메뉴 건너뛰기




Volumn 40, Issue 1, 1996, Pages 17-31

Restitution of the UL56 gene expression of HSV-1 HFEM led to restoration of virulent phenotype; deletion of the amino acids 217 to 234 of the UL56 protein abrogates the virulent phenotype

Author keywords

DNA sequencing; Expression vector pMa1 c2; Herpesviridae; Immunoblot; Immunofluorescence; Maltose binding protein; Pathogenicity; Polymerase chain reaction; Recombinant virus; Tree shrew (Tupaia)

Indexed keywords

AMINO ACID SEQUENCE; ARTICLE; GENE EXPRESSION; HERPES SIMPLEX VIRUS 1; IMMUNOFLUORESCENCE; MOLECULAR CLONING; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; VIRUS GENOME; VIRUS MUTATION; VIRUS VIRULENCE;

EID: 0029920846     PISSN: 01681702     EISSN: None     Source Type: Journal    
DOI: 10.1016/0168-1702(96)80248-6     Document Type: Article
Times cited : (31)

References (38)
  • 1
    • 0025882349 scopus 로고
    • A dictionary of sites and patterns in proteins
    • Bairoch, A. (1991) A dictionary of sites and patterns in proteins. Nucl. Acids Res. 19, 2241-2245.
    • (1991) Nucl. Acids Res. , vol.19 , pp. 2241-2245
    • Bairoch, A.1
  • 2
    • 0022560236 scopus 로고
    • A sequence in HpaI-P fragment of herpes simplex virus-1 DNA determines intraperitoneal virulence in mice
    • Becker, Y., Hadar, J., Tabor, E., Ben-Hur, T., Raibstein, I., Rösen, A. and Darai, G. (1986) A sequence in HpaI-P fragment of herpes simplex virus-1 DNA determines intraperitoneal virulence in mice. Virology 149, 255-259.
    • (1986) Virology , vol.149 , pp. 255-259
    • Becker, Y.1    Hadar, J.2    Tabor, E.3    Ben-Hur, T.4    Raibstein, I.5    Rösen, A.6    Darai, G.7
  • 3
    • 0023932530 scopus 로고
    • HSV-1 HpaI-P DNA sequence determining intraperitoneal pathogenicity is required for transcription of viral immediate early genes in macrophages
    • Ben-Hur, T., Rösen-Wolff, A., Lamade, W., Darai, G. and Becker, Y. (1988) HSV-1 HpaI-P DNA sequence determining intraperitoneal pathogenicity is required for transcription of viral immediate early genes in macrophages. Virology 163, 397-404.
    • (1988) Virology , vol.163 , pp. 397-404
    • Ben-Hur, T.1    Rösen-Wolff, A.2    Lamade, W.3    Darai, G.4    Becker, Y.5
  • 4
    • 0028155019 scopus 로고
    • Herpes simplex virus type 1 (HSV-1) UL56 gene is involved in viral intraperitoneal pathogenicity to immunocompetent mice
    • Berkowitz, C., Moyal, M., Rösen-Wolff, A., Darai, G. and Becker Y. (1994) Herpes simplex virus type 1 (HSV-1) UL56 gene is involved in viral intraperitoneal pathogenicity to immunocompetent mice. Arch. Virol. 134, 73-83.
    • (1994) Arch. Virol. , vol.134 , pp. 73-83
    • Berkowitz, C.1    Moyal, M.2    Rösen-Wolff, A.3    Darai, G.4    Becker, Y.5
  • 5
    • 0024444829 scopus 로고
    • Biochemical analysis of transcriptional activation by Jun: Differential activity of c-and v-jun
    • Bohmann, D. and Tijan, R. (1989) Biochemical analysis of transcriptional activation by Jun: differential activity of c-and v-jun. Cell 59, 709-717.
    • (1989) Cell , vol.59 , pp. 709-717
    • Bohmann, D.1    Tijan, R.2
  • 6
    • 0020065657 scopus 로고
    • Ocular disease pattern induced by herpes simplex virus is genetically determined by a specific region of viral DNA
    • Centifanto-Fitzgerald, Z.M., Yamagushi, T., Kaufman, H.E., Togon, M. and Roizman, B. (1982) Ocular disease pattern induced by herpes simplex virus is genetically determined by a specific region of viral DNA. J. Exp. Med. 155, 475-489.
