Upregulated expression of cardiac ankyrin-repeated protein in renal podocytes is associated with proteinuria severity in lupus nephritis

Human Pathology

Volumn 38, Issue 3, 2007, Pages 410-419

  Matsuura, Keiko ^a   Uesugi, Noriko ^b   Hijiya, Naoki ^a   Uchida, Tomohisa ^a   Moriyama, Masatsugu ^a  

^a OITA UNIVERSITY   (Japan)

^b FUKUOKA UNIVERSITY   (Japan)

Author keywords

CARP; Lupus nephritis; Nephrotic syndrome; Podocytes

Indexed keywords

ANKYRIN; HEART ANKYRIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DIFFERENTIAL DIAGNOSIS; DISEASE SEVERITY; FEMALE; GLOMERULOPATHY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY BIOPSY; LUPUS ERYTHEMATOSUS NEPHRITIS; MEMBRANOUS GLOMERULONEPHRITIS; MOUSE; MUSCULAR DYSTROPHY; MYOPATHY; NEPHROTIC SYNDROME; NONHUMAN; PODOCYTE; PROTEIN EXPRESSION; PROTEINURIA; RAPIDLY PROGRESSIVE GLOMERULONEPHRITIS; UPREGULATION;

ADULT; AGED; ANIMALS; CHILD; DOXORUBICIN; FEMALE; GLOMERULONEPHRITIS; HUMANS; IMMUNOHISTOCHEMISTRY; KIDNEY; LIPOPOLYSACCHARIDES; LUPUS NEPHRITIS; MALE; MICE; MICE, INBRED BALB C; MIDDLE AGED; MUSCLE PROTEINS; NUCLEAR PROTEINS; PODOCYTES; PROTEINURIA; REPRESSOR PROTEINS; UP-REGULATION; VIMENTIN;

EID: 33846883737     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2006.09.006     Document Type: Article

References (47)

