic breast cancer. Ann. Surg. Oncol. 13 (2006) 1078-1084
12. Fujimoto Y., Mizuno T., Sugiura S., Goshima F., Kohno S., Nakashima T., and Nishiyama Y. Intratumoral injection of herpes simplex virus HF10 in recurrent head and neck squamous cell carcinoma. Acta Otolaryngol. 126 (2006) 1115-1117
13. Takakuwa H., Goshima F., Koshizuka T., Murata T., Daikoku T., and Nishiyama Y. Herpes simplex virus encodes a virion-associated protein which promotes long cellular processes in over-expressing cells. Genes Cells 6 (2001) 955-966
14. Brown J. Effect of gene location on the evolutionary rate of amino acid substitutions in herpes simplex virus proteins. Virology 330 (2004) 209-220
15. Koshizuka T., Goshima F., Takakuwa H., Nozawa N., Daikoku T., Koiwai O., and Nishiyama Y. Identification and characterization of the UL56 gene product of herpes simplex virus type 2. J. Virol. 76 (2002) 6718-6728
16. Koshizuka T., Kawaguchi Y., and Nishiyama Y. Herpes simplex virus type 2 membrane protein UL56 associates with the kinesin motor protein KIF1A. J. Gen. Virol. 86 (2005) 527-533
17. Koshizuka T., Kawaguchi Y., Goshima F., Mori I., and Nishiyama Y. Association of two membrane proteins encoded by herpes simplex virus type 2, UL11 and UL56. Virus Genes 32 (2006) 153-163
18. Kehm R., Rosen-Wolff A., and Darai G. Restitution of the UL56 gene expression of HSV-1 HFEM led to restoration of virulent phenotype; deletion of the amino acids 217 to 234 of the UL56 protein abrogates the virulent phenotype. Virus Res. 40 (1996) 17-31
19. Adams R., Cunningham C., Davison M.D., MacLean C.A., and Davison A.J. Characterization of the protein encoded by gene UL49A of herpes simplex virus type 1. J. Gen. Virol. 79 Pt 4 (1998) 813-823
20. Crump C.M., Bruun B., Bell S., Pomeranz L.E., Minson T., and Browne H.M. Alphaherpesvirus glycoprotein M causes the relocalization of plasma membrane proteins. J. Gen. Virol. 85 (2004) 3517-3527
21. Carter K.L., Ward P.L., and Roizman B. Characterization of the products of the UL43 gene of herpes simplex virus 1: potential implications for regulation of gene expression by antisense transcription. J. Virol. 70 (1996) 7663-7668
22. Yamada H., Jiang Y.M., Oshima S., Daikoku T., Yamashita Y., Tsurumi T., and Nishiyama Y. Characterization of the UL55 gene product of herpes simplex virus type 2. J. Gen. Virol. 79 Pt 8 (1998) 1989-1995
23. Efstathiou S., and Preston C.M. Towards an understanding of the molecular basis of herpes simplex virus latency. Virus Res. 111 (2005) 108-119
24. Perng G.C., Dunkel E.C., Geary P.A., Slanina S.M., Ghiasi H., Kaiwar R., Nesburn A.B., and Wechsler S.L. The latency-associated transcript gene of herpes simplex virus type 1 (HSV-1) is required for efficient in vivo spontaneous reactivation of HSV-1 from latency. J. Virol. 68 (1994) 8045-8055
25. Gupta A., Gartner J.J., Sethupathy P., Hatzigeorgiou A.G., and Fraser N.W. Anti-apoptotic function of a microRNA encoded by the HSV-1 latency-associated transcript. Nature 442 (2006) 82-85
26. Brandt C.R., Kolb A.W., Shah D.D., Pumfery A.M., Kintner R.L., Jaehnig E., and Van Gompel J.J. Multiple determinants contribute to the virulence of HSV ocular and CNS infection and identification of serine 34 of the US1 gene as an ocular disease determinant. Invest. Ophthalmol. Vis. Sci. 44 (2003) 2657-2668
27. Chou J., Kern E.R., Whitley R.J., and Roizman B. Mapping of herpes simplex virus-1 neurovirulence to gamma 1 34.5, a gene nonessential for growth in culture. Science 250 (1990) 1262-1266
28. Shen Y., and Nemunaitis J. Herpes simplex virus 1 (HSV-1) for cancer treatment. Cancer Gene Ther. 13 (2006) 975-992
29. Spear P.G. In: Bentz J. (Ed). Viral Fusion Mechanisms (1993), CRC Press, Boca Raton, FL 201-232
30. Engel J.P., Boyer E.P., and Goodman J.L. Two novel single amino acid syncytial mutations in the carboxy terminus of glycoprotein B of herpes simplex virus type 1 confer a unique pathogenic phenotype. Virology 192 (1993) 112-120
31. Diakidi-Kosta A., Michailidou G., Kontogounis G., Sivropoulou A., and Arsenakis M. A single amino acid substitution in the cytoplasmic tail of the glycoprotein B of herpes simplex virus 1 affects both syncytium formation and binding to intracellular heparan sulfate. Virus Res. 93 (2003) 99-108
32. Klupp B.G., Altenschmidt J., Granzow H., Fuchs W., and Mettenleiter T.C. Identification and characterization of the pseudorabies virus UL43 protein. Virology 334 (2005) 224-233