    • (1982) J. Exp. Med. , vol.155 , pp. 475-489
    • Centifanto-Fitzgerald, Z.M.1    Yamagushi, T.2    Kaufman, H.E.3    Togon, M.4    Roizman, B.5
  • 7
    • 0025688373 scopus 로고
    • Mapping of herpes simplex-1 neurovirulence to γI 34.5, gene non-essential for growth in culture
    • Chou, J., Kern, E.R., Witley, R.J. and Roizman B. (1990) Mapping of herpes simplex-1 neurovirulence to γI 34.5, gene non-essential for growth in culture. Science 250, 1262-1266.
    • (1990) Science , vol.250 , pp. 1262-1266
    • Chou, J.1    Kern, E.R.2    Witley, R.J.3    Roizman, B.4
  • 8
    • 0017099460 scopus 로고
    • Neoplasmic transformation of rat embryo cells with herpes simplex virus
    • Darai, G. and Munk, K. (1976) Neoplasmic transformation of rat embryo cells with herpes simplex virus. Int. J. Cancer 18, 469-481.
    • (1976) Int. J. Cancer , vol.18 , pp. 469-481
    • Darai, G.1    Munk, K.2
  • 9
    • 0038895224 scopus 로고
    • Latency of herpes simplex virus in tree shrew; generation of intratypic recombinants of herpes simplex virus in vivo
    • Nijhoff, Boston
    • Darai, G. and Scholz, J. (1984) Latency of herpes simplex virus in tree shrew; generation of intratypic recombinants of herpes simplex virus in vivo. Latent Herpes Virus Infections in Veterinary Medicine. Nijhoff, Boston, pp. 21-32.
    • (1984) Latent Herpes Virus Infections in Veterinary Medicine , pp. 21-32
    • Darai, G.1    Scholz, J.2
  • 10
    • 0017805069 scopus 로고
    • Experimental infection of tupaia belangeri (tree shrews) with herpes simplex virus type 1 and 2
    • Darai, G., Schwaier, A., Komitowski, D. and Munk, K. (1978) Experimental infection of tupaia belangeri (tree shrews) with herpes simplex virus type 1 and 2. J. Infect. Dis. 137, 221-226.
    • (1978) J. Infect. Dis. , vol.137 , pp. 221-226
    • Darai, G.1    Schwaier, A.2    Komitowski, D.3    Munk, K.4
  • 11
    • 0022443708 scopus 로고
    • Specific inhibition of herpes simplex virus ribonucleotide reductase by synthetic peptides
    • Dutia, B.M., Frame, M.C., Subak-Sharpe J.H., Clark W.N. and Marsden, H.S. (1986) Specific inhibition of herpes simplex virus ribonucleotide reductase by synthetic peptides. Nature 321, 439-441.
    • (1986) Nature , vol.321 , pp. 439-441
    • Dutia, B.M.1    Frame, M.C.2    Subak-Sharpe, J.H.3    Clark, W.N.4    Marsden, H.S.5
  • 14
    • 0023680201 scopus 로고
    • Vectors that facilitate the expression and purification of foreign peptides in Escherichia coli by fusion to maltose-binding protein
    • Guan, C.D., Li, P., Riggs, P.D. and Inouye, H. (1988) Vectors that facilitate the expression and purification of foreign peptides in Escherichia coli by fusion to maltose-binding protein. Gene 67, 21-30.
    • (1988) Gene , vol.67 , pp. 21-30
    • Guan, C.D.1    Li, P.2    Riggs, P.D.3    Inouye, H.4
  • 15
    • 0038895222 scopus 로고
    • Anatomy of herpes simplex virus DNA: Evidence for four populations of their long and short components
    • Hayward, G.S., Jacob, R., Wadsworth, S.C. and Roizman, B. (1975) Anatomy of herpes simplex virus DNA: evidence for four populations of their long and short components. Proc. Natl. Acad. Sci. USA 72, 4243-4247.