1. Barisoni L., and Mundel P. Podocyte biology and the emerging understanding of podocyte diseases. Am J Nephrol 23 (2003) 353-360
2. Kerjaschki D. Caught flat-footed: podocyte damage and the molecular bases of focal glomerulosclerosis. J Clin Invest 108 (2001) 1583-1587
3. Somlo S., and Mundel P. Getting a foothold in nephrotic syndrome. Nat Genet 24 (2000) 333-335
4. Zou Y., Evans S., Chen J., et al. CARP, a cardiac ankyrin repeat protein, is downstream in the Nkx2-5 homeobox gene pathway. Development 124 (1997) 793-804
5. Chu W., Burns D.K., Swerlick R.A., and Presky D.H. Identification and characterization of a novel cytokine-inducible nuclear protein from human endothelial cells. J Biol Chem 270 (1995) 10236-10245
6. Nakada C., Oka A., Nonaka I., et al. Cardiac ankyrin repeat protein is preferentially induced in atrophic myofibers of congenital myopathy and spinal muscular atrophy. Pathol Int 53 (2003) 653-658
7. Nakada C., Tsukamoto Y., Oka A., et al. Cardiac-restricted ankyrin-repeated protein is differentially induced in Duchenne and congenital muscular dystrophy. Lab Invest 83 (2003) 711-719
8. Ishiguro N., Baba T., Ishida T., et al. Carp, a cardiac ankyrin-repeated protein, and its new homologue, Arpp, are differentially expressed in heart, skeletal muscle, and rhabdomyosarcomas. Am J Pathol 160 (2002) 1767-1778
9. Weening J.J., D'Agati V.D., Schwartz M.M., et al. The classification of glomerulonephritis in systemic lupus erythematosus revisited. Kidney Int 65 (2004) 521-530
10. Weening J.J., D'Agati V.D., Schwartz M.M., et al. The classification of glomerulonephritis in systemic lupus erythematosus revisited. J Am Soc Nephrol 15 (2004) 241-250
11. Yokoyama H., Wada T., Hara A., et al. The outcome and a new ISN/RPS 2003 classification of lupus nephritis in Japanese. Kidney Int 66 (2004) 2382-2388
12. Chen Q., Liu Z., Hu W., Chen H., Zeng C., and Li L. Class V lupus nephritis: a clinicopathologic study in 152 patients. J Nephrol 16 (2003) 126-132
13. Reiser J., von Gersdorff G., Loos M., et al. Induction of B7-1 in podocytes is associated with nephrotic syndrome. J Clin Invest 113 (2004) 1390-1397
14. Teixeira Vde P., Blattner S.M., Li M., et al. Functional consequences of integrin-linked kinase activation in podocyte damage. Kidney Int 67 (2005) 514-523
15. Frasca G.M., Onetti-Muda A., and Renieri A. Thin glomerular basement membrane disease. J Nephrol 13 (2000) 15-19
16. Sorger K. Postinfectious glomerulonephritis. Subtypes, clinico-pathological correlations, and follow-up studies. Veroff Pathol 125 (1986) 1-105
17. Couser W.G. Glomerulonephritis. Lancet 353 (1999) 1509-1515
18. Mundel P., and Shankland S.J. Podocyte biology and response to injury. J Am Soc Nephrol 13 (2002) 3005-3015
19. Tsukamoto Y., Senda T., Nakano T., et al. Arpp, a new homolog of carp, is preferentially expressed in type 1 skeletal muscle fibers and is markedly induced by denervation. Lab Invest 82 (2002) 645-655
20. Shi Y., Reitmaier B., Regenbogen J., et al. CARP, a cardiac ankyrin repeat protein, is up-regulated during wound healing and induces angiogenesis in experimental granulation tissue. Am J Pathol 166 (2005) 303-312
21. Akhtar M., and Al Mana H. Molecular basis of proteinuria. Adv Anat Pathol 11 (2004) 304-309
22. Oh J., Reiser J., and Mundel P. Dynamic (re)organization of the podocyte actin cytoskeleton in the nephrotic syndrome. Pediatr Nephrol 19 (2004) 130-137
23. Eddy A.A., and Symons J.M. Nephrotic syndrome in childhood. Lancet 362 (2003) 629-639
24. Ichimura K., Kurihara H., and Sakai T. Actin filament organization of foot processes in rat podocytes. J Histochem Cytochem 51 (2003) 1589-1600
25. Patek C.E., Fleming S., Miles C.G., et al. Murine Denys-Drash syndrome: evidence of podocyte de-differentiation and systemic mediation of glomerulosclerosis. Hum Mol Genet 12 (2003) 2379-2394
26. Saleem M.A., Ni L., Witherden I., et al. Co-localization of nephrin, podocin, and the actin cytoskeleton: evidence for a role in podocyte foot process formation. Am J Pathol 161 (2002) 1459-1466
27. Srivastava T., Garola R.E., Whiting J.M., and Alon U.S. Synaptopodin expression in idiopathic nephrotic syndrome of childhood. Kidney Int 59 (2001) 118-125
28. Moeller M.J., Soofi A., Hartmann I., et al. Podocytes populate cellular crescents in a murine model of inflammatory glomerulonephritis. J Am Soc Nephrol 15 (2004) 61-67
29. Koop K., Eikmans M., Baelde H.J., et al. Expression of podocyte-associated molecules in acquired human kidney diseases. J Am Soc Nephrol 14 (2003) 2063-2071
30. Benigni A., Gagliardini E., Tomasoni S., et al. Selective impairment of gene expression and assembly of nephrin in human diabetic nephropathy. Kidney Int 65 (2004) 2193-2200
31. Poussu A.M., Virtanen I., Autio-Harmainen H., and Lehto V.P. Podocyte-specific expression of a novel trans-Golgi protein Vear in human kidney. Kidney Int 60 (2001) 626-634
32. Henry J., Miller M.M., and Pontarotti P. Structure and evolution of the extended B7 family. Immunol Today 20 (1999) 285-288
33. Huwiler A., Ren S., Holthofer H., Pavenstadt H., and Pfeilschifter J. Inflammatory cytokines upregulate nephrin expression in human embryonic kidney epithelial cells and podocytes. Biochem Biophys Res Commun 305 (2003) 136-142
34. Han X.J., Chae J.K., Lee M.J., You K.R., Lee B.H., and Kim D.G. Involvement of GADD153 and cardiac ankyrin repeat protein in hypoxia-induced apoptosis of H9c2 cells. J Biol Chem 280 (2005) 23122-23129
35. Aihara Y., Kurabayashi M., Saito Y., et al. Cardiac ankyrin repeat protein is a novel marker of cardiac hypertrophy: role of M-CAT element within the promoter. Hypertension 36 (2000) 48-53
36. Aihara Y., Kurabayashi M., Tanaka T., et al. Doxorubicin represses CARP gene transcription through the generation of oxidative stress in neonatal rat cardiac myocytes: possible role of serine/threonine kinase-dependent pathways. J Mol Cell Cardiol 32 (2000) 1401-1414
37. Kanai H., Tanaka T., Aihara Y., et al. Transforming growth factor-beta/Smads signaling induces transcription of the cell type-restricted ankyrin repeat protein CARP gene through CAGA motif in vascular smooth muscle cells. Circ Res 88 (2001) 30-36
38. Abbate M., Zoja C., Morigi M., et al. Transforming growth factor-beta1 is up-regulated by podocytes in response to excess intraglomerular passage of proteins: a central pathway in progressive glomerulosclerosis. Am J Pathol 161 (2002) 2179-2193
39. Berden J.H. Lupus nephritis. Kidney Int 52 (1997) 538-558
40. Cameron J.S. Lupus nephritis. J Am Soc Nephrol 10 (1999) 413-424
41. Mercadal L., Montcel S.T., Nochy D., et al. Factors affecting outcome and prognosis in membranous lupus nephropathy. Nephrol Dial Transplant 17 (2002) 1771-1778
42. Nossent H.C. Factors associated with active SLE after endstage renal disease. J Rheumatol 26 (1999) 1210-1211
43. Austin H.A., and Illei G.G. Membranous lupus nephritis. Lupus 14 (2005) 65-71
44. Nangaku M., Shankland S.J., and Couser W.G. Cellular response to injury in membranous nephropathy. J Am Soc Nephrol 16 (2005) 1195-1204
45. Ferrario F., and Rastaldi M.P. Histopathological atlas of renal diseases: membranous glomerulonephritis. J Nephrol 17 (2004) 635-636
46. Ponticelli C., and Moroni G. Renal biopsy in lupus nephritis-what for, when and how often?. Nephrol Dial Transplant 13 (1998) 2452-2454
47. Kolasinski S.L., Chung J.B., and Albert D.A. What do we know about lupus membranous nephropathy? An analytic review. Arthritis Rheum 47 (2002) 450-455