    • (1975) Proc. Natl. Acad. Sci. USA , vol.72 , pp. 4243-4247
    • Hayward, G.S.1    Jacob, R.2    Wadsworth, S.C.3    Roizman, B.4
  • 16
    • 0028238677 scopus 로고
    • In vitro expression of UL56 gene of herpes simplex virus type 1; detection of UL56 gene product in infected cells and in virions
    • Kehm, R., Lorentzen, E., Rösen-Wolff, A. and Darai, G. (1994) In vitro expression of UL56 gene of herpes simplex virus type 1; detection of UL56 gene product in infected cells and in virions. Virus Res. 33, 55-66.
    • (1994) Virus Res. , vol.33 , pp. 55-66
    • Kehm, R.1    Lorentzen, E.2    Rösen-Wolff, A.3    Darai, G.4
  • 17
    • 2642699794 scopus 로고
    • Rapid and efficient site specific mutagenesis without phenotypic selection
    • Kunkel, T.A. (1985) Rapid and efficient site specific mutagenesis without phenotypic selection. Proc. Natl. Acad. Sci. USA 82, 488-492.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 488-492
    • Kunkel, T.A.1
  • 18
    • 0023613953 scopus 로고
    • Rapid and efficient site specific mutagenesis without phenotypic selection
    • Kunkel, T.A., Roberts, J.D. and Zakour, R.A. (1987) Rapid and efficient site specific mutagenesis without phenotypic selection. Methods Enzymol. 154, 367-382.
    • (1987) Methods Enzymol. , vol.154 , pp. 367-382
    • Kunkel, T.A.1    Roberts, J.D.2    Zakour, R.A.3
  • 20
    • 0024215242 scopus 로고
    • An Escherichia coli vector to express and purify foreign proteins by fusion to and separation from maltose-binding protein
    • Maina, C.V., Riggs, P.D., Grandea III, A.G., Slatko, B.E., Moran, S.L., Tagliamonte, J.A., McReynolds, L.A. and Guan, C.D. (1988) An Escherichia coli vector to express and purify foreign proteins by fusion to and separation from maltose-binding protein. Gene 74, 365-373.
    • (1988) Gene , vol.74 , pp. 365-373
    • Maina, C.V.1    Riggs, P.D.2    Grandea A.G. III3    Slatko, B.E.4    Moran, S.L.5    Tagliamonte, J.A.6    McReynolds, L.A.7    Guan, C.D.8
  • 21
    • 0023899276 scopus 로고
    • The complete DNA sequence of the long unique and adjoining parts of the long unique region in the genome of herpes simplex virus type 1
    • McGeoch, D.J., Dalrymple, M.A., Davison, A.J., Dolan, A., Frame, M.C., McNab, D., Perry, L., Scott, J.E. and Taylor, P. (1988) The complete DNA sequence of the long unique and adjoining parts of the long unique region in the genome of herpes simplex virus type 1. J. Gen. Virol. 69, 1531-1574.
    • (1988) J. Gen. Virol. , vol.69 , pp. 1531-1574
    • McGeoch, D.J.1    Dalrymple, M.A.2    Davison, A.J.3    Dolan, A.4    Frame, M.C.5    McNab, D.6    Perry, L.7    Scott, J.E.8    Taylor, P.9
  • 22
    • 0028054268 scopus 로고
    • The UL55 and UL56 genes of herpes simplex virus type 1 are not required for viral replication, intraperitoneal virulence, or establishment of latency in mice
    • Nash, T.C. and Spivac, J.G. (1994) The UL55 and UL56 genes of herpes simplex virus type 1 are not required for viral replication, intraperitoneal virulence, or establishment of latency in mice. Virology 204, 794-798.
    • (1994) Virology , vol.204 , pp. 794-798
    • Nash, T.C.1    Spivac, J.G.2
  • 23
    • 0023502309 scopus 로고
    • Detection of latency-related viral RNAs in trigeminal ganglia of rabbits latently infected with herpes simplex Type 1
    • Rock, D.L., Nesburn, A.B., Ghiasi, H., Ong, J., Lewis, T.L., Lokensgard, J.R. and Wechler, S.L. (1987) Detection of latency-related viral RNAs in trigeminal ganglia of rabbits latently infected with herpes simplex Type 1. J. Virol. 61, 3820-3826.
    • (1987) J. Virol. , vol.61 , pp. 3820-3826
    • Rock, D.L.1    Nesburn, A.B.2    Ghiasi, H.3    Ong, J.4    Lewis, T.L.5    Lokensgard, J.R.6    Wechler, S.L.7
  • 24
    • 0021751862 scopus 로고
    • Transduction of virulence in herpes simplex virus type 1 from a pathogenic to an apathogenic strain by a cloned viral DNA fragment
    • Rösen, A., Gelderblom, H. and Darai, G. (1985) Transduction of virulence in herpes simplex virus type 1 from a pathogenic to an apathogenic strain by a cloned viral DNA fragment. Med. Microbiol. Immunol. 173, 257-278.
    • (1985) Med. Microbiol. Immunol. , vol.173 , pp. 257-278
    • Rösen, A.1    Gelderblom, H.2    Darai, G.3
  • 25
    • 0021948621 scopus 로고
    • Mapping of the deletion in the genome of HSV-I strain HFEM responsible for its avirulent phenotype
    • Rösen, A. and Darai, G. (1985) Mapping of the deletion in the genome of HSV-I strain HFEM responsible for its avirulent phenotype. Med. Microbiol. Immunol. 173, 329-343.
    • (1985) Med. Microbiol. Immunol. , vol.173 , pp. 329-343
    • Rösen, A.1    Darai, G.2
  • 26
    • 0022534905 scopus 로고
    • Replacement of the deletion in the genome (0.762-0.789 m.U.) of avirulent HSV-1 HFEM using cloned MluI DNA fragment (0.7615-0.796 m.U.) of virulent HSV-1 F leads to generation of virulent intratypic recombinant
    • Rösen, A., Ernst, F., Koch, H.G., Gelderblom, H., Darai, G., Hadar, J., Tabor, E., Ben-Hur, T. and Becker, Y. (1986) Replacement of the deletion in the genome (0.762-0.789 m.u.) of avirulent HSV-1 HFEM using cloned MluI DNA fragment (0.7615-0.796 m.u.) of virulent HSV-1 F leads to generation of virulent intratypic recombinant. Virus Res. 5, 157-175.
    • (1986) Virus Res. , vol.5 , pp. 157-175
    • Rösen, A.1    Ernst, F.2    Koch, H.G.3    Gelderblom, H.4    Darai, G.5    Hadar, J.6    Tabor, E.7    Ben-Hur, T.8    Becker, Y.9
  • 27
    • 0023887503 scopus 로고
    • Comparative analysis of the transcripts mapped in the BamHI DNA fragment B of avirulent HSV-1 HFEM, virulent HSV-1 F, and their intratypic recombinant viruses
    • Rösen-Wolff, A., Ben-Hur, T., Becker, Y. and Darai, G. (1988) Comparative analysis of the transcripts mapped in the BamHI DNA fragment B of avirulent HSV-1 HFEM, virulent HSV-1 F, and their intratypic recombinant viruses. Virus Res. 10, 315-324.
    • (1988) Virus Res. , vol.10 , pp. 315-324
    • Rösen-Wolff, A.1    Ben-Hur, T.2    Becker, Y.3    Darai, G.4
  • 28
    • 0024584871 scopus 로고
    • Organotropism of latent herpes simplex virus type 1 is correlated to the presence of a 1.5 kb RNA transcript mapped within the BamHI DNA fragment B (0.738-0.809 map units)
    • Rösen-Wolff, A., Scholz, J. and Darai, G. (1989) Organotropism of latent herpes simplex virus type 1 is correlated to the presence of a 1.5 kb RNA transcript mapped within the BamHI DNA fragment B (0.738-0.809 map units). Virus Res. 12, 43-52.
    • (1989) Virus Res. , vol.12 , pp. 43-52
    • Rösen-Wolff, A.1    Scholz, J.2    Darai, G.3
  • 29
    • 0025673788 scopus 로고
    • Expression of Human immunodeficiency virus type 1 gag gene using genetically engineered herpes simplex virus type 1 recombinants
    • Rösen-Wolff, A., Raab, K., Zöller, L., Darai, G., Eberle, J. and Deinhardt, F. (1990) Expression of Human immunodeficiency virus type 1 gag gene using genetically engineered herpes simplex virus type 1 recombinants. Virus Genes 4, 325-337.
    • (1990) Virus Genes , vol.4 , pp. 325-337
    • Rösen-Wolff, A.1    Raab, K.2    Zöller, L.3    Darai, G.4    Eberle, J.5    Deinhardt, F.6
  • 30
    • 0025971254 scopus 로고
    • Identification and mapping of the UL56 gene transcript of herpes simplex virus type 1
    • Rösen-Wolff, A. and Darai, G. (1991) Identification and mapping of the UL56 gene transcript of herpes simplex virus type 1. Virus Res. 19, 115-126.
    • (1991) Virus Res. , vol.19 , pp. 115-126
    • Rösen-Wolff, A.1    Darai, G.2
  • 31
    • 0025914790 scopus 로고
    • Elimination of UL56 gene by insertion of LacZ cassette between nucleotide position 116030 to 121 753 of herpes simplex virus type 1 abrogates intraperitoneal pathogenicity in tree shrews and mice
    • Rösen-Wolff, A., Lamade, W., Berkowitz, C., Becker, Y. and Darai, G. (1991) Elimination of UL56 gene by insertion of LacZ cassette between nucleotide position 116030 to 121 753 of herpes simplex virus type 1 abrogates intraperitoneal pathogenicity in tree shrews and mice. Virus Res. 20, 205-221.
    • (1991) Virus Res. , vol.20 , pp. 205-221
    • Rösen-Wolff, A.1    Lamade, W.2    Berkowitz, C.3    Becker, Y.4    Darai, G.5
  • 32
    • 0026770038 scopus 로고
    • Determination of the coding capacity of the BamHI DNA fragment B of apathogenic herpes simplex virus type 1 strain HFEM by DNA nucleotide sequence analysis
    • Rösen-Wolff, A., Frank, S., Raab, K., Moyal, M., Becker, Y. and Darai, G. (1992) Determination of the coding capacity of the BamHI DNA fragment B of apathogenic herpes simplex virus type 1 strain HFEM by DNA nucleotide sequence analysis. Virus Res. 25, 189-199.
    • (1992) Virus Res. , vol.25 , pp. 189-199
    • Rösen-Wolff, A.1    Frank, S.2    Raab, K.3    Moyal, M.4    Becker, Y.5    Darai, G.6
  • 34
    • 0023472243 scopus 로고
    • Detection of herpes simplex virus type 1 transcripts during latent infection in mice
    • Spivac, J.G. and Fraser, N.W. (1987) Detection of herpes simplex virus type 1 transcripts during latent infection in mice. J. Virol. 61, 3841-3847.
    • (1987) J. Virol. , vol.61 , pp. 3841-3847
    • Spivac, J.G.1    Fraser, N.W.2
  • 35
    • 0021041568 scopus 로고
    • Physical location of a herpes simplex virus type-1 gene function (s); specifically associated with a 10-million-fold increase in HSV virulence
    • Thompson, R.L., Wagner, E.K. and Stevens J.G. (1983) Physical location of a herpes simplex virus type-1 gene function (s); specifically associated with a 10-million-fold increase in HSV virulence. Virology 131, 180-192.
    • (1983) Virology , vol.131 , pp. 180-192
    • Thompson, R.L.1    Wagner, E.K.2    Stevens, J.G.3
  • 36
    • 0020442864 scopus 로고
    • The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers
    • Viera, J. and Messing, J. (1982) The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers. Gene 19, 259-268.
    • (1982) Gene , vol.19 , pp. 259-268
    • Viera, J.1    Messing, J.2
  • 37
    • 0017290222 scopus 로고
    • Anatomy of herpes simplex virus DNA
    • Wadsworth, S., Hayward, G.S. and Roizman, B. (1976) Anatomy of herpes simplex virus DNA. J. Virol. 17, 503-512.
    • (1976) J. Virol. , vol.17 , pp. 503-512
    • Wadsworth, S.1    Hayward, G.S.2    Roizman, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.